pem

Moderator note: This post has been copied and following posts moved from this thread: Epidemiological and clinical factors associated with post-exertional malaise severity in patients with ME/CFS. Ghali et al. 2020 ____________________ PEM studies always catch my attention, especially ones...

Paywall, https://content.iospress.com/articles/work/wor203168 Sci hub, https://sci-hub.tw/10.3233/WOR-203168

Several threads have been merged ME-conferences in Sweden Oct 17th and 18th 2018 RME, the Swedish patient organisation, invites once again to two conferences about ME this autumn. Some of the programme is in English, and some in Swedish. (I have translated the Swedish parts for this post)...

Sponsor Vrije Universiteit Brussel Overall contact Andrea Polli, MSc full details here: https://www.smartpatients.com/trials/NCT04378634

Today is the première of the English version of a three minute long film about ME and PEM. It's made by the Norwegian ME Association - Rogaland County with professional help from psychologist Ketil Jakobsen and paediatric neurologist Kristian Sommerfelt. The film is available for everyone to...

A Canadian study https://www.jpsmjournal.com/article/S0885-3924(20)30098-1/fulltext?rss=yes

Topic Post-Exertional Malaise: Identifying, Understanding and Preventing Description Post-exertional malaise (PEM) is the hallmark clinical feature of ME/CFS. The webinar will present research that advances our understanding of this important complex of symptoms and introduce a timecourse for...

The video from the Action CIND webinar on Dec. 11th, featuring speakers from Workwell Foundation, is now available on vimeo (about 1 1/2 hours long). Why Working out Doesn’t Work. Answers from 20 years of cardiopulmonary exercise testing (CPET) in ME/CFS I don't think the video will play if...

https://www.sciencedirect.com/science/article/abs/pii/S0022399919304672

Action CIND https://zoom.us/webinar/register/WN_v41HUQKxRPKhRTncHHVUoQ?fbclid=IwAR1EFCcuYq4Fv2zbMStETnfEaHVwQ8QFACmWT-mIz77l0I7DbyTNkfshj6Q eta: Dec 19, 2019 02:00 PM in Eastern Time (US and Canada)

full paper https://www.nature.com/articles/s41598-019-55473-4

https://www.sciencedirect.com/science/article/abs/pii/S0167876019305495

So one challenge that I believe we face is that if most, if not all, research studies insist on PEM as part of the inclusion criteria, we run the risk of mild sufferers not recognising PEM for what it is. For example, CCC description of PEM and ICC description of PENE I would not have...

Paywall, https://www.tandfonline.com/doi/abs/10.1080/21641846.2019.1687117 Not available via Scihub at time of posting

Wondering if PEM itself contributes to POTS. I remember reading Prof Neil McGregor's studies showing PEM involves a hypermetabolic state where we urinate out metabolites. Does anyone know if this contributes to orthostatic intolerance / lowered blood volume?

I was browsing research and noticed that some harmful effects of hypoxia on the brain are delayed by days or even a week. The affected person appears to recover from the immediate effects but then has a delayed and marked worsening of brain health. This is in cases of major hypoxic brain damage...

So, I'm sure many of us are familiar with the idea of establishing an activity baseline, which is where the activity that you are able to manage doesn't trigger PEM. I would argue though that the concept of a baseline is inherently dangerous for PwME as it implies a position that can then be...

Open access at https://www.mdpi.com/2075-4418/9/3/70

I have seen some discussions here and there around the puzzling fact of muscle pain being a consequence of neural exhaustion, whatever that actually means in pathophysiology, but not within a formal thread. It's not quite clear how much distinction there is between PEM and PENE. Maybe they are...

I’ve previously considered myself to be unlikely to have POTS. I can be almost normally active on very good days (paid for later). But a recent experience of tachycardia (110-135bpm when normal resting was 58-70) for days on end, and repeated instances in the days before and after that of...