Why are women more fatigued than men? The roles of stress, sleep, and repetitive negative thinking
Shima Golmohamadi, Bronwyn M. Graham
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Abstract
Fatigue, a state of prolonged tiredness that cannot be alleviated through rest, is twice as likely to affect women than men. To...
Post-COVID-19 syndrome and low-grade inflammation: exploring gender and occupational inequalities in a retrospective cohort study
Yanhui, Lin; Jiangang, Wang; Jianping, Gao; Tao, Wang
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Background
To investigate the association between post-coronavirus disease 2019...
c-reactive protein
chronic inflammation
cough
dizziness
fatigue
healthcare workers
hscrp
long covid
neutrophil:lymphocyte ratio
nlr
palpitations
platelet:lymphocyte ratio
plr
Efficacy of pharmacologic treatments for fatigue in multiple sclerosis: A systematic review and meta-analysis
Karlo Toljana, Albert Aboseifb, Moein Amina
Highlights
• Amantadine and modafinil are the most studied medications for fatigue in MS.
• In a pooled analysis, medications demonstrated...
Characterization, Treatment, and Long-term Follow-up of Fatigued Patients in Primary Care (iFAS)
Elin Lindsäter et al, Karolinska Institutet, Stockholm, Sweden
https://clinicaltrials.gov/study/NCT06786832
Study Start (Estimated): 2025-01
Primary Completion (Estimated): 2027-06
Enrollment...
Individual Intensive Short Term Psychodynamic Psychotherapy for Patients with Treatment Resistance Persistent Physical Symptoms
ISTDP for Patients with Treatment Resistance PPS
https://clinicaltrials.gov/study/NCT06682104
Daniel Maroti, Stockholm University, Sweden
"Study Overview
Brief...
Abstract:
Approximately 10% of patients experience persistent symptoms following COVID-19, known as long-COVID syndrome. This cross-sectional study explored factors of quality of life (QoL) in 53 long-COVID patients.
QoL was measured using the World Health Organization-Five Well-Being Index...
Post-coronavirus disease 2019–associated symptoms among children and adolescents in the SARS-CoV-2 Omicron era
Anne Schlegtendal, Christoph Maier, Julien Stein, Jakob Höpner, Astrid Petersmann, Denisa Drinka, Reinhard Berner, Thomas Lücke, Nicole Toepfner, Folke Brinkmann
Purpose
Lack of a...
Abstract:
Introduction
Post COVID-19 neurological sequelae (popularly termed “Long COVID”), which include chronic sleep disruption and “brain fog” are widespread; however, studies have not yet comprehensively evaluated the concurrent effects of these disruptions of neurocognitive function and...
Association Between Chronic Pain and Fatigue Severity with Weather and Air Pollution Among Females with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Chloe Lisette Jones, Olivia Haskin, Jarred Wayne Younger
Abstract
Weather and air quality conditions have been anecdotally...
Full title:
Comparative effectiveness of cognitive behavioural therapy, modafinil, and their combination for treating fatigue in multiple sclerosis (COMBO-MS): a randomised, statistician-blinded, parallel-arm trial
Background
Fatigue is one of the most disabling symptoms reported by people...
Effects of a plank-based strength training programme on muscle activation in patients with long COVID: a case series
https://pubmed.ncbi.nlm.nih.gov/39364804/
Abstract
Background: This study aimed to analyse the effects of a plank-based strength training programme on muscle activation in...
Improved Fatigue Management in Primary Sjögren's Syndrome: A Retrospective Analysis of the Efficacy of Methotrexate in Chinese Patients
Meiju Zhou, Xiaona Dai, Fang Yuan
Abstract
Objective: To assess the efficacy of methotrexate (MTX) and hydroxychloroquine (HCQ) in improving fatigue...
Full title: Use of passively collected actigraphy data to detect individual depressive symptoms in a clinical subpopulation and a general population.
The presentation of major depressive disorder (MDD) can vary widely due to its heterogeneity, including inter- and intraindividual symptom...
Abstract
The main objective was to evaluate structural and functional connectivity correlates of fatigue in post-COVID syndrome, and to investigate the relationships with an objective measure of mental fatigue and with subjective cognitive complaints. One-hundred and twenty-nine patients were...
Highlights
• Persistent symptoms were greater following the first SARS-CoV-2 infection.
• The most frequent persistent symptoms were fatigue, tiredness and shortness of breath.
• Proportion of persistent symptoms varied by variant of infection.
• A reduction of persistent symptoms after COVID-19...
Now published - link here
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The remote diet intervention to reduce Long COVID symptoms trial (ReDIRECT): protocol for a randomised controlled trial to determine the effectiveness and cost-effectiveness of a remotely delivered supported weight management programme for people...
Discussion moved from this thread
But the question is - what is 'exhaustion' in the context of ME/CFS. We have little evidence that it is actually depletion of energy reserves or a 'run down battery'. It certainly seems to feel like that but there is no shortage of oxygen or glucose and almost...
Numerous people are being diagnosed as having CFS and fibro after apparent remission of sarcoidosis. Numerous questions arise
1) What does the diagnoser know about CFS or fibro?
2) What does the diagnoser know about work on post sarcoid fatigue vs sarcoid e.g. persistent shift to TH1 in post...
Faecal microbiota transplantation for sleep disturbance in post-acute COVID-19 syndrome
Raphaela I. Lau, Qi Su, Jessica Y.L. Ching, Rashid N. Lui, Ting Ting Chan, Marc T.L. Wong, Louis H.S. Lau, Yun Kwok Wing, Rachel N.Y. Chan, Hanson Y.H. Kwok, Agnes H.Y. Ho, Yee Kit Tse, Chun Pan Cheung, Moses...
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