long covid

Abstract A significant proportion of patients after SARS-CoV-2 infection suffer from long-lasting symptoms. Although many different symptoms are described, the majority of patients complains about neuropsychological symptoms. Additionally, a subgroup of patients fulfills diagnostic criteria for...

The kynurenine pathway relates to post-acute COVID-19 objective cognitive impairment and PASC Abstract Objective To determine the prevalence and natural history of post-acute COVID-19 objective cognitive impairment and function, and their relationship to demographic, clinical factors...

A thread for news from the US that isn't covered by other threads such as (in no particular order) USA: News from the Workwell Foundation. USA: News from Solve ME USA: NIH National Institutes of Health Overview of NIH grants for ME/CFS research USA: News from #MEAction USA: The RECOVER...

Functional characterisation of the ACE2 orthologues in Drosophila provides insights into the neuromuscular complications of COVID-19 Highlights A large percentage of patients with COVID-19 have neuromuscular manifestations. Loss of Drosophila ACE2 orthologues Ance or Ance3 impaired motoric...

Long COVID-19 Cardiac Complications Are Associated With Autoimmunity to Cardiac Self-Antigens Sufficient to Cause Cardiac Dysfunction No access to the paper... https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.062672 A post by Eric Topol .

Exercise in long COVID is poorly studied. Nevertheless, exerciserehabilitation could improve cardiorespiratory, muscular and autonomic functions. We aimed to investigate improvement in physical and autonomic performances of long COVID patients (n = 38) after a 4-week exercise rehabilitation...

Long COVID and Significant Activity Limitation Among Adults, by Age — United States, June 1–13, 2022, to June 7–19, 2023 Nicole D. Ford et al. Long COVID is a condition encompassing a wide range of health problems that emerge, persist, or return following COVID-19. CDC analyzed national repeat...

Ivabradine effects on COVID-19-associated postural orthostatic tachycardia syndrome: a single center prospective study Background: A wide range of cardiac arrhythmias were reported in the setting of active infection or as a complication of COVID-19. The main pathophysiology can be attributed...

Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts Joseph W. Guarnieri; Joseph M. Dybas; Hossein Fazelinia; Man S. Kim; Justin Frere; Yuanchao Zhang; Yentli Soto Albrecht; Deborah G. Murdock; Alessia Angelin; Larry N. Singh; Scott L. Weiss; Sonja M...

Attenuation of ferroptosis as a potential therapeutic target for neuropsychiatric manifestations of post-COVID syndrome Sousa, Ricardo A. L.; Yehia, Asmaa; Abulseoud, Osama A. Coronavirus disease-19 (COVID-19), caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), is...

Long COVID in a highly vaccinated population infected during a SARS-CoV-2 Omicron wave - Australia, 2022 Mulu Woldegiorgis; Gemma Cadby; Sera Ngeh; Rosemary Korda; Paul Armstrong; Jelena Maticevic; Paul Knight; Andrew Jardine; Lauren Bloomfield; Paul Effler Objective: To characterise Long COVID...

Forming a consensus opinion to inform long COVID support mechanisms and interventions: a modified Delphi approach Background Current approaches to support patients living with post-COVID condition, also known as Long COVID, are highly disparate with limited success in managing or resolving a...

Full title: Digital home monitoring for capturing daily fluctuation of symptoms; a longitudinal repeated measures study: Long Covid Multi-disciplinary Consortium to Optimise Treatments and Services across the NHS (a LOCOMOTION study) Abstract Introduction A substantial proportion of COVID-19...

Review of Hyperpolarized Pulmonary Functional 129Xe MR for Long-COVID Jim M. Wild; Fergus V. Gleeson; Sarah Svenningsen; James T. Grist; Laura C. Saunders; Guilhem J. Collier; Maksym Sharma; Sam Tcherner; Ali Mozaffaripour; Alexander M. Matheson; Grace Parraga The respiratory consequences of...

Clinical And Serological Predictors Of Post Covid-19 Condition: Findings From A Canadian Prospective Cohort Study Erin Collins; Yannick Galipeau; Corey Arnold; Anne Bhéreur; Ronald Booth; C Arianne Buchan; Curtis Cooper; Angela M Crawley; Pauline Mccluskie; Michaeline McGuinty; Martin Pelchat...

Differential effects of SARS-CoV-2 variants on central nervous system cells and blood–brain barrier functions Background Although mainly causing a respiratory syndrome, numerous neurological symptoms have been identified following of SARS-CoV-2 infection. However, how the virus affects the...

Prevalence of long-term symptoms varies by using different post-COVID-19 definitions in positively and negatively tested adults: the PRIME post-COVID study Abstract Background Long-term symptoms after a SARS-CoV-2 infection (i.e., post-COVID-19 condition or long COVID), constitute a substantial...

VEGF-A plasma levels are associated with impaired DLCO and radiological sequelae in long COVID patients Background Long COVID, also known as post-acute sequelae of COVID-19 (PASC), is characterized by persistent clinical symptoms following COVID-19. Objective To correlate biomarkers of...

Persistent immune and clotting dysfunction detected in saliva and blood plasma after COVID-19 Hyesun Jang; Saibyasachi Choudhury; Yanbao Yu; Benjamin L. Sievers; Terri Gelbart; Harinder Singh; Stephen A. Rawlings; Amy Proal; Gene S. Tan; Yu Qian; Davey Smith; Marcelo Freire A growing number of...

Now published - link here ****** Preprint Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to Two Years Following COVID-19 Michael J Peluso; Dylan M Ryder; Robert Flavell; Yingbing Wang; Jelena Levi; Brian H LaFranchi; Tyler-Marie M Deveau...