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alzheimers

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  1. darrellpf
    Thread

    Mild cognitive impairment and donepezil impact mitochondrial respiratory capacity in skeletal muscle, 2021, Morris et al

    In conclusion, we show reduced mitochondrial respiration in skeletal muscle, a metabolic tissue that is critical for strength, movement, and...
    Thread by: darrellpf, Sep 28, 2021, 0 replies, in forum: Other Health News and Research
  2. Colin
    Thread

    Uncovering the prevalence and neural substrates of anhedonia in frontotemporal dementia (2021) Shaw et al

    Abstract Much of human behaviour is motivated by the drive to experience pleasure. The capacity to envisage pleasurable outcomes and to engage in...
    Thread by: Colin, Apr 20, 2021, 0 replies, in forum: Other Health News and Research
  3. mat
    Thread

    Public Attenuated CSF‐1R signalling drives cerebrovascular pathology

    Abstract Cerebrovascular pathologies occur in up to 80% of cases of Alzheimer's disease; however, the underlying mechanisms that lead to...
    Thread by: mat, Jan 5, 2021, 0 replies, in forum: Other Health News and Research
  4. Andy
    Thread

    Are infections seeding some cases of Alzheimer’s disease?

    But some recent research has provided intriguing hints that the two ideas could fit together — that infection could seed some cases of Alzheimer’s...
    Thread by: Andy, Nov 4, 2020, 1 replies, in forum: Other Health News and Research
  5. cassava7
    Thread

    A 3D human brain–like tissue model of herpes-induced Alzheimer’s disease, 2020, Cairns et al.

    Dana M. Cairns [1,2], Nicolas Rouleau [1,2], Rachael N. Parker [1], Katherine G. Walsh [3], Lee Gehrke [4] and David L. Kaplan [1,2]* 1....
    Thread by: cassava7, May 7, 2020, 0 replies, in forum: Other Health News and Research
  6. wigglethemouse
    Thread

    Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease (Jan2020) Gate, M.Davis & Wyss-Coray, Stanford)

    This paper on Alzheimer’s is interesting because Mark Davis (one of the authors) and team are using similar techniques on ME patients to look for...
    Thread by: wigglethemouse, Mar 26, 2020, 1 replies, in forum: Other Health News and Research
  7. rvallee
    Thread

    The maddening saga of how an Alzheimer’s ‘cabal’ thwarted progress toward a cure for decades

    Today, in ME headlines of the future: In more than two dozen interviews, scientists whose ideas fell outside the dogma recounted how, for decades,...
    Thread by: rvallee, Dec 9, 2019, 19 replies, in forum: Other Health News and Research
  8. Jaybee00
    Thread

    Alzheimer's Trial: Lessons From a Failed Drug — What the pragmatic trial of minocycline can teach us

    https://www.medpagetoday.com/neurology/alzheimersdisease/83410 mentions microglia inflammation. Cheap trial *only* cost $2 million.
    Thread by: Jaybee00, Nov 19, 2019, 11 replies, in forum: Other Health News and Research
  9. adambeyoncelowe
    Thread

    Do Alzheimer's and Lewy body disease have discrete pathological signatures of gait?

    Thought this was relevant since @Jonathan Edwards has mentioned gait as a possible diagnostic tool in ME. Objective We aimed to refine the...
    Thread by: adambeyoncelowe, Sep 22, 2019, 1 replies, in forum: Other Health News and Research
  10. Jaybee00
    Thread

    Pfizer had clues its blockbuster drug could prevent Alzheimer’s. Why didn’t it tell the world?

    https://www.washingtonpost.com/business/economy/pfizer-had-clues-its-blockbuster-drug-could-prevent-alzheimers-why-didnt-it-tell-the-world/2019/06/...
    Thread by: Jaybee00, Jun 5, 2019, 7 replies, in forum: Other Health News and Research
  11. Alvin
    Thread

    This video game can detect early stages of Alzheimer's better than medical tests, researchers say

    Just a few minutes of playing a certain video game could help identify the earliest stages of Alzheimer's in ways existing medical tests can't,...
    Thread by: Alvin, May 4, 2019, 4 replies, in forum: Other Health News and Research
  12. Andy
    Thread

    Review: The dormant blood microbiome in chronic, inflammatory diseases, 2015, Kell et al

    Had this review pointed out to me as being potentially of interest. Blood in healthy organisms is seen as a ‘sterile’ environment: it lacks...
    Thread by: Andy, Mar 7, 2019, 0 replies, in forum: Other Health News and Research
  13. leokitten
    Thread

    Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease (2019) Preische, et al.

    Might increased serum NfL also be a potential biomarker for ME/CFS since it is for Alzheimer’s and other neurological disorders?...
    Thread by: leokitten, Jan 22, 2019, 3 replies, in forum: Other Health News and Research
  14. DokaGirl
    Thread

    Neuroinflammtion theory for Alzheimer's strikes a familiar note for pwME

    Neuroinflammation findings with Alzheimer's, strikes a familiar note for pwME regarding our own neurological symptoms. A CBC radio program aired...
    Thread by: DokaGirl, Dec 9, 2018, 1 replies, in forum: Other Health News and Research
  15. Webdog
    Thread

    A Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using 18F-FDG PET of the Brain, 2018, Ding et al

    Artificial intelligence predicts Alzheimer's years before diagnosis in small UCSF study. Study: A Deep Learning Model to Predict a Diagnosis of...
    Thread by: Webdog, Nov 8, 2018, 1 replies, in forum: Other Health News and Research
  16. Cinders66
    Thread

    Alzheimer’s linked to herpes virus

    http://www.bbc.com/future/story/20181022-there-is-mounting-evidence-that-herpes-leads-to-alzheimers?ns_campaign=bbc_radio_4&ns_linkname=radio_and_m...
    Thread by: Cinders66, Oct 23, 2018, 0 replies, in forum: Other Health News and Research
  17. Webdog
    Thread

    Scientific American: "We Need New Biomarkers for Alzheimer's Disease"

    Scientific American article on the search for an Alzheimer's biomarker, and how both the FDA and Bill Gates have made finding an inexpensive blood...
    Thread by: Webdog, Sep 22, 2018, 0 replies, in forum: Other Health News and Research
  18. mariovitali
    Thread

    Ursodeoxycholic Acid Improves Mitochondrial Function and Redistributes Drp1 in Fibroblasts from Patients with Alzheimers disease, 2018,Mortiboys et al

    Ursodeoxycholic Acid Improves Mitochondrial Function and Redistributes Drp1 in Fibroblasts from Patients with either Sporadic or Familial...
    Thread by: mariovitali, Sep 3, 2018, 0 replies, in forum: Other Health News and Research
  19. Andy
    Thread

    Researchers Report New Data On How Gut Bacteria and Lipid Metabolism May Influence Alzheimer’s, Other Brain Diseases

    Thought this was interesting, and that I could remember that lipids were of interest to us? Four new studies reported at the Alzheimer’s...
    Thread by: Andy, Aug 5, 2018, 3 replies, in forum: Other Health News and Research
  20. NelliePledge
    Thread

    Alzheimer’s Research UK article about gut and liver

    https://www.alzheimersresearchuk.org/new-findings-link-activity-gut-liver-alzheimers-risk/ @mariovitali may be of interest
    Thread by: NelliePledge, Jul 29, 2018, 1 replies, in forum: Other Health News and Research
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