I have seen some discussions here and there around the puzzling fact of muscle pain being a consequence of neural exhaustion, whatever that actually means in pathophysiology, but not within a formal thread.
It's not quite clear how much distinction there is between PEM and PENE. Maybe they are...
https://www.efna.net/new-brain-mind-and-pain-book-of-evidence-released-for-the-2019-2024-eu-mandate/
Direct link to document (PDF), http://www.brainmindpain.eu/wp-content/uploads/2019/04/BMP-Book-of-Evidence-%E2%80%93-2019-2024-web.pdf
hi I have a very low dose of Lyrica aka Pregabalin for neuropathic pain which I get in hands and feet most noticeably at night. I had a bad experience with it when I first started taking it because I’m one of those who are knocked out by medications. I’ve stopped taking amitryptiline or...
Hyperactivation of proprioceptors induces microglia-mediated long-lasting pain in a rat model of chronic fatigue syndrome
https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-019-1456-x
Personally I do not like this 'rat model' of CFS, I don't think there is anyway that they...
(List reported taken from the Mirror)
full list here:
note (ME not on list but FM is)
https://www.cambridge-news.co.uk/news/uk-world-news/cambridge-migraine-endometriosis-arthritis-nhs-15339123
https://www.nytimes.com/2019/03/16/opinion/sunday/pain-opioids.html
I saw this in the opinions today. It's a short read and I must say it is fluff.
Summary:
-The author notes that opioids have proven to be ineffective and even counterproductive for treating chronic pain (okay).
-From that...
Pain is one of the symptoms frequently reported by patients.
What are your experiences with CBD (Cannabidiol)?
An article has appeared on the BBC website about the growing use of CBD in the UK.
https://www.bbc.co.uk/programmes/articles/1v5vxpY7zkVkJLLSsvRXvqJ/why-is-cbd-on-everyones-lips
Thought this might be of interest.
https://academic.oup.com/rheumatology/advance-article-abstract/doi/10.1093/rheumatology/kez027/5366191
Sci Hub, https://sci-hub.tw/https://academic.oup.com/rheumatology/advance-article-abstract/doi/10.1093/rheumatology/kez027/5366191
An objective biomarker - gene expression patterns - for pain? Can this be true?
https://www.nature.com/articles/s41380-018-0345-5 (A.B Niculescu et al.) Full text.
The cohorts and the scientists are psychiatric patients/psychiatrists but otherwise the study seems to lean more biomedical - not...
https://www.psychologytoday.com/us/blog/mindfulness-in-frantic-world/201902/mindfulness-could-be-powerful-painkiller
Article doesn't mention CFS so far as I can see - just pain, mainly women.
Given IAPT in UK (and MUS etc stuff) I thought this might be of interest.
Gender Bias in Pediatric Pain Assessment
https://academic.oup.com/jpepsy/advance-article-abstract/doi/10.1093/jpepsy/jsy104/5273626?redirectedFrom=fulltext
Journal of Pediatric Psychology, jsy104, https://doi.org/10.1093/jpepsy/jsy104
Brian D Earp et al, Published: 04 January 2019 (Paywall)...
From the press release:
https://mcgill.ca/newsroom/channels/news/men-and-women-remember-pain-differently-293050
Based on this article: Male-Specific Conditioned Pain Hypersensitivity in Mice and Humans
Loren J. Martin et al, Published: January 10, 2019...
Relationship Between Exercise-induced Oxidative Stress Changes and Parasympathetic Activity in Chronic Fatigue Syndrome: An Observational Study and in Patients and Healthy Subjects
Email the author MSc Andrea Polli,Jessica Van Oosterwijck, PhD,Jo Nijs, PhD,
Uros Marusic, PhD,Inge De Wandele...
I'm still skeptical. It sounds like he is encouraging patients to hide their symptoms and behave more normally, and even a temporary change in that direction is taken as evidence that a mysterious mind-body illness was successfully treated.
This is also not innovative. It's the same old...
Marieke Jepma, Leonie Koban, Johnny van Doorn, Matt Jones, Tor D. Wager.
Behavioural and neural evidence for self-reinforcing expectancy effects on pain.
Nature Human Behaviour, 2018; 2 (11): 838
DOI: 10.1038/s41562-018-0455-8
Link: https://www.nature.com/articles/s41562-018-0455-8
Abstract...
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