fatigue

Chronic fatigue syndrome in MS: an endogenous response pattern to an immunological challenge mediated by orexin/hypocretin? Hildebrandt, Helmut; Stuke, Heiner Abstract Fatigue is a common and disabling symptom in patients with inflammatory or autoimmune diseases like Multiple Sclerosis...

Transdiagnostic cognitive behavioral therapy for severe and persistent fatigue – a feasibility study in primary care Frank Svärdman, Conrad Samuelsson, Ludwig Franke Föyen, Anna Oremark, Anna Högfeldt, Jacob Andersson Emad, Douglas Sjöwall, Christian Rück, Erik Hedman-Lagerlöf, Hans Knoop, Elin...

Abstract: Fatigue is a common symptom of cancer patients, which can impair quality of life even years after treatment. Little is known about genetic determinants of fatigue, especially in prostate cancer (PCa). This study aims to identify SNPs associated with long-term fatigue in a prospective...

The cyclic alternating pattern demonstrates increased sleep instability and correlates with fatigue and sleepiness in adults with upper airway resistance syndrome Christian Guilleminault, M Cecilia Lopes, Chad C Hagen, Agostinho da Rosa...

Chronic insomnia remitting after maxillomandibular advancement for mild obstructive sleep apnea: a case series Michael Proothi, Victor J R Grazina, Avram R Gold https://pmc.ncbi.nlm.nih.gov/articles/PMC6693215/ (PDF available) Background: Chronic insomnia and obstructive sleep apnea are both...

Obstructive sleep apnea is a common disorder in the population—a review on the epidemiology of sleep apnea Karl A Franklin, Eva Lindberg https://pmc.ncbi.nlm.nih.gov/articles/PMC4561280/ (PDF available) Abstract The prevalence of obstructive sleep apnea (OSA) defined at an apnea-hypopnea index...

Objective versus subjective excessive daytime sleepiness in OSA: Quantifying the impact of fatigue Morris S Gold, Riccardo A Stoohs, Avram R Gold https://www.sciencedirect.com/science/article/abs/pii/S1389945726001061 Background In patients with obstructive sleep apnea (OSA), excessive daytime...

Background Fatigue persists as a dominant and debilitating phenomenon in long-COVID, yet its underlying biological mechanisms remain unclear. While inflammatory variables tend to normalize within months post-infection, fatigue continues to significantly impact quality of life. Understanding...

Key Points Question Is transcutaneous electrical nerve stimulation (TENS) effective for treating pain when combined with physical therapy (PT) in individuals with fibromyalgia? Findings This cluster randomized clinical trial of 459 participants with fibromyalgia from 28 PT clinics from 6...

Not quite sure where to put this. MEA promoting a study focussed on just fatigue in ME/CFS and Long Covid lumped together is a little concerning. never mind the requirement to travel to Oxford to do it which will select the mildest patients for a lengthy appointment to measure brain waves...

Abstract Background The physical and psychological impact of caring for patients during a coronavirus public health emergency had adverse effects on healthcare workers (HCW), including fatigue. Aims To examine the prevalence of fatigue among HCW during severe acute respiratory syndrome (SARS)...

Acute inflammation and fronto-striatal connectivity in the transition from acute to persistent fatigue after mild COVID-19: A longitudinal fMRI study Background Persistent fatigue is one of the most common and disabling sequelae of COVID-19, yet its neurobiological mechanisms remain poorly...

Evidence of Accumulating Neurophysiologic Dysfunction in Persistent Post-COVID Fatigue [Line breaks added] Abstract A major consequence of the COVID-19 pandemic has been the emergence of post-COVID syndrome (PCS), and more specifically, post-COVID fatigue (pCF), with an estimated prevalence...

I had a mini brainwave and thought why not just go with 'chronic malaise syndrome' as a temporary name as no-one really uses malaise do they, not 'chronic malaise' in the same way as 'chronic fatigue' (?)..........Wrong. full details https://icdlist.com/icd-10/codes/malaise-and-fatigue-r53

Somatic arousal and sleepiness/fatigue among patients with sleep-disordered breathing Morris S. Gold, Tshering Amdo, Nadia Hasaneen and Avram R. Gold https://www.researchgate.net/publication/289535169_Somatic_arousal_and_sleepinessfatigue_among_patients_with_sleep-disordered_breathing Sci-Hub...

Feasibility of predicting next-day fatigue levels using heart rate variability and activity-sleep metrics in people with post-COVID fatigue [Line breaks added] Background Post-COVID fatigue (pCF) represents a significant burden for many individuals following SARS-CoV-2 infection. The...

Peripheral Levels of Selected Biomarkers in Patients with Post-Sarcoidosis Chronic Fatigue Syndrome [Line breaks added] Introduction Chronic fatigue syndrome (CFS) is characterized by persistent fatigue and multiple symptoms such as cognitive impairment and muscle pain, often linked to...

Post-COVID Fatigue Is Associated With Reduced Cortical Thickness After Hospitalization OBJECTIVE Neuropsychiatric symptoms are among the most prevalent sequelae of COVID-19, particularly among hospitalized patients. Recent research has identified volumetric brain changes associated with...

Recently, a few discussions over terms have caught my attention on two terms that I think can make discussions of ME/CFS make more sense. Obviously terminology is a fraught issue, we are still tainted by the 'chronic fatigue' label after all this time, and this is mainly because to retire...

Book: The scientific basis of fatigue, 2025, Martin et al. [Need to edit cause need to figure out how to add tags] About the book Key Features Reviews molecular and cellular aspects of chronic fatigue syndrome Outlines fatigue in relation to various conditions including diabetes, Parkinson’s...