me/cfs

Abstract Background and Objective: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a severe illness with the hallmark symptom of Post-Exertional Malaise (PEM). Currently, no biomarkers or established diagnostic tests for ME/CFS exist. In Germany, it is estimated that over 300,000...

Preprint Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic and debilitating disease that is characterized by unexplained physical fatigue unrelieved by rest. Symptoms also include cognitive and sensory dysfunction, sleeping disturbances, orthostatic intolerance...

https://meassociation.org.uk/2021/06/guest-blog-the-shame/

Migraine is a symptomatically heterogeneous condition, of which headache is just one manifestation. Migraine is a disorder of altered sensory thresholding, with hypersensitivity among sufferers to sensory input. Advances in functional neuroimaging have highlighted that several brain areas are...

Abstract In healthcare settings, patient participation is increasingly adopted as a possible remedy to ill people suffering from ‘epistemic injustices’ – that is to their unfair harming as knowers. In exploring and interpreting patient participation discourses within the 2013–2018 Dutch Myalgic...

Nature - molecular psychiatry Chronic post-COVID-19 syndrome and chronic fatigue syndrome: Is there a role for extracorporeal apheresis? - Bornstein et al Abstract As millions of patients have been infected by SARS-CoV-2 virus a vast number of individuals complain about continuing...

The Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients with Joint Hypermobility Show Larger Cerebral Blood Flow Reductions during Orthostatic Stress Testing Than Patients without Hypermobility: A Case Control Study Linda M.C. van Campen Stichting CardioZorg, Planetenweg 5, 2132 HN...

Abstract Objective: There is limited research examining the impact of the validity of cognitive test performance on treatment outcome. All known studies to date have operationalized performance validity dichotomously, leading to the loss of predictive information. Using the range of scores on a...

Note:this article is provisionally accepted Abstract: The evidence of an association between Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and chronic herpesviruses infections remains inconclusive. Two possible reasons for this lack of consistent evidence are the large...

Abstract Objective: How can it be that a disease as serious as CFS affecting such a large number of people could be so unknown to the general population? The answer given to this question is based on Pierre Bourdieu’s analyzes of symbolic violence. Method: The “letters to the editor” by CFS...

Video: Fatigue, Pacing and PEM Management | Lessons from ME/CFS - With Dr Ben Marsh I know this video has been mentioned on another thread but I think it might have been missed by many and deserves a thread of its own. In Episode 3 of our expert interviews series, Dr Asad Khan talks to Dr Ben...

There are some issues and concerns around the IDO2 tryptophan trap hypothesis about ME. These are my current thought directions, and should not be considered scientific fact. Please comment, add links, agree or disagree, or move this post to somewhere better if you are a moderator. Concerns...

Split from Effect of Galantamine Hydrobromide in Chronic Fatigue Syndrome A Randomized Controlled Trial, 2004, Blacker et al.. The quote in this post refers to the Blacker paper. This might also be of interest. It's the main result of an open-label study by Vermeulen et al. published in 2004...

(Note that this is an old study from 2004) Abstract Context: There is no established pharmacological treatment for the core symptoms of chronic fatigue syndrome (CFS). Galantamine hydrobromide, an acetyl cholesterone inhibitor, has pharmacological properties that might benefit patients with...

Funded study in progress. Abstract: Background: Paediatric Chronic Fatigue Syndrome or Myalgic Encaphalistis (CFS/ME) is disabling and relatively common (1-2% of teenagers). We need to improve treatment but need a well developed Patient Reported Outcome Measure (PROM) to do this. Clinical...

Abstract The Wessely School’s (WS) approach to medically unexplained symptoms, myalgic encephalomyelitis and chronic fatigue syndrome (MUS/MECFS) is critically reviewed using scientific criteria. Based on the ‘Biopsychosocial Model’, the WS proposes that patients’ dysfunctional beliefs...

A person-centred test of multidimensional perfectionism and health in people with chronic fatigue syndrome versus healthy controls Fuschia M. Sirois, Loren Toussaint, Jameson K. Hirsch, Niko Kohls, Martin Offenbacher Abstract: Theory and evidence suggests that person-centred models may be...

Abstract Background: Chronic fatigue syndrome (CFS) is a complex disease with few effective and safe therapies. Young Yum Pill (YYP), a proprietary herbal drug, has been used to relieve CFS-like symptoms. The pharmacological basis of this application of YYP is unknown. Purpose: This study...

Preprint Abstract A proportion of patients surviving acute COVID-19 infection develop post-COVID syndrome (long COVID) encompassing physical and neuropsychiatric symptoms lasting longer than 12 weeks. Here we studied a prospective cohort of individuals with long COVID (the ADAPT study) compared...

Trends in Molecular Medicine Insights from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome May Help Unravel the Pathogenesis of Post-Acute COVID-19 Syndrome Anthony L. Komaroff, W. Ian Lipkin Highlights • In some people, the aftermath of acute COVID-19 is a lingering illness with fatigue...