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t-cells

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  1. leokitten
    Thread

    Sustained cellular immune dysregulation in individuals recovering from SARS-CoV-2 infection. Files et al. JCI (2020)

    https://www.jci.org/articles/view/140491 SARS-CoV-2 causes a wide spectrum of clinical manifestations and significant mortality. Studies...
    Thread by: leokitten, Dec 29, 2020, 2 replies, in forum: Long Covid research
  2. wigglethemouse
    Thread

    Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease (Jan2020) Gate, M.Davis & Wyss-Coray, Stanford)

    This paper on Alzheimer’s is interesting because Mark Davis (one of the authors) and team are using similar techniques on ME patients to look for...
    Thread by: wigglethemouse, Mar 26, 2020, 1 replies, in forum: Other health news and research
  3. Ravn
    Thread

    Nature: Sex-specific adipose tissue imprinting of regulatory T cells (2020)

    Note: mice. Vasanthakumar, A., Chisanga, D., Blume, J. et al. Sex-specific adipose tissue imprinting of regulatory T cells. Nature (2020)....
    Thread by: Ravn, Feb 28, 2020, 0 replies, in forum: Other health news and research
  4. Sly Saint
    Thread

    T Cell Subpopulations in the Physiopathology of Fibromyalgia: Evidence and Perspectives - Banfi, Diani et al Feb 2020

    Abstract Fibromyalgia is one of the most important “rheumatic” disorders, after osteoarthritis. The etiology of the disease is still not clear. At...
    Thread by: Sly Saint, Feb 12, 2020, 0 replies, in forum: 'Conditions related to ME/CFS' news and research
  5. JohnTheJack
    Thread

    Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo (2020) Nixon et al

    Abstract Long-lasting, latently infected resting CD4+ T cells are the greatest obstacle to obtaining a cure for HIV infection, as these cells can...
    Thread by: JohnTheJack, Jan 23, 2020, 0 replies, in forum: Other health news and research
  6. Dolphin
    Thread

    An investigation into the modulation of T cell phenotypes by amitriptyline and nortriptyline, 2019, Conroy et al

    Possibly of interest, given how many patients can be on these types of drugs. Though I don't really understand what the implications might be...
    Thread by: Dolphin, Dec 28, 2019, 3 replies, in forum: Other health news and research
  7. Ron
    Thread

    ME/CFS patients exhibit altered T cell metabolism and cytokine associations (2019) Mandarano, Hanson et al

    https://www.nih.gov/news-events/news-releases/study-finds-differences-energy-use-immune-cells-me/cfs New findings published in the Journal of...
    Thread by: Ron, Dec 12, 2019, 28 replies, in forum: ME/CFS research
  8. rvallee
    Thread

    First evidence of immune response targeting brain cells in autism

    In a paper published in Annals of Neurology, Matthew Anderson, HMS associate professor of pathology at Beth Israel Deaconess Medical Center, and...
    Thread by: rvallee, Nov 17, 2019, 5 replies, in forum: Other health news and research
  9. Cheshire
    Thread

    ME/CFS as a hyper-regulated immune system driven by an interplay between regulatory T cells & chronic human herpesvirus infections (2019) Nacul et al.

    Nuno Sepúlveda, Jorge Carneiro, Eliana M. Lacerda and Luis C. Nacul Autoimmunity and chronic viral infections are recurrent clinical observations...
    Thread by: Cheshire, Nov 5, 2019, 32 replies, in forum: ME/CFS research
  10. Dolphin
    Thread

    Epstein-Barr virus–specific T cell therapy for progressive multiple sclerosis

    Somebody with ME was excited by this on Twitter https://insight.jci.org/articles/view/124714 Research ArticleClinical trialsNeuroscience Free...
    Thread by: Dolphin, Nov 20, 2018, 9 replies, in forum: Other health news and research
  11. Andy
    Thread

    Associations between clinical symptoms, plasma norepinephrine & deregulated immune gene networks in subgroups of adolescent w/CFS, 2018, Nguyen et al

    Highlights • 29 deregulated immune gene sets were identified to distinguish patients and controls; as well as delineate patients into two...
    Thread by: Andy, Nov 17, 2018, 3 replies, in forum: ME/CFS research
  12. Andy
    Thread

    Tuning of human MAIT cell activation by commensal bacteria species and MR1-dependent T-cell presentation, 2018, Unutmaz et al

    Abstract Human mucosal-associated invariant T (MAIT) cell receptors (TCRs) recognize bacterial riboflavin pathway metabolites through the MHC...
    Thread by: Andy, Oct 8, 2018, 7 replies, in forum: Other health news and research
  13. Milo
    Thread

    Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing (2018)

    Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing Dr Unutmaz is one of the principal investigator of this paper....
    Thread by: Milo, Jul 19, 2018, 0 replies, in forum: Other health news and research
  14. Andy
    Thread

    Lifelong CMV infection improves immune defense in old mice by broadening the mobilized TCR repertoire against third-party infection, 2018, Nikolich

    Obviously based on results from mice, so take any claims with a pinch of salt. Significance Epidemiological studies have shown a correlation...
    Thread by: Andy, Jul 9, 2018, 0 replies, in forum: Other health news and research
  15. Andy
    Thread

    ME Association Ramsay Research Fund invests in new study with ME/CFS Biobank to examine dysfunctional immune system and energy metabolism

    The ME Association is delighted to announce that our Ramsay Research Fund (RRF) will be funding some exciting new research that will further...
    Thread by: Andy, May 15, 2018, 2 replies, in forum: General ME/CFS news
  16. adreno
    Thread

    Successful treatment of POTS and MCAS using LDN, immunoglobulin and antibiotics

    Abstract A patient with severe postural orthostatic tachycardia syndrome (POTS) and mast cell activation syndrome (MCAS) received immunotherapy...
    Thread by: adreno, May 13, 2018, 2 replies, in forum: ME/CFS research
  17. Webdog
    Thread

    Cross-sectional analysis of CD8 T cell immunity to human herpesvirus 6B

    https://doi.org/10.1371/journal.ppat.1006991 Cross-sectional analysis of CD8 T cell immunity to human herpesvirus 6B Larissa K. Martin, Alexandra...
    Thread by: Webdog, Apr 28, 2018, 0 replies, in forum: ME/CFS research
  18. Indigophoton
    Thread

    Association of T and NK cell phenotype with the diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), Rivas et al, 2018

    The paper has been provisionally accepted by Frontiers in Immunology, and the full text is due to be published soon. Myalgic...
    Thread by: Indigophoton, Apr 25, 2018, 10 replies, in forum: ME/CFS research
  19. Andy
    Thread

    Nature News and Views: Killer T cells show their kinder side

    The immune system protects the body by responding to invading organisms. But how is an attack on useful resident microbes prevented? A pathway has...
    Thread by: Andy, Mar 27, 2018, 0 replies, in forum: Other health news and research
  20. Lidia
    Thread

    Advice on these T-cell subsets

    Hi, is anyone able to comment on these T-cell subset results please? Patient is 11yo, first blood was taken 6 weeks after an exacerbation of...
    Thread by: Lidia, Feb 17, 2018, 2 replies, in forum: Immunological
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