A general thread on the PACE trial!

Just clicked on Richard Bentall's profile to see what he was saying, other than complaining about CFS researcher being so rudely treated, and it was him describing an MP an "amoral sociopath".



Then a few accusations of lying, eg:



Any double standards there?
 
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Bang up to date Cochrane review of trials (includes my own) that included exercise component (various control treatments). Compared to passive control (I guess you'd say this was the counterfactual) benefits for fatigue with no evidence of adverse effects:

Er, no. Bang up to date Cochrane review just of exercise was trashed and withdrawn. The one before that was also seen to be seriously deficient by the Cochrane editorial office and withdrawal was requested.

Dr Bengal sounds as if his next claim might be 'as long as we still have the British Empire things are fine'. And Illingworth is a jolly good batsman.
 
Blanchflower:
I agree that seems central - nobody said such a thing as far as I can see - plus there is evidence that exercise and therapy can help all sorts of conditions. Seems hard to think this is the odd one out.
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He really is out of his depth. If I could be bothered I might go on twitter and point out that 'bread is the staff of life' and there is evidence that bread is a nutritious healthy food, and it's hard to think that coeliac disease is the odd one out.
 
evidence that exercise and therapy can help all sorts of conditions

Probably the same worthless evidence?

Exercise is not a good idea for flu, aortic stenosis, haemophilia, osteogenesis imperfect, septicaemia, emphysema, tuberculosis, measles, aortic aneurysm, septic arthritis, ...
 
I'm sure I read somewhere that the NHS is sending the message through the ranks to stop recommending GET, but it will take 2 years to inform all doctors. Was this a dream/nightmare?

Can someone please point me to the place? Heartfelt thanks. Needed ASAP to challenge idiot Consultant.
 
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Squeezy said:
I'm sure I read somewhere that the NHS is sending the message through the ranks to stop recommending GET, but it will take 2 years to inform all doctors. Was this a dream/nightmare?

Can someone please point me to the place? Heartfelt thanks. Needed ASAP to challenge idiot Consultant.
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It was probably a dream. It wouldn't take 2 years. NICE could issue a treatment alert and stop it in an instant if they wanted to.
 
Squeezy said:
I'm sure I read somewhere that the NHS is sending the message through the ranks to stop recommending GET, but it will take 2 years to inform all doctors. Was this a dream/nightmare?

Can someone please point me to the place? Heartfelt thanks. Needed ASAP to challenge idiot Consultant.
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Are you maybe getting confused with the timeline for the new NICE guideline? Maybe someone heard about it and misinterpreted its implications perhaps?
 
@Lucibee Yep. If they wanted to. Crucial point. So no repeal of GET then? :cry:

@Barry it's bound to be me who's confused. Must look up the new NICE guidelines when not splatted with PEM. Thanks.
 
Can someone help me find some PACE- documents? I 'm looking for (1) the Q&A that used to be on the QMUL website and (2) the reanalysis the PACe authors published at the time the data was being released.

Many thanks in advance,
 
Michiel Tack said:
Can someone help me find some PACE- documents? I 'm looking for (1) the Q&A that used to be on the QMUL website and (2) the reanalysis the PACe authors published at the time the data was being released.

Many thanks in advance,
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The updated link is here: https://www.qmul.ac.uk/wolfson/research-projects/current-projects/projects/pace-trial.html

I'm not sure whether the original info is still all there though. I seem to recall someone (maybe @Tom Kindlon ?) posted an updated link to the PACE trial authors' own reanalysis according to the original protocol (for improvement) a few months (weeks?) ago... but I can't now find it.

ETA: Aha! Here it is: THE PACE TRIAL: ANALYSIS OF PRIMARY OUTCOMES USING COMPOSITE MEASURES OF IMPROVEMENT https://www.qmul.ac.uk/wolfson/medi...col_based_analysis_final_8th_Sept_2016(1).pdf

it was filed under "News"
 
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