mitochondria

  1. Inara

    Viruses Attack Mitochondria to Travel and Spread Within the Nervous System

    Didn't find it elsewhere: I've just realized the publication and article are from 2012: https://www.cell.com/cell-host-microbe/fulltext/S1931-3128%2812%2900104-7 (Kramer, Engquist). Maybe still interesting for "ME newbies" (like myself)? And what did become of it?
  2. Andy

    Nature: Newly made mitochondrial DNA drives inflammation

    https://www.nature.com/articles/d41586-018-05764-z
  3. A

    Mitochondrial research

    Thought this was interesting http://www.sciencemag.org/news/2016/02/why-do-our-cells-power-plants-have-their-own-dna
  4. Andy

    Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism, 2018, Tan et al

    Open access at https://www.frontiersin.org/articles/10.3389/fimmu.2018.01605/full
  5. Andy

    Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity, 2018, Zhang et al

    No idea if it's of interest to us but it sounds impressive. Paywalled at http://stke.sciencemag.org/content/11/538/eaaq0702.full
  6. Indigophoton

    Dying Organs Restored to Life in Novel Experiments

    Very interesting use of mitochondria - as transplants to replace damaged versions in human organs. https://mobile.nytimes.com/2018/07/10/health/mitochondria-transplant-heart-attack.html
  7. Indigophoton

    Reduced glycolytic reserve in isolated natural killer cells from ME/CFS patients: A preliminary investigation, Nguyen et al, 2018

    https://www.ncbi.nlm.nih.gov/pubmed/29981562 The DOI (digital object identifier, aka ID number) for this doesn't seem to work, so I'm not sure anything beyond the abstract has been published yet.
    • Indigophoton
    • Thread
    • 2018 glycolysis immunology marshall-gradisnik me/cfs mitochondria natural killer cells ncned nguyen paper staines
    • Replies: 22
    • Forum: ME/CFS research
  8. Andy

    Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress, 2018, Lee et al

    Paywalled at https://www.cell.com/cell-metabolism/abstract/S1550-4131(18)30390-5 Article on the study https://news.usc.edu/145046/mitochondrial-dna-nuclear-dna-work-together-usc-study/
  9. Sly Saint

    Disease-causing stomach bug attacks energy generation in host cells

    " Researchers report in a new study that the bacterium Helicobacter pylori - a major contributor to gastritis, ulcers and stomach cancer—resists the body's immune defenses by shutting down energy production within the cells of the stomach lining that serve as a barrier to infection. " The human...
  10. Indigophoton

    Impaired energy production may explain why brain is susceptible to age-related diseases

    This may be of interest to some, The article, https://medicalxpress.com/news/2018-05-impaired-energy-production-brain-susceptible.amp The paper, https://www.cell.com/cell-reports/fulltext/S2211-1247(18)30703-4
  11. Indigophoton

    Rehabilitating lactate: From poison to cure

    The article, https://phys.org/news/2018-05-lactate-poison.amp The paper, https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30186-4? Full paper here, http://sci-hub.tw/10.1016/j.cmet.2018.03.008
  12. Indigophoton

    GABA, GABA, GABA, what does it actually do in the brain?

    This might be of background interest to some. https://medicalxpress.com/news/2018-05-gaba-brain.amp
  13. Indigophoton

    Review Article: Mitochondria: An Organelle of Bacterial Origin Controlling Inflammation, Meyer et al, 2018

    May be of general background interest for some, https://www.frontiersin.org/articles/10.3389/fimmu.2018.00536/full
  14. Indigophoton

    Solving the structure of ATP synthase

    Posting this because of its relevance to energy production and metabolic disease. https://phys.org/news/2018-04-atp-synthase.html The paper, http://science.sciencemag.org/content/early/2018/04/11/science.aas9699 Edit: fixed link
  15. Indigophoton

    Scientists discover a pathway that monitors a protein import into mitochondria

    https://phys.org/news/2018-04-scientists-pathway-protein-import-mitochondria.amp The paper, http://science.sciencemag.org/content/360/6385/eaan4146
  16. Melanie

    Defeating Diseases with Energy (2018) Scientific American

    Although Mitochondria may very well be related to ME/CFS the article does not mention it so I chose to put it under the heading "Health News and Research unrelated to ME/CFS". Defeating Diseases with Energy
  17. Indigophoton

    Article: Scientists discover that cells contain mitochondria specialized to build fats

    The discovery of a subset of mitochondria that have a different type of function. https://phys.org/news/2018-04-scientists-cells-mitochondria-specialized-fats.amp The full paper is here,
  18. Andy

    Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells, 2015, Chinopoulos et al

    I think this might be of interest to us but really it's so technical I'm out of my depth. What caught my attention was recalling that this recent study claimed that itaconate is an anti-inflammatory metabolite (recent forum thread on the study here) and reading the Wikipedia article that...
  19. Webdog

    Mitochondrial Disease Patients Face Difficult Road to Diagnosis

    The most common misdiagnosis is... you guessed it... psychiatric disorder. https://www.mailman.columbia.edu/public-health-now/news/mitochondrial-disease-patients-face-difficult-road-diagnosis
  20. Andy

    Labroots: Cell Stress Elongates Mitochondria

    Thought this was interesting, no idea if it's useful or not though. https://www.labroots.com/trending/cell-and-molecular-biology/8312/cell-stress-elongates-mitochondria
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