PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation Patsoukis N, Bardhan K,...
https://www.mdpi.com/1422-0067/24/3/2010 Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disabling multisystem illness...
SARS-CoV-2 Omicron subvariants evolved to promote further escape from MHC-I recognition Miyu Moriyama, Carolina Lucas, Valter Silva Monteiro, Yale...
Full title: A scoping review of regulatory T cell dynamics in convalescent COVID-19 patients – indications for their potential involvement in the...
I don't know if this has been posted elsewhere but I thought it was very interesting. I wonder if something like this might end up being helpful...
https://www.nature.com/articles/s41586-022-05105-1 Abstract CD8+ T cells that respond to chronic viral infections or cancer are characterized by...
Abstract The gut microbiota encodes a broad range of enzymes capable of synthetizing various metabolites, some of which are still...
https://www.nature.com/articles/s41586-022-05128-8 Anorexia and fasting are host adaptations to acute infection, inducing a metabolic switch...
From: Dr. Marc-Alexander Fluks Source: University of Leeds Date: May 2020, online January 11, 2022 URL:...
Full title: EBV/HHV-6A dUTPases contribute to Myalgic Encephalomyelitis/Chronic-Fatigue-Syndrome pathophysiology by enhancing TFH cell...
Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 Leo Swadling, et al. Individuals with potential exposure to...
From: Dr. Marc-Alexander Fluks Source: University of Oslo Date: May 18 and June 21, 2021 URL:...
Full title: Fine mapping of the major histocompatibility complex (MHC) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggests...
Highlights The magnitude of early CD4+ T cell responses correlates with severity of COVID-19 Prior lung disease correlates with higher...
https://www.biorxiv.org/content/10.1101/2021.06.25.449905v2 The recent COVID-19 pandemic is a treatment challenge in the acute infection stage...
Full title: Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic...
Performed detailed molecular and spatial analysis of the COVID-19 brain immune response Pathognomonic microglial nodules and T cell infiltration...
This post has been copied and following discussion moved from this thread: USA: NIH National Institute of Health The NIH has awarded a $2.5M R01...
https://www.jci.org/articles/view/140491 SARS-CoV-2 causes a wide spectrum of clinical manifestations and significant mortality. Studies...
This paper on Alzheimer’s is interesting because Mark Davis (one of the authors) and team are using similar techniques on ME patients to look for...
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