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t-cells

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  1. rvallee
    Thread

    Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T cell interactions, 2021

    Performed detailed molecular and spatial analysis of the COVID-19 brain immune response Pathognomonic microglial nodules and T cell infiltration...
    Thread by: rvallee, Jun 11, 2021 at 4:25 PM, 2 replies, in forum: Epidemics (including Covid-19)
  2. cassava7
    Thread

    NIH $2.5M R01 grant to Drs Liisa Selin and Anna Gil for their work on altered T cells in ME/CFS, 2021

    This post has been copied and following discussion moved from this thread: USA: NIH National Institute of Health The NIH has awarded a $2.5M R01...
    Thread by: cassava7, Mar 17, 2021, 12 replies, in forum: BioMedical ME/CFS News
  3. leokitten
    Thread

    Sustained cellular immune dysregulation in individuals recovering from SARS-CoV-2 infection. Files et al. JCI (2020)

    https://www.jci.org/articles/view/140491 SARS-CoV-2 causes a wide spectrum of clinical manifestations and significant mortality. Studies...
    Thread by: leokitten, Dec 29, 2020, 2 replies, in forum: Epidemics (including Covid-19)
  4. wigglethemouse
    Thread

    Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease (Jan2020) Gate, M.Davis & Wyss-Coray, Stanford)

    This paper on Alzheimer’s is interesting because Mark Davis (one of the authors) and team are using similar techniques on ME patients to look for...
    Thread by: wigglethemouse, Mar 26, 2020, 1 replies, in forum: Health News and Research unrelated to ME/CFS
  5. Sly Saint
    Thread

    T Cell Subpopulations in the Physiopathology of Fibromyalgia: Evidence and Perspectives - Banfi, Diani et al Feb 2020

    Abstract Fibromyalgia is one of the most important “rheumatic” disorders, after osteoarthritis. The etiology of the disease is still not clear. At...
    Thread by: Sly Saint, Feb 12, 2020, 0 replies, in forum: Health News and Research unrelated to ME/CFS
  6. Ron
    Thread

    ME/CFS patients exhibit altered T cell metabolism and cytokine associations (2019) Mandarano, Hanson et al

    https://www.nih.gov/news-events/news-releases/study-finds-differences-energy-use-immune-cells-me/cfs New findings published in the Journal of...
    Thread by: Ron, Dec 12, 2019, 28 replies, in forum: BioMedical ME/CFS Research
  7. rvallee
    Thread

    First evidence of immune response targeting brain cells in autism

    In a paper published in Annals of Neurology, Matthew Anderson, HMS associate professor of pathology at Beth Israel Deaconess Medical Center, and...
    Thread by: rvallee, Nov 17, 2019, 5 replies, in forum: Health News and Research unrelated to ME/CFS
  8. Cheshire
    Thread

    ME/CFS as a hyper-regulated immune system driven by an interplay between regulatory T cells & chronic human herpesvirus infections (2019) Nacul et al.

    Nuno Sepúlveda, Jorge Carneiro, Eliana M. Lacerda and Luis C. Nacul Autoimmunity and chronic viral infections are recurrent clinical observations...
    Thread by: Cheshire, Nov 5, 2019, 32 replies, in forum: BioMedical ME/CFS Research
  9. Andy
    Thread

    Associations between clinical symptoms, plasma norepinephrine & deregulated immune gene networks in subgroups of adolescent w/CFS, 2018, Nguyen et al

    Highlights • 29 deregulated immune gene sets were identified to distinguish patients and controls; as well as delineate patients into two...
    Thread by: Andy, Nov 17, 2018, 3 replies, in forum: BioMedical ME/CFS Research
  10. Andy
    Thread

    Tuning of human MAIT cell activation by commensal bacteria species and MR1-dependent T-cell presentation, 2018, Unutmaz et al

    Abstract Human mucosal-associated invariant T (MAIT) cell receptors (TCRs) recognize bacterial riboflavin pathway metabolites through the MHC...
    Thread by: Andy, Oct 8, 2018, 7 replies, in forum: Health News and Research unrelated to ME/CFS
  11. Andy
    Thread

    Lifelong CMV infection improves immune defense in old mice by broadening the mobilized TCR repertoire against third-party infection, 2018, Nikolich

    Obviously based on results from mice, so take any claims with a pinch of salt. Significance Epidemiological studies have shown a correlation...
    Thread by: Andy, Jul 9, 2018, 0 replies, in forum: Health News and Research unrelated to ME/CFS
  12. Andy
    Thread

    ME Association Ramsay Research Fund invests in new study with ME/CFS Biobank to examine dysfunctional immune system and energy metabolism

    The ME Association is delighted to announce that our Ramsay Research Fund (RRF) will be funding some exciting new research that will further...
    Thread by: Andy, May 15, 2018, 2 replies, in forum: General ME/CFS News
  13. adreno
    Thread

    Successful treatment of POTS and MCAS using LDN, immunoglobulin and antibiotics

    Abstract A patient with severe postural orthostatic tachycardia syndrome (POTS) and mast cell activation syndrome (MCAS) received immunotherapy...
    Thread by: adreno, May 13, 2018, 2 replies, in forum: BioMedical ME/CFS Research
  14. Webdog
    Thread

    Cross-sectional analysis of CD8 T cell immunity to human herpesvirus 6B

    https://doi.org/10.1371/journal.ppat.1006991 Cross-sectional analysis of CD8 T cell immunity to human herpesvirus 6B Larissa K. Martin, Alexandra...
    Thread by: Webdog, Apr 28, 2018, 0 replies, in forum: BioMedical ME/CFS Research
  15. Indigophoton
    Thread

    Association of T and NK cell phenotype with the diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), Rivas et al, 2018

    The paper has been provisionally accepted by Frontiers in Immunology, and the full text is due to be published soon. Myalgic...
    Thread by: Indigophoton, Apr 25, 2018, 10 replies, in forum: BioMedical ME/CFS Research
  16. Andy
    Thread

    Nature News and Views: Killer T cells show their kinder side

    The immune system protects the body by responding to invading organisms. But how is an attack on useful resident microbes prevented? A pathway has...
    Thread by: Andy, Mar 27, 2018, 0 replies, in forum: Health News and Research unrelated to ME/CFS
  17. Lidia
    Thread

    Advice on these T-cell subsets

    Hi, is anyone able to comment on these T-cell subset results please? Patient is 11yo, first blood was taken 6 weeks after an exacerbation of...
    Thread by: Lidia, Feb 17, 2018, 2 replies, in forum: Immunological
  18. Andy
    Thread

    Genome - Epigenome Interactions Associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2017, McGowan et al

    ABSTRACT Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is an example of a complex disease of unknown etiology. Multiple studies...
    Thread by: Andy, Dec 23, 2017, 1 replies, in forum: BioMedical ME/CFS Research
  19. Andy
    Thread

    A Gut Microbial Mimic that Hijacks Diabetogenic Autoreactivity to Suppress Colitis, 2017, McCoy et al

    Highlights •The Bacteroides integrase encodes a low-avidity mimotope of IGRP206-214 •The microbial epitope recruits diabetogenic CD8+ T cells to...
    Thread by: Andy, Dec 8, 2017, 1 replies, in forum: Health News and Research unrelated to ME/CFS
  20. Dolphin
    Thread

    Severity of Acute Infectious Mononucleosis Correlates with Cross-Reactive Influenza CD8 T-Cell Receptor Repertoires Nuray Aslan et al 2017

    http://mbio.asm.org/content/8/6/e01841-17 Severity of Acute Infectious Mononucleosis Correlates with Cross-Reactive Influenza CD8 T-Cell Receptor...
    Thread by: Dolphin, Dec 7, 2017, 10 replies, in forum: Health News and Research unrelated to ME/CFS
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