pain

An amygdalar neural ensemble that encodes the unpleasantness of pain.

https://www.bbc.co.uk/news/health-50151723 People with long-term health problems such as arthritis are more likely to feel pain on humid days, a study has suggested. Folklore suggests the cold makes pain worse - but there is actually little research into the weather's effects. And this...

International Association for the Study of Pain seems to be an intended explicit move to bPS model of pain. https://www.iasp-pain.org/PublicationsNews/NewsDetail.aspx?ItemNumber=9218&navItemNumber=643 eta: the survey for submission of comments is here...

https://newatlas.com/blood-test-chronic-pain/54507/

Haven't got the energy to track down the study/studies this is based on but sounds potentially interesting (and definitely so if you're a mouse - do we not have a mouse emoji? We can't be discussing science and not honour mice with an emoji!)...

Will an app a day, keep the doctor away? A critical look at BPS based phone apps. In my opinion, these apps may not be designed to keep the doctor away, but to keep patients away from their doctors - in a "don't bother us with your imaginary health problems," kind of way. They seem to be...

Saw this on Twitter Designed for menstrual cramp - brilliant for pain relief for so many conditions Hope it is mass manufactured soon https://news.engineering.utoronto.ca/this-ultra-thin-hot-water-bottle-could-help-ease-menstrual-pain/

https://www.ncbi.nlm.nih.gov/pubmed/31282597 https://onlinelibrary.wiley.com/doi/abs/10.1111/papr.12817?af=R&

I have seen some discussions here and there around the puzzling fact of muscle pain being a consequence of neural exhaustion, whatever that actually means in pathophysiology, but not within a formal thread. It's not quite clear how much distinction there is between PEM and PENE. Maybe they are...

https://www.efna.net/new-brain-mind-and-pain-book-of-evidence-released-for-the-2019-2024-eu-mandate/ Direct link to document (PDF), http://www.brainmindpain.eu/wp-content/uploads/2019/04/BMP-Book-of-Evidence-%E2%80%93-2019-2024-web.pdf

hi I have a very low dose of Lyrica aka Pregabalin for neuropathic pain which I get in hands and feet most noticeably at night. I had a bad experience with it when I first started taking it because I’m one of those who are knocked out by medications. I’ve stopped taking amitryptiline or...

Hyperactivation of proprioceptors induces microglia-mediated long-lasting pain in a rat model of chronic fatigue syndrome https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-019-1456-x Personally I do not like this 'rat model' of CFS, I don't think there is anyway that they...

(List reported taken from the Mirror) full list here: note (ME not on list but FM is) https://www.cambridge-news.co.uk/news/uk-world-news/cambridge-migraine-endometriosis-arthritis-nhs-15339123

https://www.nytimes.com/2019/03/16/opinion/sunday/pain-opioids.html I saw this in the opinions today. It's a short read and I must say it is fluff. Summary: -The author notes that opioids have proven to be ineffective and even counterproductive for treating chronic pain (okay). -From that...

Pain is one of the symptoms frequently reported by patients. What are your experiences with CBD (Cannabidiol)? An article has appeared on the BBC website about the growing use of CBD in the UK. https://www.bbc.co.uk/programmes/articles/1v5vxpY7zkVkJLLSsvRXvqJ/why-is-cbd-on-everyones-lips

rest of details here: https://www.kcl.ac.uk/ioppn/news/records/2019/march/pioneering-pain-research-leads-to-landmark-deal (No CBT!)

Open access at https://www.degruyter.com/view/j/sjpain.2019.19.issue-1/sjpain-2018-2007/sjpain-2018-2007.xml

Thought this might be of interest. https://academic.oup.com/rheumatology/advance-article-abstract/doi/10.1093/rheumatology/kez027/5366191 Sci Hub, https://sci-hub.tw/https://academic.oup.com/rheumatology/advance-article-abstract/doi/10.1093/rheumatology/kez027/5366191

An objective biomarker - gene expression patterns - for pain? Can this be true? https://www.nature.com/articles/s41380-018-0345-5 (A.B Niculescu et al.) Full text. The cohorts and the scientists are psychiatric patients/psychiatrists but otherwise the study seems to lean more biomedical - not...

https://www.psychologytoday.com/us/blog/mindfulness-in-frantic-world/201902/mindfulness-could-be-powerful-painkiller Article doesn't mention CFS so far as I can see - just pain, mainly women. Given IAPT in UK (and MUS etc stuff) I thought this might be of interest.