pem

https://mro.massey.ac.nz/bitstream/handle/10179/14653/02_whole.pdf?sequence=2&isAllowed=y New Zealand study of PEM using 2xCPETs at 48 or 72 hours. ABSTRACT PURPOSE: To investigate the timeline of post-exertional malaise (PEM) using objective and subjective measures in Myalgic...

A study that is of interest because it measured activity levels with an accelerometer. https://www.ncbi.nlm.nih.gov/pubmed/22032215 Unfortunately the authors did not investigate further to find out the "direction of these relations".

https://www.meassociation.org.uk/wp-content/uploads/MEA-Research-Review-Assessing-PEM-in-MECFS-25.03.19.pdf 14 page pdf document that covers definitions of PEM, clinical assessment and management including heart rate monitoring, and the latest research.

Abstract Myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) is a syndrome of unknown etiology characterized by profound fatigue exacerbated by physical activity, also known as post-exertional malaise (PEM). Previously, we did not detect evidence of immune dysregulation or virus...

Do you get post-exertional malaise (PEM) from going outdoors, not related to exercise? If so, do you know what causes it in your case? I've tried to reduce all the triggers of PEM I could think of when going outside, but I still get PEM. The possible triggers and solutions I've tried...

New study on PEM by the research team of Leonard Jason. I'm sure many on this forum will have filled in the online questionnaire:

The Norwegian Institute of Public Health has today published a literature search about PEM. The Norwegian ME Association asked them to make an overview of research on PEM in ME in 2015. The literature search was done in February 2019 by Lillebeth Larun (from the contested Cochrane review on ME...

A note for those who use sleep medication to help combat ME sleep issues - this might be more difficult to answer since the body becomes somewhat dependent on medication when taken chronically. If you could try to answer based on your time with ME before you ever took sleep meds or, if that is...

This new thread has been split from this thread. A Members Only thread also has relevant content. oh hallelujah. I've been thinking for years that how can any of it be of any proper use until we are really clear on what it is we're studying, especially re PEM. I think this is the only way to...

Slightly confused, as Lenny Jason is saying that this was just published when the journal webpage says first published 2016, so I went with the journal. Paywalled at https://journals.sagepub.com/doi/full/10.1177/1359105316664139

One of the most debilitating aspects of my ME is that the disease causes me major sleep inversion. On most evenings, after significant enough exertion builds up from the previous day(s), I primarily get a very strong brain wired-but-tired feeling and my gut starts becoming irritated. I also...

https://www.meaction.net/2019/01/07/nih-pem-focus-group/

https://anzmes.org.nz/looking-for-participants-for-a-research-study-on-the-effects-of-exercise-at-anaerobic-threshold-on-post-exertional-malaise-in-individuals-with-me-cfs/

At the other place I started a thread (Feeling very heavy - symptom that rarely gets mentioned) with this post: " I have come across anecdotal mention of this symptom but never seen it included in any diagnostic criteria I can remember. It is something that I regularly experience a lot...

From 2015 but I only read it recently: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295644/

http://journals.sagepub.com/doi/abs/10.1177/1359105318805819?journalCode=hpqa

Dr Alan Moreau presented preliminary results of his work on micro-RNAs (miRNA) at the recent Stanford (2:26) and CMRC conferences. Micro-RNAs are small molecules that regulate gene expression by binding to messenger RNA and blocking their translation into proteins. miRNAs might be new to you and...

now seems like a good time to post this. had it for a while but seid etc. are popping up. has the following idea been ruled out? === pem, pene (meicc) and exertion intolerance (iom) seem to refer to exertion causing crashes. sometimes it is claimed that if you do not have it, then you do not...

I was playing around with a medical dictionary to try and come up with an alternative for 'fatigue' which is more or less the common denominator in all ME/CFS diagnostic criteria. Note: I was not trying to invent a new name for the illness! Anyway, having come up with a couple I thought I'd...

Once I get truly exhausted, my throat starts to hurt (whether or not I've been talking a lot). It starts to feel dry and my speaking grows hoarse. If I continue speaking (in a meeting, what-have-you) I start to feel like I'm going to throw up. Eventually it becomes overwhelming and I have to...