A hierarchical logistic regression predicting rapid respiratory rates from post-exertional malaise. Jason et al. 2020

https://www.tandfonline.com/doi/abs/10.1080/21641846.2020.1845287

 

That potentially makes it the largest ever sample of mecfs peeps who have had a CPET. I would love to see The results for such a large sample. So far we’ve had a lot of small studies: what we need are large studies, or good meta analyses of small ones.

 

This is from 12 May 2020, but I think I have seen it mentioned again in recent weeks (delayed due to Covid).

https://meassociation.org.uk/2020/0...-changes-in-daily-activity-in-me-12-may-2020/

In the ‘interview’ - Dr Clague-Baker of @PhysiosforME says that she hopes this feasibility study will proceed to a much larger study and that they can apply for funding from the NIHR.

 

That looks like a different study.

The authors of this study are:

Notes on contributors
Joseph Cotler is a project director of ME/CFS research at the Center for Community Research at DePaul university. He has been conducting research on ME/CFS since 2018.

Dr Ben Z. Katz is a Professor of Pediatrics at the Northwestern University Feinberg School of Medicine and an Attending Physician in the Division of Infectious Diseases at the Ann & Robert H Lurie Children’s Hospital of Chicago. He has been studying chronic fatigue syndrome with the group from DePaul since 2002.

Corine Reurts-Post is a doctor’s research assistant at the CVS/ME Medisch Centrum in Amsterdam, specializing in the treatment of patients with chronic fatigue.

Ruud Vermeulen heads the Research department and the research and treatment of chronic fatigue and exercise physiology at the CVS/ME Medisch Centrum.

Leonard A. Jason has been the principle investigator of ME/CFS research at DePaul university and the Center for Community Research for 25 years.

 

This study looks pretty interesting as it addresses the psychiatric/biological cause with a large group of adult patients (as Simon noted). I don't know when I'll be able to read it, but I got a little confused by the prepositional phrase regarded PEM which can be easily misread as PEM is a symptom of me/cfs *and* psychiatric/somatic symptoms.

Although, I must admit I can't remember ever hyperventilating. It seems possible I might cross the thresshold of 20 breaths in minute when it's driven by tachycardia, a more common symptom of mine.

 

Full paper available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610439/