Background: Some patients with acute COVID-19 are left with persistent, debilitating fatigue, cognitive impairment (“brain fog”), orthostatic intolerance (OI) and other symptoms (“Long COVID”). Many of the symptoms are like those of other post-infectious fatigue syndromes and may meet criteria...
Abstract
Background: Myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) is a disabling multi-system complex disorder with prevalence of 875 per 100,000 (up to 3.4 million people) in the United States. There are no known etiologic or risk factors and no approved treatments for ME/CFS...
Objectives
A comparison of the nutritional biomarkers between ME/CFS subjects and healthy controls (HC) was undertaken on secondary data collected from an IRB approved cross-sectional study in ME/CFS patients.
Methods
ME/CFS participants were recruited per the 2018 revised Canadian Clinical...
I've recently come across the problem of a name for ME/CFS in the Maori language seemingly being created by a translator to be the equivalent of 'chronic fatigue' but using an uncommon word for 'chronic' that can also mean loitering and shirking. (discussed here News from Aotearoa/New Zealand...
Abstract
We have previously demonstrated that platelet poor plasma (PPP) obtained from patients with LongCovid/Post-Acute Sequelae of COVID-19 (PASC) is characterized by a hypercoagulable state reflected in hyperactivated platelets and the presence of considerable numbers of fibrin(ogen) amyloid...
Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious, complex, and highly debilitating long-term illness. People with ME/CFS are typically unable to carry out their routine activities. Key hallmarks of the disease are neurological and gastrointestinal impairments...
Small adrenal glands in chronic fatigue syndrome: a preliminary computer tomography study
Scott LV, Teh J, Reznek R, Martin A, Sohaib A, Dinan TG.
https://pubmed.ncbi.nlm.nih.gov/10451910/
Abstract
No inclusive or satisfactory biomedical explanation for chronic fatigue syndrome (CFS) has as...
Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a multisystem disease, the pathogenesis of which remains undetermined. We set out to determine the precise abnormalities of gene expression in the blood of patients with CFS/ME. We analyzed gene expression in peripheral blood from 25...
Many people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome are too ill to work.
But there are some in some professions who may be able to with the right supports.
This 2008 US document gives some useful ideas https://www.dropbox.com/s/hbzmju5g8t3ae9o/CFS.pdf?dl=0
Another document...
Pre-Illness Data reveals Differences in Multiple Metabolites and Metabolic Pathways in Those Who Do and Do Not Recover from Infectious mononucleosis
https://pubs.rsc.org/en/Content/ArticleLanding/2022/MO/D2MO00124A
Leonard Jason, Karl Conroy, Jacob Furst, Karthik Vasan and Ben Katz...
Full title: Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Who Have Already Visited Some Medical Institutions: The Points of Diagnosis and Treatment
Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a syndrome primarily presenting fatigue-based...
Full title: Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Who Have Already Visited Some Medical Institutions: Diagnosis, Treatment and Research
Abstract
Myalgic encephalitis/chronic fatigue syndrome (ME/CFS) is an acquired intractable disease characterized by...
Abstract
Objectives: Studies have demonstrated immune dysfunction in adolescents with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS); however, evidence is varied. The current study used network analysis to examine relationships between cytokines among a sample of pediatric...
(an old paper, mentioned on another thread here)
Interventions for the Treatment and Management of Chronic Fatigue Syndrome: A Systematic Review
https://jamanetwork.com/journals/jama/article-abstract/194209
Penny Whiting, MSc; 1
Anne-Marie Bagnall, PhD; 1
Amanda J. Sowden, PhD; 1
John E...
Discussion moved from
ME Epidemiology - prevalence, peak ages of onset and gender ratio
Question: what do you think is a reasonable time that passes between an infection and ME/CFS onset?
For some people the ME/CFS symptoms don't start straight away after an infection and there seems to be a...
Statement
My Rt Hon Friend the Secretary of State for Health and Social Care (Sajid Javid) has made the following written statement:
Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) affects the lives of children and adults across the country. It can be an incredibly disabling...
https://osf.io/ef3n4/
The newsbrief posting reminded me that this paper wasn't mentioned. I think it may be a pretty important hypothesis for ME's root cause. It fits what I believe is the root cause of ME: that neuroglia are involved. I'm not sure whether there are any ME symptoms that...
Full title:
CLINICAL IMPROVEMENT IN PATIENTS WITH ME/CFS WITH SYNERGISTIC EFFECT OF COLCHICINE AND SPIRONOLACTONE TARGETING INHIBITION OF INFLAMMASOME ACTIVITY
Dr Jorge do Campo1, Dr Vivienne Taylor2
1Noosa Hospital, Noosaville, Australia, 2Ibuki Medical Centre, Noosa, Australia
Background...
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