alzheimers

  1. John Mac

    BBC: Blood test shows if organs are ageing fast or slowly

    Similar to doing an MOT on a car, scientists believe they can run a blood test to check how fast a person's internal organs are ageing, and even predict which ones might soon fail. The Stanford University team say they can monitor 11 major body parts, including the heart, brain and lungs. They...
  2. rvallee

    Microbiota from Alzheimer’s patients induce deficits in cognition and hippocampal neurogenesis, 2023, Nolan et al

    Microbiota from Alzheimer’s patients induce deficits in cognition and hippocampal neurogenesis https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awad303/7308687 Brain, awad303, https://doi.org/10.1093/brain/awad303 Published: 18 October 2023 Abstract Alzheimer’s disease is a...
  3. E

    Severe acute respiratory syndrome coronavirus 2 infection leads to Tau pathological signature in neurons , 2023, Di Primo et al

    Severe acute respiratory syndrome coronavirus 2 infection leads to Tau pathological signature in neurons Abstract COVID-19 has represented an issue for global health since its outbreak in March 2020. It is now evident that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...
  4. SNT Gatchaman

    Review Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics, 2018, Petersen et al.

    Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics Petersen, Mark A.; Ryu, Jae Kyu; Akassoglou, Katerina The blood coagulation protein fibrinogen is deposited in the brain in a wide range of neurological diseases and traumatic injuries with blood–brain barrier (BBB)...
  5. Sly Saint

    Alzheimer's and Parkinson's could be halted by a protein that helps hedgehogs hibernate

    Alzheimer's and Parkinson's could be halted by a protein that helps hedgehogs hibernate (msn.com)
  6. Sly Saint

    Article Guardian: Could Alzheimer’s be caused by an infection?

    Could Alzheimer’s be caused by an infection? | Alzheimer's | The Guardian
  7. Sly Saint

    Professor Jernej Ule Delivers IoPPN Inaugural Lecture “Understanding protein-RNA condensates and their disruptions in ALS”

    The Centre Director for UK Dementia Research Institute at King’s was first to deliver a lecture as part of the 2022/23 IoPPN Inaugural Lecture Series. lecture (32 mins) available at link...
  8. SNT Gatchaman

    Recapitulation of pathophysiological features of AD [Alzheimer’s disease] in SARS-CoV-2 infected subjects, 2022/3, Griggs et al

    Preprint See post 5 for published version Molecular and cellular similarities in the brain of SARS-CoV-2 and Alzheimer’s disease individuals Elizabeth Griggs, Kyle Trageser, Sean Naughton, Eun-Jeong Yang, Brian Mathew, Grace Van Hyfte, Linh Hellmers, Nathalie Jette, Molly Estill, Li Shen, Tracy...
  9. Sly Saint

    Will Covid Brain Fog Increase Risks for Alzheimer’s Disease?

    https://www.psychologytoday.com/gb/blog/mental-mishaps/202209/will-covid-brain-fog-increase-risks-alzheimer-s-disease
  10. C

    Science, Blots on a field? (potential fabrication in Alzheimer's research), 2022, Charles Piller

    Article: Science, Blots on a field ?, Charles Piller First para: "In August 2021, Matthew Schrag, a neuroscientist and physician at Vanderbilt University, got a call that would plunge him into a maelstrom of possible scientific misconduct. A colleague wanted to connect him with an attorney...
  11. J

    Memory Enhancer Succeeds in Phase II Alzheimer's Trial

    https://www.medpagetoday.com/meetingcoverage/aan/98099
  12. Trish

    New insights into the genetic etiology of Alzheimer’s disease and related dementias, 2022, Bellenguez et al.

    New insights into the genetic etiology of Alzheimer’s disease and related dementias https://www.nature.com/articles/s41588-022-01024-z Abstract Characterization of the genetic landscape of Alzheimer’s disease (AD) and related dementias (ADD) provides a unique opportunity for a better...
  13. Mij

    An Association of Pathogens and Biofilms with Alzheimer’s Disease, 2021

    Abstract As one of the leading causes of dementia, Alzheimer’s disease (AD) is a condition in which individuals experience progressive cognitive decline. Although it is known that beta-amyloid (Aβ) deposits and neurofibrillary tangles (NFT) of tau fibrils are hallmark characteristics of AD, the...
  14. D

    Mild cognitive impairment and donepezil impact mitochondrial respiratory capacity in skeletal muscle, 2021, Morris et al

    In conclusion, we show reduced mitochondrial respiration in skeletal muscle, a metabolic tissue that is critical for strength, movement, and metabolism particularly in aging, during the earliest stages of AD-related cognitive decline; and effects that appear to be affected by the commonly used...
  15. J

    People Want an Alzheimer’s Drug. This Isn’t the One. NY Times

    https://www.nytimes.com/2021/05/28/opinion/alzheimer-treatment-FDA-aducanumab.html?action=click&module=Opinion&pgtype=Homepage They’ve spent billions on Alzheimer’s and sounds like they still have nothing. Worth reading even though it’s not about MECFS.
  16. Colin

    Uncovering the prevalence and neural substrates of anhedonia in frontotemporal dementia (2021) Shaw et al

    Abstract Much of human behaviour is motivated by the drive to experience pleasure. The capacity to envisage pleasurable outcomes and to engage in goal-directed behaviour to secure these outcomes depends upon the integrity of frontostriatal circuits in the brain. Anhedonia refers to the...
  17. J

    Lilly says Alzheimer's drug slows clinical decline in mid-stage trial

    https://www.reuters.com/article/us-elililly-alzheimers/lilly-says-alzheimers-drug-slows-clinical-decline-in-mid-stage-trial-idUSKBN29G161 https://www.bloomberg.com/news/articles/2021-01-11/lilly-surges-as-experimental-alzheimer-s-drug-shows-promise
  18. M

    Public Attenuated CSF‐1R signalling drives cerebrovascular pathology

    Abstract This is a significant finding not only on the Alzheimer's front. Previously, the exact role of the immune system in early-onset Alzheimer's was unclear. Early-onset Alzheimer's is one of the diseases also showing overlaps with CFS/ME. This is one of the reasons why a differential...
  19. Andy

    Are infections seeding some cases of Alzheimer’s disease?

    https://www.nature.com/articles/d41586-020-03084-9
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