alzheimers

interesting story - he had NPH normal pressure hydrocephalus I’d not heard of that before but apparently it does get mistaken for Alzheimer’s https://www.bbc.co.uk/news/world-us-canada-49375308

https://www.washingtonpost.com/business/economy/pfizer-had-clues-its-blockbuster-drug-could-prevent-alzheimers-why-didnt-it-tell-the-world/2019/06/04/9092e08a-7a61-11e9-8bb7-0fc796cf2ec0_story.html?utm_term=.1418de0736c6 Not ME/CFS, but provides an overview of the difficulty of new drug...

https://www.cnn.com/2019/04/27/health/video-game-alzheimers-scn-trnd/index.html

Had this review pointed out to me as being potentially of interest. Open access at https://academic.oup.com/femsre/article/39/4/567/2467761

Might increased serum NfL also be a potential biomarker for ME/CFS since it is for Alzheimer’s and other neurological disorders? https://www.nature.com/articles/s41591-018-0304-3

Neuroinflammation findings with Alzheimer's, strikes a familiar note for pwME regarding our own neurological symptoms. A CBC radio program aired on Quirks and Quarks on December 8, 2018, discusses the theory of amyloid-beta plaques in Alzheimer's, protecting the brain from infection...

Artificial intelligence predicts Alzheimer's years before diagnosis in small UCSF study. Study: A Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using 18F-FDG PET of the Brain https://pubs.rsna.org/doi/10.1148/radiol.2018180958 Press Release: AI Predicts Alzheimers Years...

http://www.bbc.com/future/story/20181022-there-is-mounting-evidence-that-herpes-leads-to-alzheimers?ns_campaign=bbc_radio_4&ns_linkname=radio_and_music&ns_source=facebook&ns_mchannel=social

Scientific American article on the search for an Alzheimer's biomarker, and how both the FDA and Bill Gates have made finding an inexpensive blood test for Alzheimer's a priority. We Need New Biomarkers for Alzheimer's Disease They're essential to coming up with better treatments, and a new...

UDCA (Ursodeoxycholic Acid) is currently being used for Cholestasis and PBC. Posted here for its improval on Mitochondrial function. Link : https://www.sciencedirect.com/science/article/pii/S0022283618309872

Thought this was interesting, and that I could remember that lipids were of interest to us? https://www.alz.org/aaic/releases_2018/AAIC18-Tues-gut-liver-brain-axis.asp

https://www.alzheimersresearchuk.org/new-findings-link-activity-gut-liver-alzheimers-risk/ @mariovitali may be of interest

Abstract: Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging https://jamanetwork.com/journals/jamaneurology/article-abstract/2687472 Press release: Yale-developed test for Alzheimer’s disease directly measures synaptic...

Study: Five years before multiple sclerosis onset: Phenotyping the prodrome http://journals.sagepub.com/doi/full/10.1177/1352458518783662 Press Release: A constellation of symptoms presages first definitive signs of multiple sclerosis...

Preliminary work suggests that human herpesviruses 6A and 7 have key roles in Alzheimer disease https://www.jwatch.org/fw114301/2018/06/22/work-hints-herpesviruses-may-have-role-alzheimers Human herpesviruses 6A and 7 have occasionally been mentioned in connection with ME/CFS. Probably to get...

https://www.washingtonpost.com/news/national/wp/2018/06/13/feature/devastated-by-als-trying-to-save-others/?noredirect=on&utm_term=.65cc16c53602&wpisrc=nl_rainbow&wpmm=1

Alzheimer's drug development tends to focus on protein aggregates in the brain. And they've all failed. Alzheimer’s disease: why insulin is a new suspect https://theconversation.com/alzheimers-disease-why-insulin-is-a-new-suspect-97222

This may be of interest to some, The article, https://medicalxpress.com/news/2018-05-impaired-energy-production-brain-susceptible.amp The paper, https://www.cell.com/cell-reports/fulltext/S2211-1247(18)30703-4

https://www.forbes.com/sites/robinseatonjefferson/2018/04/27/report-offers-hope-outlines-537-new-drugs-in-development-for-neurological-disorders/

https://www.iospress.nl/ios_news/canadian-neuroscientists-say-daily-ibuprofen-can-prevent-alzheimers-disease/