mitochondria

  1. Andy

    Gut bacteria signaling to mitochondria in intestinal inflammation and cancer, 2019, Jackson and Theiss

    Open access at https://www.tandfonline.com/doi/full/10.1080/19490976.2019.1592421
    • Andy
    • Thread
    • colitis-associated cancer colon cancer inflammatory bowel disease metabolism microbiome mitochondria
    • Replies: 0
    • Forum: Other health news and research
  2. J

    Mitochondrial complex activity in permeabilised cells of chronic fatigue syndrome patients (2019) Tomas, Brown, Newton, Elson

    https://peerj.com/articles/6500.pdf
    • John Mac
    • Thread
    • 2019 audrey brown cara tomas elson julia newton me/cfs mitochondria paper
    • Replies: 37
    • Forum: ME/CFS research
  3. Andy

    Article: The role of mitochondria in ME/CFS: a perspective, 2019, Tomas and Elson

    Paywalled at https://www.tandfonline.com/doi/full/10.1080/21641846.2019.1580855 Sci Hub, http://sci-hub.tw/https://www.tandfonline.com/doi/full/10.1080/21641846.2019.1580855
    • Andy
    • Thread
    • 2019 bioenergetics elson me/cfs mitochondria mitochondrial dna tomas
    • Replies: 12
    • Forum: ME/CFS research news
  4. R

    Changes in the transcriptome of circulating immune cells of a NZ cohort with ME/CFS (2019) Sweetman et al

    I saw this posted on the "ME/CFS-Evolving Science" facebook page... Changes in the transcriptome of circulating immune cells of a New Zealand cohort with myalgic encephalomyelitis/chronic fatigue syndrome Eiren Sweetman, Margaret Ryan, Christina Edgar, Angus MacKay, Rosamund Vallings, Warren...
    • RoseE
    • Thread
    • 2019 circadian inflammation me/cfs metabolic dysregulation mitochondria mitochondrial dysfunction new zealand oxidative stress paper sweetman transcriptome
    • Replies: 21
    • Forum: ME/CFS research
  5. Andy

    Mitochondrial complex III is essential for suppressive function of regulatory T cells, 2019, Chandel et al

    Open access (PDF file) at https://www.nature.com/articles/s41586-018-0846-z.epdf?shared_access_token=WAkCBVS3L3DO0bM6CbjKJ9RgN0jAjWel9jnR3ZoTv0NUSr5JeVHn5ILb4ngHL_BsTJMx2GJRjntjSBzshFZ8yE4tC3l6CzSLy6_zVux-gc6CNyCRZyfQaZAXy__EeJqkVjgWHo5q5hftEAvdjdhYIjKN3PqYRuicN1bmJ64vvgs%3D
  6. Andy

    Mitochondria Play an Unexpected Role in Killing Bacteria

    https://www.the-scientist.com/the-literature/mitochondria-play-an-unexpected-role-in-killing-bacteria-65246
    • Andy
    • Thread
    • immunology macrophages mitochondria mitochondrial function pathogens reactive oxygen species white blood cells
    • Replies: 6
    • Forum: Other health news and research
  7. Andy

    Chronic fatigue syndrome and mitochondrial dysfunction, 2009, Myhill et al

    An old study but, as shown in this thread, https://s4me.info/threads/top-10-sc...f-citations-tweet-by-dr-mark-gutheridge.7461/, one of the most cited ME/CFS papers in the past 10 years, so thought it might be useful to have here. Open access at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680051/
    • Andy
    • Thread
    • 2009 metabolism mitochondria myhill neutrophils oxidative phosphorylation
    • Replies: 1
    • Forum: ME/CFS research
  8. Andy

    A predictive algorithm to identify genes that discriminate individuals with fibromyalgia syndrome diagnosis from healthy controls, 2018, Saliqan et al

    Open access at https://www.dovepress.com/a-predictive-algorithm-to-identify-genes-that-discriminate-individuals-peer-reviewed-fulltext-article-JPR
  9. Andy

    SMCI RAMSAY 2018: “Biomarkers of mitochondrial dysfunction and signaling in ME/CFS”, Blomberg and Rosen

    2018 Ramsay Award recipients https://solvecfs.org/ramsay-2018-meet-professor-jonas-blomberg-md-phd-dr-anders-rosen-md-phd/
    • Andy
    • Thread
    • 2018 biomarker blomberg immunology me/cfs mitochondria paper rosen solve mecfs initiative
    • Replies: 2
    • Forum: ME/CFS research
  10. Andy

    Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2, 2018, Goffart et al

    Open access at https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gky793/5088042
  11. Andy

    Parkin and PINK1 mitigate STING-induced inflammation, 2018, Youle et al

    Paywalled at https://www.nature.com/articles/s41586-018-0448-9 Article from Nature about this study https://www.nature.com/articles/d41586-018-05988-z
  12. Indigophoton

    Metabolic features and regulation of the healing cycle—A new model for chronic disease pathogenesis and treatment, Robert K Naviaux, 2018

    Not specifically about ME, but includes CFS in the list of conditions considered. https://www.sciencedirect.com/science/article/pii/S1567724918301053#tf0005
    • Indigophoton
    • Thread
    • 2018 allostatic load antipurinergic therapy cell danger response chronic illness healing cycle integrated stress response m0 m1 m2 mitochondria metabokines metabolic memory mitochondria mitochondrial nexus naviaux purinergic signaling
    • Replies: 71
    • Forum: Other health news and research
  13. Inara

    Viruses Attack Mitochondria to Travel and Spread Within the Nervous System

    Didn't find it elsewhere: I've just realized the publication and article are from 2012: https://www.cell.com/cell-host-microbe/fulltext/S1931-3128%2812%2900104-7 (Kramer, Engquist). Maybe still interesting for "ME newbies" (like myself)? And what did become of it?
  14. Andy

    Nature: Newly made mitochondrial DNA drives inflammation

    https://www.nature.com/articles/d41586-018-05764-z
  15. A

    Mitochondrial research

    Thought this was interesting http://www.sciencemag.org/news/2016/02/why-do-our-cells-power-plants-have-their-own-dna
  16. Andy

    Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism, 2018, Tan et al

    Open access at https://www.frontiersin.org/articles/10.3389/fimmu.2018.01605/full
  17. Andy

    Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity, 2018, Zhang et al

    No idea if it's of interest to us but it sounds impressive. Paywalled at http://stke.sciencemag.org/content/11/538/eaaq0702.full
  18. Indigophoton

    Dying Organs Restored to Life in Novel Experiments

    Very interesting use of mitochondria - as transplants to replace damaged versions in human organs. https://mobile.nytimes.com/2018/07/10/health/mitochondria-transplant-heart-attack.html
  19. Indigophoton

    Reduced glycolytic reserve in isolated natural killer cells from ME/CFS patients: A preliminary investigation, Nguyen et al, 2018

    https://www.ncbi.nlm.nih.gov/pubmed/29981562 The DOI (digital object identifier, aka ID number) for this doesn't seem to work, so I'm not sure anything beyond the abstract has been published yet.
    • Indigophoton
    • Thread
    • 2018 glycolysis immunology marshall-gradisnik me/cfs mitochondria natural killer cells ncned nguyen paper staines
    • Replies: 22
    • Forum: ME/CFS research
  20. Andy

    Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress, 2018, Lee et al

    Paywalled at https://www.cell.com/cell-metabolism/abstract/S1550-4131(18)30390-5 Article on the study https://news.usc.edu/145046/mitochondrial-dna-nuclear-dna-work-together-usc-study/
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