t cells

  1. R

    Autoimmunity-Related Risk Variants in PTPN22 and CTLA4 Are Associated With ME/CFS With Infectious Onset (2020) Scheibenbogen et al.

    https://www.frontiersin.org/articles/10.3389/fimmu.2020.00578/full Excerpt: In conclusion, our study shows that the PTPN22 rs2476601 and CTLA4 rs3087243 autoimmunity risk variants are more frequent in patients with ITO ME/CFS. This finding provides further evidence that there is a genetic...
    • Ron
    • Thread
    • 2020 autoimmunity b cells genetics me/cfs paper pathogenesis scheibenbogen steiner t cells
    • Replies: 10
    • Forum: ME/CFS research
  2. Dolphin

    Role of immune responses, focussing on herpes virus specificity and interferon-gamma, in Myocardial Infarction with reperfusion & in CFS, 2019, Murali

    • Dolphin
    • Thread
    • 2019 cmv cytokines ebv herpesvirus me/cfs murali myocardial paper t cells
    • Replies: 0
    • Forum: ME/CFS research
  3. Sly Saint

    BIOMARKER FOR MYALGIC ENCEPHALOMYELITIS/CHRONIC FATIGUE SYNDROME (ME/CFS) - Yamamoto et al 27 Feb 2020

    https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2020040210&tab=PCTBIBLIO (main paper in japanese)
    • Sly Saint
    • Thread
    • 2020 b cells biomarker iggr me/cfs paper t cells yamamoto
    • Replies: 6
    • Forum: ME/CFS research
  4. Andy

    T cell immunomodulation by bile acid metabolites, 2020, Giovannini et al

    A short review/opinion piece. Paywall, https://onlinelibrary.wiley.com/doi/pdf/10.1111/all.14223 Sci hub, https://sci-hub.se/10.1111/all.14223 @mariovitali , another one that will probably interest you. :)
  5. Sly Saint

    Myalgic encephalomyelitis/chronic fatigue syndrome patients exhibit altered T cell metabolism and cytokine associations - [new article 2020]

    Basal glycolysis is reduced in ME/CFS CD4+ T cells. https://www.jci.org/articles/view/132185/figure/4 paper from December 2019 https://www.jci.org/articles/view/132185 new Article by Mady Hornig https://www.jci.org/articles/view/134985
    • Sly Saint
    • Thread
    • 2020 article cytokines glycolysis hornig me/cfs metabolism paper t cells
    • Replies: 5
    • Forum: ME/CFS research
  6. Andy

    Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis, 2019, Song et al

    In mice. Paywall, https://www.nature.com/articles/s41586-019-1865-0 Sci hub, https://sci-hub.se/10.1038/s41586-019-1865-0 ETA: Added "In mice".
  7. Andy

    Bile acid metabolites control TH17 and Treg cell differentiation, 2019, Hang et al

    In mice. Paywall, https://www.nature.com/articles/s41586-019-1785-z Sci hub, https://sci-hub.se/10.1038/s41586-019-1785-z
  8. Hoopoe

    Perturbation of effector and regulatory T cell subsets in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (2019) Karhan, Unutmaz et al

    Moderator note: See this post in the thread for the preprint.
    • Hoopoe
    • Thread
    • 2019 biomarker intestinal permeability jackson labs leaky gut mait cells me/cfs microbiome paper t cells unutmaz zonulin
    • Replies: 90
    • Forum: ME/CFS research
  9. Sly Saint

    ME/CFS Research Update: November 2019 Bedside Chat with Ben H. and Ron Davis

    thanks to @Ben H eta: youtube generated transcript pt 1
    • Sly Saint
    • Thread
    • 2019 cci clonal expansion me/cfs omf red blood cell deformability research ron davis t cells trypanosome video
    • Replies: 2
    • Forum: ME/CFS research
  10. Cheshire

    Cellular immune function in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) (2019) Cliff, Nacul et al.

    https://www.frontiersin.org/articles/10.3389/fimmu.2019.00796/abstract Full, open access, text here, https://www.frontiersin.org/articles/10.3389/fimmu.2019.00796/full ETA: Link to full text.
    • Cheshire
    • Thread
    • 2019 immunology me/cfs monocytes nacul natural killer cells paper t cells
    • Replies: 11
    • Forum: ME/CFS research
  11. Andy

    Mitochondrial complex III is essential for suppressive function of regulatory T cells, 2019, Chandel et al

    Open access (PDF file) at https://www.nature.com/articles/s41586-018-0846-z.epdf?shared_access_token=WAkCBVS3L3DO0bM6CbjKJ9RgN0jAjWel9jnR3ZoTv0NUSr5JeVHn5ILb4ngHL_BsTJMx2GJRjntjSBzshFZ8yE4tC3l6CzSLy6_zVux-gc6CNyCRZyfQaZAXy__EeJqkVjgWHo5q5hftEAvdjdhYIjKN3PqYRuicN1bmJ64vvgs%3D
  12. Webdog

    GDP-l-fucose synthase is a CD4+ T cell–specific autoantigen in DRB3*02:02 patients with multiple sclerosis (2018) Planas et al

    Study: GDP-l-fucose synthase is a CD4+ T cell–specific autoantigen in DRB3*02:02 patients with multiple sclerosis http://stm.sciencemag.org/content/10/462/eaat4301 Press Release: Link between gut flora and multiple sclerosis discovered https://www.sciencedaily.com/releases/2018/10/181011103636.htm
  13. Snowdrop

    Deficient EBV-Specific B and T-cell response in patients with CFS, 2014, Loebel et al.

    Have no idea of what any of this means. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085387 Hope it's of some interest.
    • Snowdrop
    • Thread
    • 2014 b cells ebv immunology loebel me/cfs paper t cells
    • Replies: 1
    • Forum: ME/CFS research
  14. Webdog

    Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis (2018) Jelcic et al

    Study: Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis https://www.sciencedirect.com/science/article/pii/S0092867418310274 News Article: How B-cells Work to Promote T-cell Attacks on Myelin That Lead to MS Detailed in Study...
  15. Indigophoton

    JAX Research Highlight: Immune system 2.0: Can we re-engineer the human immune response?

    https://www.jax.org/news-and-insights/2018/july/human-immune-response#
  16. Indigophoton

    The immune system: T cells are built for speed

    https://medicalxpress.com/news/2018-07-immune-cells-built.amp
  17. Indigophoton

    T cell engineering breakthrough sidesteps need for viruses in gene-editing

    https://phys.org/news/2018-07-cell-breakthrough-sidesteps-viruses-gene-editing.amp
  18. Indigophoton

    Immune cells can switch from ‘gang members’ to ‘police officers’

    https://www.imperial.ac.uk/news/187131/immune-cells-switch-from-gang-members/
  19. Indigophoton

    Ron Davis: Grant award: Molecular and single-cell immunology in ME/CFS

    Ron Davis has been awarded several million dollars by the US National Institute of Allergy and Infectious Diseases to "uncover the immunological basis of ME" by examining T cell activity and related genetic factors, and by hunting for pathogens. The project start date is this month, and the end...
  20. Indigophoton

    Tracking peripheral immune cell infiltration of the brain in ME

    Very interesting sounding project from Jarred Younger, http://www.meresearch.org.uk/our-research/ongoing-studies/immune-cell-infiltration/
    • Indigophoton
    • Thread
    • immunology jarred younger microglia neuroinflammation neurology t cells
    • Replies: 1
    • Forum: ME/CFS research
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