Compelling evidence from meta-epidemiological studies demonstrates overestimation of effects in randomized trials that fail to optimize...
Many High-Quality Randomized Controlled Trials in Sports Physical Therapy Are Making False-Positive Claims of Treatment Effect: A Systematic...
Objective Our aim was to conduct a pilot randomized controlled trial of a novel cognitive behaviorally based intervention for pediatric PNES...
Background Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a severely debilitating disease of unknown pathogenesis consisting of a...
We have previously discussed interventions that manipulate how patients report symptoms as a separate form of bias, rather than as part of the...
Hopin Lee, PhD1,2; Aidan G. Cashin, PhD3,4; Sarah E. Lamb, DPhil1,5; Sally Hopewell, DPhil1; Stijn Vansteelandt, PhD6,7; Tyler J. VanderWeele,...
A major new consortium involving the University of Exeter, has been awarded £6.8 million by the National Institute of Health Research (NIHR) to...
First Clinical Study of the Safety and Blood Levels of a Human Monoclonal Antibody (2217LS) Against Lyme Disease Bacteria in Healthy People, 2021,...
Given the rise in ACT 'research' this might be useful/of interest: Last updated: March 2021 The following information will be provided about...
The methodological quality of 176,620 randomized controlled trials published between 1966 and 2018 reveals a positive trend but also an urgent...
Cognitive Behavioral Therapy Improves Physical Function and Fatigue in Mild and Moderate Chronic Fatigue Syndrome: A Consecutive Randomized...
Preprint Effect of Melatonin Plus Zinc Supplementation on Fatigue Perception in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized,...
Background Despite evidence of selective outcome reporting across multiple disciplines, this has not yet been assessed in trials studying the...
When is lack of scientific integrity a reason for retracting a paper? A case study. Abstract: Objective: The present and past editors of this...
Background Postural orthostatic tachycardia syndrome (POTS) is a complex, multifaceted disorder that impairs functional status and quality of...
An SSRI to treat early COVID, supposedly SSRIs can inhibit SARS-CoV-2 and also potentially have anti-inflammatory and immunoregulatory properties....
Thought it could be helpful to have a thread on Jonathan's expert testimony for any further use and citation. Edwards, Jonathan CW (2020), The...
ABSTRACT Background: There is a disconnect between the ability to swiftly develop e-therapies for the treatment of depression, anxiety, and...
Thought this was an interesting editorial. It's from 2004 but is still relevant. The history of medicine is replete with examples of treatments...
Evelien and I were interested in what clinical trials are currently planned or ongoing for ME/CFS. It can take many years to conduct a clinical...
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