What does MS fatigue feel like?
(Aug 2, 2019) by Jennifer Huizen - Medical News Today
I don't believe ME/CFS and MS are experiencing fatigue the same way, but I think it is interesting that MS, known to be a neurological disease, can have a profound type of fatigue they believe stems from the...
Full title: Multiple Sclerosis: Melatonin, Orexin, and Ceramide Interact with Platelet Activation Coagulation Factors and Gut-Microbiome-Derived Butyrate in the Circadian Dysregulation of Mitochondria in Glia and Immune Cells
Open access, https://www.mdpi.com/1422-0067/20/21/5500/htm
From MS society Facebook
“It’s finally here! Today we’re launching our most ambitious appeal ever. You’ll see people with MS on TV and in print, shouting loudly that we’re ready to stop MS. We’re aiming to raise £100 million. Leading researchers believe that we could have treatments that work...
A short literature review of the neuroanatomical correlates of fatigue in MS:
https://journals.sagepub.com/doi/abs/10.1177/1352458519876032?journalCode=msja
So the big European MS meeting just finished a couple of days ago. The scientific program book is 131 pages long for a three day meeting!!
https://www.professionalabstracts.com/ectrims2019/programme-ectrims2019.pdf
Why is there so much more MS research than MECFS research? Are there really...
Lipid profile is associated with decreased fatigue in individuals with progressive multiple sclerosis following a diet-based intervention: Results from a pilot study
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218075
Popular article...
Download the MSQLI: A User’s Manual (PDF)
https://www.nationalmssociety.org/For-Professionals/Researchers/Resources-for-Researchers/Clinical-Study-Measures/Modified-Fatigue-Impact-Scale-(MFIS)
Fatigue Impact Scale (Fisk et al, 1994b)...
I'm not a medical doctor so I don't know whether suggestions like this are common for other illnesses. It seems plausible to me on a superficial level that possibly people with ME/CFS should avoid vaccinations during relapses. Like many things, it would be great to have more research done on...
https://multiplesclerosisnewstoday.com/news-posts/2019/08/26/persistent-ms-related-fatigue-linked-to-damage-in-specific-brain-regions/
Study here
https://journals.sagepub.com/doi/10.1177/1352458519869185
https://www.theguardian.com/society/2019/aug/08/watchdog-declines-to-back-nhs-cannabis-treatment-for-epilepsy
There seem to be some worrying parallels with Nice’s review of guidelines for ME. If only clinical trials are considered as evidence, where do we stand? Also if the guidelines committee...
Not a new article, but I was struck by this comment on the relation between fatigue and pro-inflammatory cytokines:
link to the article here
There are are no consistently observed associations between fatigue in ME and levels of pro-inflammatory cytokines. But its interesting to see we're not...
Interesting bit if research via Twitter tonight.
Relevant to ME ?
https://www.pasteur.fr/en/research-journal/news/discovery-mechanism-responsible-chronic-inflammation-patients-suffering-multiple-sclerosis?hootPostID=81f61df8a3de6b440bfd9a65a34a12ef
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