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Characterization and Intervention Studies in Patients with POTS and IST Associated with PACS (planned study) Ståhlberg et al

Discussion in 'Long Covid research' started by mango, Dec 26, 2021.

  1. mango

    mango Senior Member (Voting Rights)

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    Characterization and Intervention Studies in Patients with Postural Orthostatic Tachycardia Syndrome and Inappropriate Sinus Tachycardia Associated with Post-Acute COVID-19 Syndrome

    Principal Investigator: Dr. Marcus Stahlberg [Ståhlberg], Karolinska University, Sweden

    "The overall purpose of this project is two-fold. First, the researchers aim to describe the biological mechanisms and identify potential novel therapeurtic targets in Long COVID patients with cardiovascular autonomic dysfunction (postural orthostatic tachycardia syndrome, inappropriate sinus tachycardia, tachycardia not meeting the POTS or IST criteria) and microvascular endothelial dysfunction.

    Long COVID patients from clinics around Sweden will be screened using tilt table and other autonomic testing, mast cell activation syndrome biomarkers, lipidomics, proteomics (mass spectrometry), stress-perfusion cardiac MRI, assessment of endothelial function, 6 minute walk test, quality of life and other self-reported screenings from the time of Long COVID diagnosis until four years after diagnosis.

    The second stage of the study includes randomized placebo controlled, double-blinded clinical trials assessing the efficacy of various interventions, including ivabradine, naltrexone, fulvic acid and enhanced external counter pulsation (EECP).

    The goal is to deliver rapid evidence-based treatments and to discover novel therapeutic targets that can benefit other Long COVID, POTS and IST patients."

    https://dysautonomiainternational.salsalabs.org/2021researchgrants/index.html
     
  2. mango

    mango Senior Member (Voting Rights)

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  3. alktipping

    alktipping Senior Member (Voting Rights)

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    enhanced external counter pulsation (EECP). there is not at present sufficient evidence for this to be excepted by mainstream cardiologists , seems like quackery to me have a treatment designed now lets find a use for it . this is only my opinion based on years of seeing such things mentioned in print and of course the numerous discussion on suspect papers on sfme .
     
  4. Milo

    Milo Senior Member (Voting Rights)

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    What is it? Never heard of it. A search on the forum yields no results other than this thread.

    Did you mean accepted?

    Will take your word. So thankful we are S4ME and that we can smell quackery from far.
     
  5. mango

    mango Senior Member (Voting Rights)

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