Age-related fatigue is associated with reduced mitochondrial function in peripheral blood mononuclear cells : Herpich et al 2020

https://www.sciencedirect.com/science/article/abs/pii/S0531556520305258?dgcid=rss_sd_all

 

Is it, though?

Is it?

Interesting but this definition is weird.

 

Indeed – the study was done by a German team, though, so in fairness it could just be an odd translation of something that was already a bit truncated by the abstract form.

 

I don't think the authors know what it is they want to study. They talk of age-related fatigue but that is not the same as fatigue, in comparison to no fatigue, in the elderly. Fatigue in comparison to no fatigue in yougsters might be the same. Moreover, unless they have looked carefully to see why the fatigued people are fatigued the whole thing seems pointless. Even more pointless when PBMCs are likely to give no indication of any metabolic problem that might cause fatigue.

I think this is mitochondriobabble.

 

Ouroboros reminds me of series 7 of Red Dwarf with Lister going back in time to become his own parent.

As for fatigue, before I got ME I had disabling fatigue for 6 years but it was relieved by sleep - I just couldn't get enough sleep due to living in a noisy environment and having to attend college/work. I needed 10 hours of sleep.