multiple sclerosis

  1. Patient4Life

    What does MS fatigue feel like? (Aug 2, 2019) by Jennifer Huizen - Medical News Today

    What does MS fatigue feel like? (Aug 2, 2019) by Jennifer Huizen - Medical News Today I don't believe ME/CFS and MS are experiencing fatigue the same way, but I think it is interesting that MS, known to be a neurological disease, can have a profound type of fatigue they believe stems from the...
  2. Andy

    Increased Serological Response Against Human Herpesvirus 6A Is Associated With Risk for Multiple Sclerosis, 2019, Engdahl et al

    Open access, https://www.frontiersin.org/articles/10.3389/fimmu.2019.02715/full Press release, https://eurekalert.org/pub_releases/2019-11/ki-mlt112519.php
  3. John Mac

    A logistic regression analysis of risk factors in ME/CFS pathogenesis. Lacerda et al. 2019

    https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-019-1468-2
  4. Andy

    MS: Melatonin, Orexin, and Ceramide Interact with Platelet Activation Coagulation Factors and Gut-Microbiome-Derived Butyrate.., 2019, Anderson et al

    Full title: Multiple Sclerosis: Melatonin, Orexin, and Ceramide Interact with Platelet Activation Coagulation Factors and Gut-Microbiome-Derived Butyrate in the Circadian Dysregulation of Mitochondria in Glia and Immune Cells Open access, https://www.mdpi.com/1422-0067/20/21/5500/htm
  5. C

    UK: MS society launch major £100m fundraising drive

    From MS society Facebook “It’s finally here! Today we’re launching our most ambitious appeal ever. You’ll see people with MS on TV and in print, shouting loudly that we’re ready to stop MS. We’re aiming to raise £100 million. Leading researchers believe that we could have treatments that work...
  6. D

    Brain anatomical correlates of fatigue in multiple sclerosis (2019) (Palotai & Guttmann)

    A short literature review of the neuroanatomical correlates of fatigue in MS: https://journals.sagepub.com/doi/abs/10.1177/1352458519876032?journalCode=msja
  7. Sly Saint

    The role of infections in multiple sclerosis - Marrodan,Alessandro,Farez,Correale Jun 2019

    https://www.ncbi.nlm.nih.gov/pubmed/30638421 https://sci-hub.tw/10.1177/1352458518823940
  8. J

    MS research versus ME/CFS research

    So the big European MS meeting just finished a couple of days ago. The scientific program book is 131 pages long for a three day meeting!! https://www.professionalabstracts.com/ectrims2019/programme-ectrims2019.pdf Why is there so much more MS research than MECFS research? Are there really...
  9. Sly Saint

    Biomarkers of intestinal barrier function in multiple sclerosis are associated with disease activity. 2019, Camarra-Lemaroy,Silva,Greenfield,Liu et al

    https://www.ncbi.nlm.nih.gov/pubmed/31317818 scihub https://sci-hub.tw/10.1177/1352458519863133
  10. J

    Lipid profile is associated with decreased fatigue in individuals with progressive multiple sclerosis following a diet-based intervention: Results fro

    Lipid profile is associated with decreased fatigue in individuals with progressive multiple sclerosis following a diet-based intervention: Results from a pilot study https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218075 Popular article...
  11. Sly Saint

    Measuring fatigue in Multiple Sclerosis - The Modified Fatigue Impact Scale

    Download the MSQLI: A User’s Manual (PDF) https://www.nationalmssociety.org/For-Professionals/Researchers/Resources-for-Researchers/Clinical-Study-Measures/Modified-Fatigue-Impact-Scale-(MFIS) Fatigue Impact Scale (Fisk et al, 1994b)...
  12. J

    Effect of dalfampridine on information processing speed impairment in multiple sclerosis, 2019

    https://n.neurology.org/content/93/8/e733 Popular article Old MS Drug May Improve Cognitive Function https://www.medscape.com/viewarticle/916495
  13. Dolphin

    "For patients having a Multiple Sclerosis relapse, vaccination should be delayed until the relapse is no longer active"

    I'm not a medical doctor so I don't know whether suggestions like this are common for other illnesses. It seems plausible to me on a superficial level that possibly people with ME/CFS should avoid vaccinations during relapses. Like many things, it would be great to have more research done on...
  14. J

    Microstructural fronto-striatal and temporo-insular alterations are associated with fatigue in patients with multiple sclerosis 2019 Palotai et al

    https://multiplesclerosisnewstoday.com/news-posts/2019/08/26/persistent-ms-related-fatigue-linked-to-damage-in-specific-brain-regions/ Study here https://journals.sagepub.com/doi/10.1177/1352458519869185
  15. C

    MS society funds study of immune system to understand why pregnancy can alleviate autoimmune conditions, possible ME relevances

    https://www.mssociety.org.uk/research/latest-research/latest-research-news-and-blogs/could-we-harness-the-power-of-pregnancy-to-stop-ms?
  16. Binkie4

    Public Nice guidelines and Cannabis treatment for epilepsy and MS

    https://www.theguardian.com/society/2019/aug/08/watchdog-declines-to-back-nhs-cannabis-treatment-for-epilepsy There seem to be some worrying parallels with Nice’s review of guidelines for ME. If only clinical trials are considered as evidence, where do we stand? Also if the guidelines committee...
  17. wastwater

    T cell-selective deletion of Oct1 protects animals from autoimmune neuroinflammation while maintaining neurotropic pathogen response (2019) Tantin

    https://multiplesclerosisnewstoday.com/news-posts/2019/07/03/study-in-mice-suggests-possible-treatment-approach-for-multiple-sclerosis-in-humans/
  18. Woolie

    Multiple sclerosis-associated fatigue. Krupp et al. (2010)

    Not a new article, but I was struck by this comment on the relation between fatigue and pro-inflammatory cytokines: link to the article here There are are no consistently observed associations between fatigue in ME and levels of pro-inflammatory cytokines. But its interesting to see we're not...
  19. J

    The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003444/ Fig. 5 looks pretty good. Anybody try this?
  20. A

    MS - ancient viral DNA and inflammatory immune response

    Interesting bit if research via Twitter tonight. Relevant to ME ? https://www.pasteur.fr/en/research-journal/news/discovery-mechanism-responsible-chronic-inflammation-patients-suffering-multiple-sclerosis?hootPostID=81f61df8a3de6b440bfd9a65a34a12ef
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