Post Exertional Malaise is the hallmark symptom of #MECFS and is also common in #LongCovid.
Video explains the abnormal response to exertion, triggers, symptoms and management.
BACKGROUND:
Existing instruments often are inappropriate to measure the effects of post-exertional malaise (PEM) and post-exertional symptom exacerbation (PESE) on activities of daily living (ADLs). A validated questionnaire to measure self-reported ability with ADLs would advance research and...
This description in a paper on sarcoidosis sounds like PEM (although not much detail is given so it's not clear).
In this study they also performed repeated CPET and found "no impairment of maximal exercise testing" on the second test...
I'm new to an ME diagnosis (got it Dec 27, 2022, although I'd had ME symptoms since 1994 if not before) but not new to cardiac issues. I've had lots of testing as a result of chest pain while exercising (nothing wrong with my heart; in retrospect an ME symptom related to pushing myself too hard)...
Kujawski, Julia Newton et al
Abstract
Post-exertional malaise (PEM) is regarded as the hallmark symptom in chronic fatigue syndrome (CFS). The aim of the current study is to explore differences in CFS patients with and without PEM in indicators of aortic stiffness, autonomic nervous system...
Podcast episode about PEM, well worth a listen :thumbsup:
https://natashalipman.substack.com/p/post-exertional-malaise
Transcript here:
http://natashalipman.com/post-exertional-malaise-podcast-transcript
ME/CFS and Post-Exertional Malaise among Patients with Long COVID
by Leonard A. Jason and Joseph A. Dorri
Abstract
This study sought to ascertain the prevalence of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) among a sample of 465 patients with Long COVID. The participants...
Full title: Fatigue, post-exertional malaise and orthostatic intolerance: a map of Cochrane evidence relevant to rehabilitation for people with post COVID-19 condition
INTRODUCTION: Rehabilitation focuses on impairments, activity limitations and participation restrictions being informed by the...
Full title: Effect of using a structured pacing protocol on post-exertional symptom exacerbation and health status in a longitudinal cohort with the post-COVID-19 syndrome
Background
Post Exertional Symptom Exacerbation (PESE) is a characteristic symptom of Post-COVID Syndrome (PCS)...
From OMF news email
Post Exertion Malaise (PEM): Dr. David Systrom Aims to Fill in Gaps
Today we are pleased to highlight one of the studies included in our 2022 OMF supported research initiatives! Remember, when you give this November, your gift will be TRIPLED by generous donors. Hurry before...
Unravelling the nature of postexertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome: the role of elastase, complement C4a and interleukin-1β
Abstract
Abstract. Nijs J, Van Oosterwijck J, Meeus M, Lambrecht L, Metzger K, Frémont M, Paul L (Vrije Universiteit Brussel...
About: Graded exercise is commonly prescribed after illness to improve symptoms and functional tolerance. Protracted and limited courses of recovery may be associated with post-exertional symptom exacerbation (PESE), which is common after many other forms of viral and bacterial infection...
Hi All,
It's be really interested in what people's thoughts are for the most accurate fatigue scales that can be used in research studies?
Ones that also give representation to PEM over time.
The CFQ (chalder fatigue scale/ questionnaire) is often used but has serious limitations.
The DePaul...
This idea has come up before and I thought it would be interesting to write down some of my thoughts on this. Housekeeing processes have a role in keeping cells healthy by doing things such as maintaining structural integrity and degrading and recycling intracellular components (like...
Abstract
Background People with Long Covid (Post-Acute Sequelae of Covid-19) describe multiple symptoms which vary between and within individuals over relatively short time intervals. We aimed to describe the real-time associations between different symptoms and between symptoms and physical...
JCI Insight
Plasma metabolomics reveals disrupted response and recovery following maximal exercise in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Abstract
Post-exertional malaise (PEM) is a hallmark symptom of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).
We monitored...
Thread split from UK NICE 2021 ME/CFS Guideline, published 29th October - post-publication discussion
For those who want to share personal experiences on this topic less publicly there is a thread in the members only area here.
______________
I used to think it was unique. But I am starting...
Just one of these things I have tumbling around in the back of my head for a while now, and I was curious about your opinion.
One of the key characteristics of ME/CFS is that you are limited in what you can do, there is an "energy envelope" that is markedly smaller than pre-illness. You can...
Bateman Horne Center
· RELEASED: "ME/CFS Crash Survival Guidebook: The Art of Living with ME/CFS" https://bit.ly/34nh5yX
The guidebook is designed for the patient, their support network, and medical providers to:
- Understand ME/CFS and its defining characteristic of post-exertional malaise...
Lessons from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome for Long COVID: Postexertional Symptom Exacerbations is an Abnormal Response to Exercise/Activity
Authors: Todd E. Davenport, Staci R. Stevens, Jared Stevens, Christopher R. Snell, J. Mark Van Ness
Quote:
Prolonged symptoms after...
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