Moved from Six-month sequelae of post-vaccination SARS-CoV-2 infection: a retrospective cohort study of 10,024 breakthrough infections, 2021, Taquet et al @Hutan thank you, I believe it's all coming together and Long Covid will have been instrumental. The Pretorius micro-clot finding is key: Ron Davis found "something in the blood" that was reasonably large (< cell size, but > molecule). He found abnormal impedance in the blood of ME/CFS patients Filtering plasma by size removed most of the abnormal impedance effect Transferring ME plasma to normal (mice) causes ME/fibromyalgia type symptomatology Resia Pretorius found serum amyloid (SAA4) - 17.5 x control level in the microclots Amyloid is formed of abnormal beta-pleated sheets and causes abnormal impedance Amyloid tends to induce further protein misfolding The implications are massive: ME and long COVID are the same disease, both an amyloid pathology that affects the blood and causes coagulation, immune and inflammatory derangement centred at the micro-circulation level. Downstream symptoms are all secondary (haemodynamic, neuroinflammation, gut wall permeability). There is an element of the virus that kicks this amyloid formation process off (and I think we can guess what element that is).