depression

Yoga, Depression, & Clinical Trial Critique 101 Posted August 12, 2018 by Hilda Bastian in Evidence, Health http://blogs.plos.org/absolutely-maybe/2018/08/12/yoga-depression-clinical-trial-critique-101/ Not specifically about ME, but I thought it might be of interest to some people who are...

Looks like this is supportive of Wessely's attempts to get change, as written about by @Hole Ousia: https://www.s4me.info/threads/simon-wessely-didnt-want-his-e-mail-on-a-blog-here-it-is-on-hole-ousia.5001/ Also seems relevant to claims that NICE should operate entirely independently of...

Transparency: Revision of NICE guidance on Depression

Andrew Lloyd is a co-author. Open access at https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-018-2763-8

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0200057

from Physician's First Watch June 13, 2018 Use of Common Drugs with Depression as Side Effect Increasing By Kelly Young Edited by - Lorenzo Di Francesco, MD, FACP, FHM Use of common drugs with depression as a possible side effect is increasing -- and the more of these drugs patients take...

I thought this was generally interesting, shedding some light, as it does, on how ketamine and psychedelics affect the brain structurally, and suggesting the possibility of new drugs for depression and anxiety based on these chemicals. Ketamine was also suggested and tried as a treatment for ME...

https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2679767 Medscape article about this study https://www.medscape.com/viewarticle/896396

The article, https://medicalxpress.com/news/2018-05-national-trial-eeg-brain-patients.amp The paper, https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2678040

More at the link: https://medicalxpress.com/news/2018-04-unprecedented-genetic-factors-major-depression.html

Paywalled at http://journals.sagepub.com/doi/abs/10.1177/0269881117746902

Open access at https://www.researchgate.net/publication/322727729_Effects_of_anti-inflammatory_drugs_on_the_expression_of_tryptophan-metabolism_genes_by_human_macrophages

The work was done in mice. The method used to modulate dopamine levels - optogenetics - was new to me, and fascinating. The researchers think their work has relevance to depression and PTSD. Should low dopamine levels prove to be relevant in ME, some of the results from the study may also...

Note: the UK Biobank is not the same as the UK ME/CFS Biobank. Open access at https://www.nature.com/articles/s41467-018-03819-3

Sorry for the long post. Translation by Google and me. Mistakes and bold/italics by me. http://www.zeit.de/news/2018-03/27/drei-todesfaelle-bornavirus-fuer-menschen-doch-gefaehrlich-180327-99-652639 Berlin/Greifswald-Riems (dpa) Three patients in Germany have died as a result of a viral...

http://www.dailymail.co.uk/health/article-5438153/Years-depression-linked-brain-inflammation.html Not a new observation by any means but this is the first time I've seen measures of neuroinflammation quantified and correlated with duration.

Rest of the short article can be read at http://neurosciencenews.com/depression-prevalence-research-8314/

Paywalled at https://www.nature.com/articles/s41593-017-0010-3 New Scientist article on this, https://www.newscientist.com/article/2153139-how-social-stress-makes-your-brain-vulnerable-to-depression/

http://neurosciencenews.com/microbiome-depression-8228/

A few people were interested in delving into the thorny issue of depression. Here's a nice place to start. Eiko Fried summarises why depression is not a useful concept for research - in a series of 18 tweets. Click on the first tweet here and the other 17 will appear underneath: I will post...