It needs to be stated again that medicine really doesn't understand fatigue, nor know how to treat it.
The drugs: amantadine, modafinil, methylphenidate. Not surprised about the last 2 not being effective, never heard of the first. Just like pain, the entire field of fatigue research needs a complete reset. You can't progress without a basic understanding of what it is, starting with a damn common and clear vocabulary. Literally start over from scratch with a fresh batch of people, there's nothing of value to be found in there yet. Case in point: Fatigue is not sleepiness. Just. Stop. You are very bad at this. Wait, no, I meant : Actually what I meant is: Have you literally never checked the scientific literature on this topic? Seriously?
Stimulants are pretty effective for things like narcolepsy, etc., so there are some treatments available for certain conditions.
I think it was Dr. Paul Cheney who rx'd Amantadine (antiviral) usually used to treat Type-A influenza virus and is sometimes used in ME/CFS for its stimulating properties.
Yes, I keep thinking of that quoted tweet of Dr Amy Small (I think IIRC) Having long-covid symptoms she acknowledged that as a dr she had no idea what people meant when talking about post viral fatigue. Fatigue seemed inadequate. I'm restating this but I believe this was the gist. Doctors inevitably think that people who come in with chronic symptoms of pain and / or fatigue are equivalent to what they have experienced in their lives if they ever had these symptoms in some acute illness or physical trauma.
It was used to treat herpesvirus and cocaine addiction so it was embarrassing to collect from the chemist I was given it in 1985 but it did not help my fatigue. It may have influenced my results that I had a 9 month old baby who slept for 2 hours a day.