pem

  1. Adam pwme

    New video: PEM (2 mins)

    Post Exertional Malaise is the hallmark symptom of #MECFS and is also common in #LongCovid. Video explains the abnormal response to exertion, triggers, symptoms and management.
  2. Andy

    Development and measurement properties of the PEM/PESE activity questionnaire (PAQ), 2023, Davenport et al

    BACKGROUND: Existing instruments often are inappropriate to measure the effects of post-exertional malaise (PEM) and post-exertional symptom exacerbation (PESE) on activities of daily living (ADLs). A validated questionnaire to measure self-reported ability with ADLs would advance research and...
  3. Hoopoe

    Is PEM a feature of sarcoidosis?

    This description in a paper on sarcoidosis sounds like PEM (although not much detail is given so it's not clear). In this study they also performed repeated CPET and found "no impairment of maximal exercise testing" on the second test...
  4. SunnyK

    PEM without heart rate change?

    I'm new to an ME diagnosis (got it Dec 27, 2022, although I'd had ME symptoms since 1994 if not before) but not new to cardiac issues. I've had lots of testing as a result of chest pain while exercising (nothing wrong with my heart; in retrospect an ME symptom related to pushing myself too hard)...
  5. Sly Saint

    Post-Exertional Malaise May Be Related to Central Blood Pressure, Sympathetic Activity and Mental Fatigue in CFS Patients, 2021, Kujawski et al

    Kujawski, Julia Newton et al Abstract Post-exertional malaise (PEM) is regarded as the hallmark symptom in chronic fatigue syndrome (CFS). The aim of the current study is to explore differences in CFS patients with and without PEM in indicators of aortic stiffness, autonomic nervous system...
  6. mango

    The Rest Room: What actually is Post-Exertional Malaise? with Todd Davenport

    Podcast episode about PEM, well worth a listen :thumbsup: https://natashalipman.substack.com/p/post-exertional-malaise Transcript here: http://natashalipman.com/post-exertional-malaise-podcast-transcript
  7. ahimsa

    ME/CFS and Post-Exertional Malaise among Patients with Long COVID, 2022, Jason et al

    ME/CFS and Post-Exertional Malaise among Patients with Long COVID by Leonard A. Jason and Joseph A. Dorri Abstract This study sought to ascertain the prevalence of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) among a sample of 465 patients with Long COVID. The participants...
  8. Andy

    Fatigue, post-exertional malaise and orthostatic intolerance: a map of Cochrane evidence relevant to rehabilitation for people with... 2022 Arienti

    Full title: Fatigue, post-exertional malaise and orthostatic intolerance: a map of Cochrane evidence relevant to rehabilitation for people with post COVID-19 condition INTRODUCTION: Rehabilitation focuses on impairments, activity limitations and participation restrictions being informed by the...
  9. Andy

    Effect of using a structured pacing protocol on post-exertional symptom exacerbation and health status in a longitudinal cohort... 2022 Parker et al

    Full title: Effect of using a structured pacing protocol on post-exertional symptom exacerbation and health status in a longitudinal cohort with the post-COVID-19 syndrome Background Post Exertional Symptom Exacerbation (PESE) is a characteristic symptom of Post-COVID Syndrome (PCS)...
  10. J

    OMF: Muscle Biopsy and Plasma Study into Post-Exertional Malaise, David Systrom, 2022

    From OMF news email Post Exertion Malaise (PEM): Dr. David Systrom Aims to Fill in Gaps Today we are pleased to highlight one of the studies included in our 2022 OMF supported research initiatives! Remember, when you give this November, your gift will be TRIPLED by generous donors. Hurry before...
  11. Sly Saint

    Unravelling the nature of postexertional malaise in ME/CFS: the role of elastase, complement C4a and interleukin-1β 2010, Nijs et al

    Unravelling the nature of postexertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome: the role of elastase, complement C4a and interleukin-1β Abstract Abstract. Nijs J, Van Oosterwijck J, Meeus M, Lambrecht L, Metzger K, Frémont M, Paul L (Vrije Universiteit Brussel...
  12. Sly Saint

    Insights from the Physiology of Post-Exertional Symptom Exacerbation by Dr. Todd Davenport

    About: Graded exercise is commonly prescribed after illness to improve symptoms and functional tolerance. Protracted and limited courses of recovery may be associated with post-exertional symptom exacerbation (PESE), which is common after many other forms of viral and bacterial infection...
  13. Lapis108

    Fatigue Scales in research

    Hi All, It's be really interested in what people's thoughts are for the most accurate fatigue scales that can be used in research studies? Ones that also give representation to PEM over time. The CFQ (chalder fatigue scale/ questionnaire) is often used but has serious limitations. The DePaul...
  14. Hoopoe

    ME/CFS might be caused by defects in cellular housekeeping

    This idea has come up before and I thought it would be interesting to write down some of my thoughts on this. Housekeeing processes have a role in keeping cells healthy by doing things such as maintaining structural integrity and degrading and recycling intracellular components (like...
  15. Mij

    Symptom variation, correlations, and relationship to physical activity in LC: intensive longitudinal study, 2022, Christopher Burton et al

    Abstract Background People with Long Covid (Post-Acute Sequelae of Covid-19) describe multiple symptoms which vary between and within individuals over relatively short time intervals. We aimed to describe the real-time associations between different symptoms and between symptoms and physical...
  16. Kalliope

    Plasma metabolomics reveals disrupted response and recovery following maximal exercise in ME/CFS, Arnaud Germain, Maureen R. Hanson et al, 2022

    JCI Insight Plasma metabolomics reveals disrupted response and recovery following maximal exercise in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Abstract Post-exertional malaise (PEM) is a hallmark symptom of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). We monitored...
  17. L

    Traumatic brain injury - similarities with and differences to ME/CFS, including PEM

    Thread split from UK NICE 2021 ME/CFS Guideline, published 29th October - post-publication discussion For those who want to share personal experiences on this topic less publicly there is a thread in the members only area here. ______________ I used to think it was unique. But I am starting...
  18. Arvo

    Coining a term for being limited in your interrelated energy and time.

    Just one of these things I have tumbling around in the back of my head for a while now, and I was curious about your opinion. One of the key characteristics of ME/CFS is that you are limited in what you can do, there is an "energy envelope" that is markedly smaller than pre-illness. You can...
  19. Dolphin

    "ME/CFS Crash Survival Guidebook: The Art of Living with ME/CFS" (Bateman Horne Center)

    Bateman Horne Center · RELEASED: "ME/CFS Crash Survival Guidebook: The Art of Living with ME/CFS" https://bit.ly/34nh5yX The guidebook is designed for the patient, their support network, and medical providers to: - Understand ME/CFS and its defining characteristic of post-exertional malaise...
  20. Kalliope

    JOSPT: Lessons from ME/CFS for Long COVID - 4 part series, 2022, Davenport et al

    Lessons from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome for Long COVID: Postexertional Symptom Exacerbations is an Abnormal Response to Exercise/Activity Authors: Todd E. Davenport, Staci R. Stevens, Jared Stevens, Christopher R. Snell, J. Mark Van Ness Quote: Prolonged symptoms after...
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