platelets

  1. SNT Gatchaman

    Dysregulated Platelet Function in Patients with Post-Acute Sequelae of COVID-19, 2023, Aggarwal et al.

    Link to post with the abstract of the final published paper here Preprint Dysregulated Platelet Function in Patients with Post-Acute Sequelae of COVID-19 Anu Aggarwal; Tamanna K. Singh; Michael Pham; Matthew Godwin; Rui Chen; Thomas M. McIntyre; Alliefair Scalise; Mina K. Chung; Courtney...
  2. SNT Gatchaman

    A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk, 2023, Verdier et al.

    A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk Verdier, Hippolyte; Thomas, Patrick; Batista, Joana; Kempster, Carly; McKinney, Harriet; Gleadall, Nicholas; Danesh, John; Mumford, Andrew; Heemskerk, Johan W. M.; Ouwehand, Willem H...
  3. SNT Gatchaman

    Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis, 2023, Wang et al.

    Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis Jue Wang; Shiva Keshava; Kaushik Das; Richard Kolesnick; Xian-Cheng Jiang; Usha R. Pendurthi; L. Vijaya Mohan Rao BACKGROUND: Our recent studies suggest that sphingomyelin levels in the plasma membrane influence TF (tissue...
  4. SNT Gatchaman

    Characterization of Unique Pathological Features of COVID-Associated Coagulopathy: Studies with AC70 hACE2 Transgenic Mice, 2023, Drelich et al.

    Now published - details here ********** Preprint Characterization of Unique Pathological Features of COVID-Associated Coagulopathy: Studies with AC70 hACE2 Transgenic Mice Highly Permissive to SARS-CoV-2 Infection Aleksandra K Drelich; Kempaiah Rayavara; Jason Hsu; Panatda Saenkham-Huntsinger...
    • SNT Gatchaman
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    • annexin anxa2 coagulopathy covid 19 fibrinolysis long covid mice neutrophil extracellular traps platelets
    • Replies: 3
    • Forum: Long Covid research
  5. SNT Gatchaman

    Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID, 2023, Wang et al

    Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID Kaiming Wang; Mobin Khoramjoo; Karthik Srinivasan; Paul M.K. Gordon; Rupasri Mandal; Dana Jackson; Wendy Sligl; Maria B. Grant; Josef M. Penninger; Christoph H. Borchers; David S. Wishart...
    • SNT Gatchaman
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    • arginine long covid metabolic methionine multi-omics platelets serotonin t cells taurine
    • Replies: 4
    • Forum: Long Covid research
  6. SNT Gatchaman

    Prolonged platelet hyperactivity after COVID-19 infection, 2023, Nara et al.

    Prolonged platelet hyperactivity after COVID-19 infection Noriko Nara; Mie Shimizu; Masahiro Yamamoto; Tomoki Nakamizo; Azusa Hayakawa; Ken Johkura Platelet hyperactivity often occurs in patients with coronavirus disease 2019 (COVID-19). However, it remains unclear how long platelet...
  7. SNT Gatchaman

    COVID-19 promotes endothelial dysfunction and thrombogenicity: Role of pro-inflammatory cytokines/SGLT2 pro-oxidant pathway, 2023, Mroueh et al.

    COVID-19 promotes endothelial dysfunction and thrombogenicity: Role of pro-inflammatory cytokines/SGLT2 pro-oxidant pathway Ali Mroueh; Walaa Fakih; Adrien Carmona; Antonin Trimaille; Kensuke Matsushita; Benjamin Marchandot; Abdul Wahid Qureshi; Dal-Seong Gong; Cyril Auger; Laurent Sattler...
    • SNT Gatchaman
    • Thread
    • coagulation covid-19 cytokines endothelial dysfunction enos il-1b il-6 nf-κb nitric oxide oxidative stress platelets redox tnf
    • Replies: 0
    • Forum: Long Covid research
  8. E

    Digital holo-tomographic 3D maps of COVID-19 microclots in blood to assess disease severity, 2023, Bergaglio

    Digital holo-tomographic 3D maps of COVID-19 microclots in blood to assess disease severity Abstract The coronavirus disease 2019 (COVID-19) has impacted health globally. Cumulative evidence points to long-term effects of COVID-19 such as cardiovascular and cognitive disorders diagnosed in...
    • EndME
    • Thread
    • dhtm holotomographic microscopy hyperactivated platelets microclots platelets raman spectroscopy
    • Replies: 7
    • Forum: Long Covid research
  9. SNT Gatchaman

    Hemostatic abnormalities in patients with Ehlers–Danlos syndrome, 2018, Artoni et al.

    Hemostatic abnormalities in patients with Ehlers–Danlos syndrome A. Artoni; A. Bassotti; M. Abbattista; B. Marinelli; A. Lecchi; F. Gianniello; M. Clerici; P. Bucciarelli; S. La Marca; F. Peyvandi; I. Martinelli Background: Ehlers–Danlos syndrome (EDS) includes a heterogeneous group of...
  10. SNT Gatchaman

    Characterization of bleeding symptoms in Ehlers–Danlos syndrome, 2023, Kumskova et al.

    Characterization of bleeding symptoms in Ehlers–Danlos syndrome Mariia Kumskova; Gagan D. Flora; Janice Staber; Steven R. Lentz; Anil K. Chauhan Background Easy bruising is included as a major or minor criterion for the classification of multiple types of Ehlers–Danlos syndrome (EDS). Despite a...
  11. SNT Gatchaman

    Review Blood Coagulation and Beyond: Position Paper from the Fourth Maastricht Consensus Conference on Thrombosis, 2023, Akbulut et al.

    Blood Coagulation and Beyond: Position Paper from the Fourth Maastricht Consensus Conference on Thrombosis Asim Cengiz Akbulut; Ryanne A. Arisz; Constance C. F. M. J. Baaten; Gaukhar Baidildinova; Aarazo Barakzie; Rupert Bauersachs; Jur ten Berg; Wout W. A. van den Broek; H. C. de Boer; Amandine...
  12. Andy

    Dysregulation of extracellular vesicle protein cargo in female ME/CFS cases & sedentary controls in response to maximal exercise, 2023 Giloteaux et al

    Preprint. Now published - see post #18 This is from Maureen Hanson's group. Abstract In healthy individuals, physical exercise improves cardiovascular health and muscle strength, alleviates fatigue, and reduces risk of chronic diseases. Although exercise is suggested as a lifestyle...
    • Andy
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    • clusterin coagulation exercise challenge extracellular vesicles fibronectin germain giloteaux grp78 maureen hanson me/cfs platelets
    • Replies: 20
    • Forum: ME/CFS research
  13. SNT Gatchaman

    Platelet factors attenuate inflammation and rescue cognition in ageing, 2023, Schroer et al.

    Platelet factors attenuate inflammation and rescue cognition in ageing Schroer, Adam B.; Ventura, Patrick B.; Sucharov, Juliana; Misra, Rhea; Chui, M. K. Kirsten; Bieri, Gregor; Horowitz, Alana M.; Smith, Lucas K.; Encabo, Katriel; Tenggara, Imelda; Couthouis, Julien; Gross, Joshua D.; Chan...
  14. SNT Gatchaman

    Monitoring circulating platelet activity to predict cancer-associated thrombosis, 2023, Li et al.

    Monitoring circulating platelet activity to predict cancer-associated thrombosis Li; Lu; Yang; Zhang; Wang; Chu; Wang; Qi; Anderson; Jiang; Song; Nie; Li A characteristic clinical complication in cancer patients is the frequent incidence of thrombotic events. Numerous studies have shown...
  15. SNT Gatchaman

    Coronary “Microvascular Dysfunction”: Evolving Understanding of Pathophysiology, Clinical Implications, and Potential Therapeutics, 2023, Kei et al.

    Coronary “Microvascular Dysfunction”: Evolving Understanding of Pathophysiology, Clinical Implications, and Potential Therapeutics Kei, Chun Yeung; Singh, Kuljit; Dautov, Rustem F.; Nguyen, Thanh H.; Chirkov, Yuliy Y.; Horowitz, John D. Until recently, it has been generally held that stable...
  16. SNT Gatchaman

    Are the integrin binding motifs within SARS CoV-2 spike protein and MHC class II alleles playing the key role in COVID-19?, 2023, Gerencer & McGuffin

    Are the integrin binding motifs within SARS CoV-2 spike protein and MHC class II alleles playing the key role in COVID-19? Gerencer, Marijan; McGuffin, Liam J. The previous studies on the RGD motif (aa403-405) within the SARS CoV-2 spike (S) protein receptor binding domain (RBD) suggest that...
  17. Mij

    Dissecting Platelet’s Role in Viral Infection: A Double-Edged Effector of the Immune System, 2023, Hajar El Filaly

    Abstract Platelets play a major role in the processes of primary hemostasis and pathological inflammation-induced thrombosis. In the mid-2000s, several studies expanded the role of these particular cells, placing them in the “immune continuum” and thus changing the understanding of their...
  18. SNT Gatchaman

    Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature by monocytes in COVID-19, 2022, Maher et al

    Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature by monocytes in COVID-19 Maher, Allison K; Burnham, Katie L; Jones, Emma M; Tan, Michelle MH; Saputil, Rocel C; Baillon, Laury; Selck, Claudia; Giang, Nicolas; Argüello, Rafael; Pillay, Clio; Thorley, Emma...
  19. SNT Gatchaman

    Trial Report Outpatient treatment of Covid-19 and the development of Long Covid..., 2023, Bramante et al

    Edit: Paper now published Post with abstract here. Outpatient Treatment of COVID-19 and the Development of Long COVID Over 10 Months: A Multi-Center, Quadruple-Blind, Parallel Group Randomized Phase 3 Trial Link (Open access to full paper) ************** Preprint abstract Outpatient...
  20. LarsSG

    Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC)..., 2022, Kell & Pretorius et al

    Abstract Background Post-acute sequelae of COVID-19 (PASC), also now known as long COVID, has become a major global health and economic burden. Previously, we provided evidence that there is a significant insoluble fibrin amyloid microclot load in the circulation of individuals with long COVID...
    • LarsSG
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    • fibrin kallikreins kell long covid microclots pf4 platelets pretorius
    • Replies: 1
    • Forum: Long Covid research
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