Pure speculation but maybe this line of research or the methods used in the paper to understand immune cell metabolic reprogramming via...
https://www.frontiersin.org/articles/10.3389/fimmu.2021.700782/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE...
This thread was split from Open Medicine Foundation (OMF) News It is certainly true that not all autoimmune disease show useful benefit from...
Full title: Brain astrocytes and microglia express functional MR1 molecules that present microbial antigens to mucosal-associated invariant T...
Full title: Immunometabolic profiling of T cells from patients with relapsing-remitting multiple sclerosis reveals an impairment in glycolysis and...
https://www.frontiersin.org/articles/10.3389/fimmu.2020.00578/full Excerpt: In conclusion, our study shows that the PTPN22 rs2476601 and CTLA4...
The role of immune responses, focussing on herpes virus specificity and interferon-gamma, in Myocardial Infarction with reperfusion and in Chronic...
Abstract (EN) A method for diagnosing myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is provided in the present disclosure. The...
Basal glycolysis is reduced in ME/CFS CD4+ T cells. https://www.jci.org/articles/view/132185/figure/4 paper from December 2019...
[MEDIA] Moderator note: See this post in the thread for the preprint.
[MEDIA] thanks to @Ben H eta: youtube generated transcript pt 1 01:11 them so um I guess to start it off I 01:14 just wanted to say to talk...
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating condition with unknown aetiology, unclear pathophysiology and with...
Abstract Regulatory T cells (Treg cells), a distinct subset of CD4+ T cells, are necessary for the maintenance of immune self-tolerance and...
Study: GDP-l-fucose synthase is a CD4+ T cell–specific autoantigen in DRB3*02:02 patients with multiple sclerosis...
Have no idea of what any of this means. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085387 Hope it's of some interest.
Study: Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis...
[IMG] Genetic editing has progressed rapidly over the past several years, in large part because of the development and refinement of CRISPR/Cas9...
Without T cells, we could not survive. They are a key component of the immune system and have highly sensitive receptors on their surface that can...
In an achievement that has significant implications for research, medicine, and industry, UC San Francisco scientists have genetically...
[IMG] T cells (green) and regulatory T cells (red) [IMG] When the immune system overreacts, as in an allergic reaction, cells causing trouble can...
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