Thought this was an interesting editorial. It's from 2004 but is still relevant.
Source: http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC351829&blobtype=pdf
Evelien and I were interested in what clinical trials are currently planned or ongoing for ME/CFS. It can take many years to conduct a clinical trial and report the results, so we wanted to know what we can expect to come out in the next years.
A search of databases that register clinical...
Full title: Effects of the prolong life with nine turn method (Yan Nian Jiu Zhuan) Qigong on patients with chronic fatigue syndrome: study protocol for a randomized controlled trial
Open access PDF available from http://apm.amegroups.com/article/view/48615
Full title: Recruiting Adolescents With Chronic Fatigue Syndrome/Myalgic Encephalomyelitis to Internet-Delivered Therapy: Internal Pilot Within a Randomized Controlled Trial
Open access, https://www.jmir.org/2020/8/e17768/
Very troubling study by prof Knoop et al.
"ONDERZOEKSVRAAG
To investigate whether delivering timely Cognitive Behavioural Therapy [CBT], an evidence-based treatment for chronic fatigue, is effective in preventing the development of post-COVID-19 chronic fatigue.
URGENTIE
A substantial...
Effectiveness of Psychological Interventions to Improve Quality of Life in People With Long-Term Conditions: Rapid Systematic Review of Randomised Controlled Trials
Niall Anderson 1 2 , Gozde Ozakinci 3
https://pubmed.ncbi.nlm.nih.gov/29587884/
eta: posted this study as is basis of...
CODEs study group
ProfLaura HGoldsteinPhDaEmily JRobinsonMScbgJohn D CMellersMRCPsychhProfJonStonePhDiProfAlanCarsonMDiProfMarkusReuberPhDjNickMedfordPhDhProfPaulMcCronePhDcJoannaMurrayBAdProfMark...
The feasibility and acceptability of an early intervention in primary care to prevent chronic fatigue syndrome (CFS) in adults: randomised controlled trial
https://pilotfeasibilitystudies.biomedcentral.com/articles/10.1186/s40814-020-00595-0
From their May Momentum 2020 newsletter & https://www.omf.ngo/maymomentum/
Post-COVID19 study: https://www.omf.ngo/2020/04/26/tracking-covid-19-patients/
Mestinon trial: https://www.omf.ngo/2020/04/26/the-mestinon-clinical-trial-for-me-cfs/ &...
via Dr. Marc-Alexander Fluks
Source: University of Bristol Date: November 28, 2019 URL: https://research-information.bris.ac.uk/en/theses/a-qualitative-exploration-of-treatment-preference-in-paediatric-randomised-controlled-trials(e6ff1d3b-e315-45e2-a4da-18ae0b414a1d).html...
Pre-print, https://www.biorxiv.org/content/10.1101/2020.02.20.958249v1
April 2023 - now published, see here
Achieving symptom relief in patients with ME by targeting the neuro-immune interface and inducing disease tolerance (2020) Rodriguez et al
ETA: Added word, "Pre-print".
https://www.sciencedirect.com/science/article/abs/pii/S0033318214001935?via%3Dihub
https://doi.org/10.1016/j.psym.2014.12.003
Lesley Arnold, Thomas Blom, Jeffrey Welge, Elizabeth Mariutto, Alicia Heller
Women’s Health Research Program, Department of Psychiatry and Behavioral Neuroscience...
Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)
full paper
https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-019-02196-9
Psychosomatic therapy for patients frequently attending primary care with medically unexplained symptoms, the CORPUS trial: study protocol for a randomised controlled trial
Open access, published Dec 2019
Trial status
The protocol version number and date: version 10, 8 May 2018. Patient...
Activity registration in ME/CFS
Would you like to be part of developing new methods for future clinical trials?
We are seeking participants for a study to test the activity device Fitbit Charge 3 for measurement of physical activity in patients with ME/CFS.
The study doesn't entail any...
Full title: The Efficacy and Safety of Myelophil, an Ethanol Extract Mixture of Astragali Radix and Salviae Radix, for Chronic Fatigue Syndrome: A Randomized Clinical Trial
Open access, https://www.frontiersin.org/articles/10.3389/fphar.2019.00991/full
I'm dubious about the value of this paper...
I know that fatigue≠ME/CFS but maybe the study might be of some use, possibly (I doubt it but you never know).
Paywall, https://www.sciencedirect.com/science/article/abs/pii/S0965229919301542
Sci hub, https://sci-hub.se/10.1016/j.ctim.2019.05.027
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