long covid

Plasma from patients with pulmonary embolism show aggregates that reduce after anticoagulation Baker, Stephen R.; Halliday, Georgia; Ząbczyk, Michal; Alkarithi, Ghadir; Macrae, Fraser L.; Undas, Anetta; Hunt, Beverley J.; Ariëns, Robert A. S. Background Microclots, a term also used for amyloid...

Prolonged indoleamine 2,3-dioxygenase-2 activity and associated cellular stress in post-acute sequelae of SARS-CoV-2 infection Background Post-acute sequela of SARS-CoV-2 infection (PASC) encompass fatigue, post-exertional malaise and cognitive problems. The abundant expression of the...

Uncertainties about the Roles of Anticoagulation and Microclots in Post-acute Sequelae of SARS-CoV-2 Infection Jean M. Connors; Robert A.S. Ariëns Three years after the start of the pandemic, approaches to the prevention and treatment of acute Covid-19 have been established. However, post-acute...

Long COVID: Alice Evans, brucellosis, and reflections on infectious causes of chronic disease Smith, Tara C Despite over a century of research on the link between infection and chronic diseases, we again find ourselves flummoxed by a new pathogen that causes long-term impairment. Patients have...

Long-Term Dysfunction of Taste Papillae in SARS-CoV-2 BACKGROUND We sought to determine whether ongoing taste disturbance in the postacute sequelae of coronavirus disease 2019 period is associated with persistent virus in primary taste tissue. METHODS We performed fungiform papillae biopsies...

Plasmapheresis to remove amyloid fibrin(ogen) particles for treating the post‐COVID‐19 condition Background The post‐COVID‐19 condition (PCC) consists of a wide array of symptoms including fatigue and impaired daily living. People seek a wide variety of approaches to help them recover. A...

Associations between symptoms and functional capacity in patients after COVID-19 infection and community controls Quan Huynh; Noah Wexler; Joel Smith; Leah Wright; Felicia Ho; Richard Allwood; Yusuke Sata; Stefano Manca; Erin Howden; Thomas H. Marwick Background: Post-acute sequelae of COVID-19...

Abstract The COVID-19 pandemic caused by the coronavirus 2 of the severe acute respiratory syndrome (SARS-CoV-2) has significantly affected people around the world, leading to substantial morbidity and mortality. Although the pandemic has affected people of all ages, there is increasing...

Abstract Purpose Postural sway and physical capacity had not previously been compared between people with long COVID and people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Therefore, this study determined postural sway and physical capacity in people with long COVID (∼16...

Cortical thickness alterations and systemic inflammation define long-COVID patients with cognitive impairment Abstract As the heterogeneity of symptoms is increasingly recognized among long-COVID patients, it appears highly relevant to study potential pathophysiological differences along the...

Association between duration of SARS-CoV-2 positivity and long COVID Pozzi, Chiara; Sarti, Riccardo; Levi, Riccardo; Mollura, Maximiliano; Azzolini, Elena; Barbieri, Riccardo; Mantovani, Alberto; Rescigno, Maria In an observational study, we analyzed 1,293 healthcare workers previously infected...

A Systematic Review of Persistent Clinical Features After SARS-CoV-2 in the Pediatric Population https://publications.aap.org/pediatrics/article/doi/10.1542/peds.2022-060351/192816/A-Systematic-Review-of-Persistent-Clinical AAP Pediatrics OBJECTIVE: To present the prevalence and...

"The value of clinical cardiopulmonary exercise testing (CPET) within healthcare settings has been established in the last decade. CPET methods remain highly relevant in the COVID-19 endemic phase and should be used to assess those recovering from COVID-19 infection. This diagnostic tool could...

Full title: The effects of COVID-19 on cognitive performance in a community-based cohort: a COVID symptom study biobank prospective cohort study Summary Background Cognitive impairment has been reported after many types of infection, including SARS-CoV-2. Whether deficits following SARS-CoV-2...

Myopathy as a cause of Long COVID fatigue: Evidence from quantitative and single fiber EMG and muscle histopathology Highlights Myopathic changes in qEMG and/or increased jitter in sfEMG were seen in 63% of 84 patients with Long COVID neuromuscularsymptoms. Low quality of life score correlated...

Abstract Background Long COVID is a debilitating chronic condition that has affected over 100 million people globally. It is characterized by a diverse array of symptoms, including fatigue, cognitive dysfunction and respiratory problems. Studies have so far largely failed to identify genetic...

Spotted this today on Twitter. It's the professor and psychologist Gerd Kvale sharing her opinions about Long Covid. Gerd Kvale has developed a fast version of CBT for anxiety and OCD, with good results in clinical trials. She has also published a paper with psychiatrist Bjarte Stubhaug (who...

Link to published version here Preprint Abstract To understand the roles of acute phase viral dynamics and host immune responses in PASC, we enrolled 136 participants within 5 days of their first positive SARS-CoV-2 real-time PCR. Participants self-collected nasal specimens up to 21 times...

Hippocampal subfield abnormalities and biomarkers of pathologic brain changes: from SARS-CoV-2 acute infection to post-COVID syndrome Maria Díez-Cirarda; Miguel Yus-Fuertes; Rafael Sanchez-Sanchez; Javier J. Gonzalez-Rosa; Gabriel Gonzalez-Escamilla; Lidia Gil-Martínez; Cristina Delgado-Alonso...

Vagus nerve inflammation contributes to dysautonomia in COVID-19 Woo, Marcel S.; Shafiq, Mohsin; Fitzek, Antonia; Dottermusch, Matthias; Altmeppen, Hermann; Mohammadi, Behnam; Mayer, Christina; Bal, Lukas C.; Raich, Lukas; Matschke, Jakob; Krasemann, Susanne; Pfefferle, Susanne; Brehm, Thomas...