pots

Background: Orthostatic intolerance (OI) is a core finding in individuals with myalgic encephalomyelitis /chronic fatigue syndrome (ME/CFS). Deconditioning is often proposed as an important determinant for OI. Deconditioning can be objectively classified using the predicted peak oxygen...

Introduction: In patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) a higher-than-normal resting heart rate has been reported in a number of studies. As heart rate is linked to stroke volume, the present study explored the relationship between the supine heart rate and...

Detection of G Protein-Coupled Receptor Autoantibodies in Postural Orthostatic Tachycardia Syndrome Using Standard Methodology (the title is a bit misleading, read the whole abstract) Main author is Dr Satish Raj from Calgary. Abstract Background: Postural orthostatic tachycardia syndrome...

Abstract Background: Orthostatic tachycardia (OT) affects some patients after concussion/mild traumatic brain injury (mTBI). In this study, we sought to identify the factors associated with increased risk for OT in patients with mTBI. Methods: We conducted a retrospective review of 268...

Objectives: Pediatric acute-onset neuropsychiatric syndrome (PANS) is characterized by an abrupt-onset of severe psychiatric symptoms including OCD, anxiety, cognitive difficulties, and sleep issues which is thought to be a post-infection brain inflammatory disorder. We observed postural...

Abstract Purpose Postural orthostatic tachycardia syndrome (POTS) is a debilitating and poorly understood disorder of the autonomic nervous system with many different causes, mostly seen in females of child-bearing age. This study used an illness representation framework to explore the lived...

Merged thread I wasn't sure where to post this. I haven't watched it, so I have no idea what it's like.

Salt from the autonomic perspective, 2022, William P Cheshire - editorial https://www.sciencedirect.com/science/article/pii/S1566070222000297?dgcid=author#bb0005

Abstract Background: Postural tachycardia syndrome (POTS) is characterized by excessive upright tachycardia and disabling presyncopal symptoms, which are exacerbated after consuming a high-carbohydrate meal; it is unknown, however, what is the precise underlying mechanism. We seek to...

Platelet Storage Pool Deficiency and Elevated Inflammatory Biomarkers Are Prevalent in Postural Orthostatic Tachycardia Syndrome by William T. Gunning, Paula M. Kramer, Jacob A. Cichock, Beverly L. Karabin, Sadik A. Khuder, Blair P. Grubb doi.org/10.3390/cells11050774...

https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-022-03289-8 Benjamin H. Natelson Jin-Mann S. Lin Michelle Blate Sarah Khan Yang Chen Elizabeth R. Unger Open access Background Orthostatic intolerance-OI is common in Myalgic Encephalomyelitis/Chronic Fatigue...

Abstract Purpose Previous studies demonstrated M2 muscarinic acetylcholine receptor-activating autoantibodies (M2R-AAb) were present in some patients with postural tachycardia syndrome (POTS). This study examines how these autoantibodies might contribute to the pathophysiology of POTS, and...

Abstract In normal subjects natriuresis is tightly coupled to dietary salt ingestion to maintain sodium balance. Likewise, blood pressure remains unchanged over a wide range of salt intake because of pressure natriuresis, whereby an increase in blood pressure stimulates renal sodium excretion...

Gluten-free diet in postural orthostatic tachycardia syndrome (POTS), 2022, Zha et al Abstract Objectives Postural orthostatic tachycardia syndrome (POTS) is a chronic disorder of the autonomic nervous system that is associated with orthostatic intolerance (OI) and gastrointestinal (GI)...

This came into my mailbox. i thought i’d share. Full text here . Interestingly the authors are affiliated to King’s College in London. Abstract Background: There have been previous reports of enhanced sympathoexcitation in autism spectrum disorder (ASD). However, there has been no formal...

The postural tachycardia syndrome, or PoTS, was named and defined in 1993,1 but is likely synonymous with earlier conditions such as ‘The Soldier’s Heart’, a term coined by Sir James Mackenzie in 1916.2 Affected patients experience an abnormal response to upright posture resulting in multiple...

Characterization and Intervention Studies in Patients with Postural Orthostatic Tachycardia Syndrome and Inappropriate Sinus Tachycardia Associated with Post-Acute COVID-19 Syndrome Principal Investigator: Dr. Marcus Stahlberg [Ståhlberg], Karolinska University, Sweden "The overall purpose of...

Orthostatic Symptoms and Reductions in Cerebral Blood Flow in Long-Haul COVID-19 Patients: Similarities with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Abstract Background and Objectives: Symptoms and hemodynamic findings during orthostatic stress have been reported in both long-haul...

Highlights Long COVID symptoms include fatigue, brain fog, anosmia, dysgeusia, orthostatic intolerance Long COVId symptoms overlap with those of chronic fatigue syndrome (ME/CFS) and POTS. Reduced cerebral blood flow is a feature of dysautonomia in ME/CFS and POTS. Stellate ganglion block...

Abstract As part of the non-criteria clinical manifestations, postural orthostatic tachycardia syndrome (POTS), a multisystem autonomic dysfunction, can co-exist with antiphospholipid syndrome (APS). Several pieces of evidence hint on the autoimmune basis of POTS, and its possible association...