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t cells
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Preprint Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping, 2024, Wang, Iwasaki+
Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping Hospitalized COVID-19 patients exhibit diverse immune responses during acute infection, which are associated with a wide range of clinical outcomes. However, understanding these immune heterogeneities...- SNT Gatchaman
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- coagulation complement inflammation t cells
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- Forum: Long Covid research
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[NF-κB], interferon regulatory Factor, and glucocorticoid receptor pathway activation in [depression]: The role of [CMV], 2024, Savitz+
Nuclear factor kappa-B cell NF-κB, interferon regulatory Factor, and glucocorticoid receptor pathway activation in major depressive Disorder: The role of cytomegalovirus infection Savitz; McKinney; Meier; Zheng; Ford; Yolken; Teague; Cole Altered activity of major immunoregulatory pathways has...- SNT Gatchaman
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- cmv depression glucocorticoid receptor interferon monocytes nf-κb t cells
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- Forum: Other health news and research
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Maternal COVID-19 infection associated with offspring neurodevelopmental disorders, 2024, Duan et al.
Maternal COVID-19 infection associated with offspring neurodevelopmental disorders Duan, Lian; Yin, Huamin; Liu, Jiaxin; Wang, Wenhang; Huang, Peijun; Liu, Li; Shen, Jingling; Wang, Zhendong Maternal COVID-19 infection increases the incidence of neurodevelopmental disorders (NDDs) in offspring...- SNT Gatchaman
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- astrocytes endothelial cells fetus neurodevelopmental delay neurons t cells
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- Forum: Long Covid research
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Immunometabolic changes and potential biomarkers in CFS peripheral immune cells revealed by single-cell RNA sequencing, 2024, Sun et al
Abstract The pathogenesis of Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) remains unclear, though increasing evidence suggests inflammatory processes play key roles. In this study, single-cell RNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs) was used to...- Wyva
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- 2024 amyloid amyloid precursor protein biomarker cd74 china cytoskeleton esrra hla hla-dqb1 immune dysregulation integrated stress response nk cells oestrogen pbmc resistin single-cell rna-sequencing t cells
- Replies: 26
- Forum: ME/CFS research
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SARS-CoV-2-specific CD8+ T cells from people with [LC] establish and maintain effector phenotype and key TCR signatures over 2 years, 2024, Rowntree+
SARS-CoV-2-specific CD8+ T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years Rowntree, Louise C.; Audsley, Jennifer; Allen, Lilith F.; McQuilten, Hayley A.; Hagen, Ruth R.; Chaurasia, Priyanka; Petersen, Jan; Littler, Dene R.; Tan...- SNT Gatchaman
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- b cells hla t cell receptor t cells vaccination
- Replies: 4
- Forum: Long Covid research
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An aberrant immune–epithelial progenitor niche drives viral lung sequelae, 2024, Narasimhan et al.
An aberrant immune–epithelial progenitor niche drives viral lung sequelae Narasimhan, Harish; Cheon, In Su; Qian, Wei; Hu, Sheng’en Shawn; Parimon, Tanyalak; Li, Chaofan; Goplen, Nick; Wu, Yue; Wei, Xiaoqin; Son, Young Min; Fink, Elizabeth; de Almeida Santos, Gislane; Tang, Jinyi; Yao, Changfu...- SNT Gatchaman
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- il-1b interferon macrophages t cells tnf
- Replies: 2
- Forum: Long Covid research
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Epigenetic patterns, accelerated biological aging, and enhanced epigenetic drift detected 6 months following C-19 infection: genome-wide DNA study
Epigenetic patterns, accelerated biological aging, and enhanced epigenetic: drift detected 6 months following COVID-19 infection: insights from a genome-wide DNA methylation study, 2024, Calzari Luciano, Dragani Davide Fernando et al Abstract Background The epigenetic status of patients 6-month...- Mij
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- apoptosis endothelin epigenetics glutamate glutamine hif-1 insulin t cells vegf
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- Forum: Long Covid research
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The longitudinal characterization of immune responses … reveals novel prognostic signatures for disease severity [& LC], 2024, Noviello+
The longitudinal characterization of immune responses in COVID-19 patients reveals novel prognostic signatures for disease severity, patients’ survival and long COVID Noviello, Maddalena; De Lorenzo, Rebecca; Chimienti, Raniero; Maugeri, Norma; De Lalla, Claudia; Siracusano, Gabriel; Lorè...- SNT Gatchaman
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- b cells immune monocytes mortality nk cells nkg2a t cells
- Replies: 0
- Forum: Long Covid research
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Bioinformatic analysis predicts the regulatory function of noncoding SNPs associated with Long COVID-19 syndrome, 2024, Maiti, Amit K.
Bioinformatic analysis predicts the regulatory function of noncoding SNPs associated with Long COVID-19 syndrome Maiti, Amit K. Long or Post COVID-19 is a condition of collected symptoms persisted after recovery from COVID-19. Host genetic factors play a crucial role in developing Long...- SNT Gatchaman
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- bioinformatics epigenetics gwas long covid monocytes snp t cells
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- Forum: Long Covid research
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Sex differences and immune correlates of Long COVID development, persistence, and resolution, 2024, Hamlin et al.
Sex differences and immune correlates of Long COVID development, persistence, and resolution Rebecca E Hamlin; Shaun M Pienkos; Leslie Chan; Mikayla A Stabile; Kassandra Pinedo; Mallika Rao; Philip Grant; Hector Bonilla; Marisa Holubar; Upinder Singh; Karen B Jacobson; Prasanna Jagannathan...- SNT Gatchaman
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- ets1 integrins interferon interferon-y monocytes nf-κb nk cells sex differences t cells tgf-beta
- Replies: 7
- Forum: Long Covid research
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Diverse immunological dysregulation, chronic inflammation, and impaired erythropoiesis in long COVID patients with chronic fatigue syndrome, 2024
Diverse immunological dysregulation, chronic inflammation, and impaired erythropoiesis in long COVID patients with chronic fatigue syndrome Saito; Shahbaz; Osman; Redmond; Bozorgmehr; Rosychuk; Lam; Sligl; Cohen Tervaert; Elahi A substantial number of patients recovering from acute SARS-CoV-2...- SNT Gatchaman
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- artemin galectin t cells tgf-beta
- Replies: 7
- Forum: Long Covid research
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Online: Renegade Research 'Research Roundtable', T cell dysfunction in ME/CFS seminar, May 23rd 2024
Our next @RenegadeRes Research roundtable is Thursday May 23rd. The topic is "T-cell dysfunction in #MECFS and #LongCovid " with researchers Liisa K. Selin, MD PhD; Anna Gil, PhD, viral immunologists from the University of Massachusetts Chan Medical School Roshan Kumar, PhD,… Show more...- Jaybee00
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- gil selin t cells
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- Forum: ME/CFS research news
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Preprint Persistent Activation of Chronic Inflammatory Pathways in Long Covid, 2024, Aid et al.
Persistent Activation of Chronic Inflammatory Pathways in Long Covid Malika Aid; Katherine McMahan; Nicole Hachmann; Jessica Miller; Erica Borducchi; David Hope; Marjorie Rowe; Eleanor Schonberg; Siline Thai; Ai-ris Collier; Janet Mullington; Dan Barouch Long Covid, or Post-Acute Sequelae of...- SNT Gatchaman
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- coagulation complement hla-dqb1 inflammation insulin jak-stat lipids mast cells nk cells t cells
- Replies: 4
- Forum: Long Covid research
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Preprint Oxidative Stress is a shared characteristic of ME/CFS and Long COVID, 2024, Shankar, Bonilla, Davis et al.
Oxidative Stress is a shared characteristic of ME/CFS and Long COVID Vishnu Shankar; Julie Wilhelmy; Basil Michael; Layla Cervantes; Vamsee Mallajosyula; Ronald Davis; Michael Snyder; Shady Younis; William H Robinson; Sadasivan Shankar; Paul Mischel; Hector Bonilla; Mark Davis More than 65...- SNT Gatchaman
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- calcium glutathione gpx4 lipid droplets lipids mark davis metformin mitochondria oxidative stress reactive oxygen species ron davis sex differences t cells
- Replies: 37
- Forum: ME/CFS research
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T cells in health and disease Sun et al 2023
https://www.nature.com/articles/s41392-023-01471-y Very long article Abstract T cells are crucial for immune functions to maintain health and prevent disease. T cell development occurs in a stepwise process in the thymus and mainly generates CD4+ and CD8+ T cell subsets. Upon antigen...- Jaybee00
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- t cells
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- Forum: 'Conditions related to ME/CFS' news and research
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Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection, Matthews et al, 2024
n=31 Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection Abstract This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long COVID (LC)...- John Mac
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- cd4+ cd8+ ifny immune dysregulation long covid pd-1 recovery rates t cells tim-3
- Replies: 4
- Forum: Long Covid research
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Review Systems analysis of innate and adaptive immunity in Long COVID, 2024, Peluso et al.
Systems analysis of innate and adaptive immunity in Long COVID Peluso; Abdel-Mohsen; Henrich; Roan Since the onset of the COVID-19 pandemic, significant progress has been made in developing effective preventive and therapeutic strategies against severe acute SARS-CoV-2 infection. However, the...- SNT Gatchaman
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- b cells immune system immunoglobulin innate immune system long covid system biology t cells
- Replies: 2
- Forum: Long Covid research
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Preprint Sex differences in symptomatology and immune profiles of Long COVID, 2024, Silva, Putrino, Iwasaki et al.
Sex differences in symptomatology and immune profiles of Long COVID Julio Silva; Takehiro Takahashi; Jamie Wood; Peiwen Lu; Sasha Tabachnikova; Jeffrey Gehlhausen; Kerrie Greene; Bornali Bhattacharjee; Valter Silva Monteiro; Carolina Lucas; Rahul Dhodapkar; Laura Tabacof; Mario Pena-Hernandez...- SNT Gatchaman
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- april cmv complement cortisol dendritic cells ebv endocrine endocrine regulation hsv2 immune system interferon long covid monocytes nk cells oestrogen sex differences t cells testosterone
- Replies: 2
- Forum: Long Covid research
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Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment, 2024, Greene et al
Preprint Blood-brain barrier disruption in Long COVID-associated cognitive impairment Chris Greene, Ruairi Connolly, Declan Brennan, Aoife Laffan, Eoin O'Keeffe, Lilia Zaporojan, Emma Connolly, Cliona Ni Cheallaigh, Niall Conlon, Colin Doherty, Matthew Campbell Vascular disruption has been...- SNT Gatchaman
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- brain imaging coagulation csf dce-mri endothelial gfap icam-1 inflammation long covid long covid clinic mri p-selectin pf4 platelets s100 scam-1 spike protein t cells tgf-beta tnf
- Replies: 44
- Forum: Long Covid research
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Preprint Restrained memory CD8+ T cell responses favors viral persistence and elevated IgG responses in patients with severe Long COVID., 2024, Rodriguez et al
Restrained memory CD8+ T cell responses favors viral persistence and elevated IgG responses in patients with severe Long COVID. Lucie Rodriguez; Ziyang Tan; Lakshmi Kanth Tadepally; Jun Wang; Hugo Barcenilla; Zoe Swank; Fanglei Zuo; Hassan Abolhassani; Ana Jimena Pavlovitch-Bedzyk; Chunlin Wang...- SNT Gatchaman
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- cd8 endopat interferon long covid t cell clonal expansion t cells
- Replies: 4
- Forum: Long Covid research