platelets

  1. SNT Gatchaman

    Opinion Long COVID-19 and Peripheral Serotonin: A Commentary and Reconsideration, 2024, Anderson et al.

    Long COVID-19 and Peripheral Serotonin: A Commentary and Reconsideration George M Anderson; Edwin H Cook; Randy D Blakely; James S Sutcliffe; Jeremy Veenstra-VanderWeele We believe there are serious problems with a recently published and highly publicized paper entitled “Serotonin reduction in...
  2. SNT Gatchaman

    Plasma Instead of Serum Avoids Critical Confounding of Clinical Metabolomics Studies by Platelets, 2024, Hagn et al.

    Plasma Instead of Serum Avoids Critical Confounding of Clinical Metabolomics Studies by Platelets Gerhard Hagn; Samuel M. Meier-Menches; Günter Plessl-Walder; Gaurav Mitra; Thomas Mohr; Karin Preindl; Andreas Schlatter; Doreen Schmidl; Christopher Gerner; Gerhard Garhöfer; Andrea Bileck...
  3. SNT Gatchaman

    Amyloid-Fibrinogen Aggregates Microclots Predict Risks of Disseminated Intravascular Coagulation and Mortality, 2024, Schofield et al.

    Amyloid-Fibrinogen Aggregates Microclots Predict Risks of Disseminated Intravascular Coagulation and Mortality Schofield, Jeremy; Abrams, Simon Timothy; Jenkins, Rosalind; Lane, Steven; Wang, Guozheng; Toh, Cheng-Hock Microclots have been associated with various conditions, including post-acute...
  4. SNT Gatchaman

    Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment, 2024, Greene et al

    Preprint Blood-brain barrier disruption in Long COVID-associated cognitive impairment Chris Greene, Ruairi Connolly, Declan Brennan, Aoife Laffan, Eoin O'Keeffe, Lilia Zaporojan, Emma Connolly, Cliona Ni Cheallaigh, Niall Conlon, Colin Doherty, Matthew Campbell Vascular disruption has been...
    • SNT Gatchaman
    • Thread
    • blood brain barrier brain imaging coagulation csf dce-mri endothelial gfap icam-1 inflammation long covid long covid clinic mri p-selectin pf4 platelets s100 scam-1 spike protein t cells tgf-beta tnf
    • Replies: 44
    • Forum: Long Covid research
  5. SNT Gatchaman

    AC-73 and Syrosingopine Inhibit SARS-CoV-2 Entry into Megakaryocytes by Targeting CD147 and MCT4, 2024, Spinello et al.

    AC-73 and Syrosingopine Inhibit SARS-CoV-2 Entry into Megakaryocytes by Targeting CD147 and MCT4 Spinello, Isabella; Saulle, Ernestina; Quaranta, Maria Teresa; Pelosi, Elvira; Castelli, Germana; Cerio, Annamaria; Pasquini, Luca; Morsilli, Ornella; Dupuis, Maria Luisa; Labbaye, Catherine...
  6. rvallee

    Persistent complement dysregulation with signs of thromboinflammation in active Long Covid, 2024, Boyman et al

    Persistent complement dysregulation with signs of thromboinflammation in active Long Covid Open access: https://www.science.org/doi/10.1126/science.adg7942 Editor’s summary Some individuals can endure persistent, debilitating symptoms for many months after an initial severe acute respiratory...
    • rvallee
    • Thread
    • cd41 complement complement system long covid lysis platelet hyperactivity platelets red blood cells thromboinflammation
    • Replies: 23
    • Forum: Long Covid research
  7. LarsSG

    Blood transcriptomics reveal persistent SARS-CoV-2 RNA and candidate biomarkers in Long COVID patients, 2024, Menezes et al.

    Published as a preprint. See post #7 And now published in final form - link here ****** This is an abstract from the Demystifying Long COVID International Conference 2023, converted from an image on Twitter, so it might be slightly wonky, but it looks intriguing. Blood Transcriptomics Reveal...
    • LarsSG
    • Thread
    • biomarker ets1 fyn pi3k platelets transcriptomics viral persistence
    • Replies: 19
    • Forum: Long Covid research
  8. Mij

    Single-cell RNA-Seq reveals intracellular microbial diversity within immune cells during SARS-CoV-2 infection and recovery, 2023, Sunita Yadav et al

    Highlights 76 bacterial species of 15 genera across healthy, COVID-19-positive, and recovered individuals Higher abundance of opportunistic intracellular bacteria in recovered group Higher microbial abundance within antigen-presenting cells of COVID-19 patients Differential microbial abundance...
    • Mij
    • Thread
    • b cells covid dendritic cells innate immune response intracellular infection intracellular pathogen macrophages monocytes nk cells pbmc plasma cells platelets single-cell transcriptomics t cells
    • Replies: 6
    • Forum: Epidemics (including Covid-19, not Long Covid)
  9. SNT Gatchaman

    Dysregulated Platelet Function in Patients with Post-Acute Sequelae of COVID-19, 2023, Aggarwal et al.

    Link to post with the abstract of the final published paper here Preprint Dysregulated Platelet Function in Patients with Post-Acute Sequelae of COVID-19 Anu Aggarwal; Tamanna K. Singh; Michael Pham; Matthew Godwin; Rui Chen; Thomas M. McIntyre; Alliefair Scalise; Mina K. Chung; Courtney...
  10. SNT Gatchaman

    A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk, 2023, Verdier et al.

    A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk Verdier, Hippolyte; Thomas, Patrick; Batista, Joana; Kempster, Carly; McKinney, Harriet; Gleadall, Nicholas; Danesh, John; Mumford, Andrew; Heemskerk, Johan W. M.; Ouwehand, Willem H...
  11. SNT Gatchaman

    Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis, 2023, Wang et al.

    Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis Jue Wang; Shiva Keshava; Kaushik Das; Richard Kolesnick; Xian-Cheng Jiang; Usha R. Pendurthi; L. Vijaya Mohan Rao BACKGROUND: Our recent studies suggest that sphingomyelin levels in the plasma membrane influence TF (tissue...
  12. SNT Gatchaman

    Characterization of Unique Pathological Features of COVID-Associated Coagulopathy: Studies with AC70 hACE2 Transgenic Mice, 2023, Drelich et al.

    Now published - details here ********** Preprint Characterization of Unique Pathological Features of COVID-Associated Coagulopathy: Studies with AC70 hACE2 Transgenic Mice Highly Permissive to SARS-CoV-2 Infection Aleksandra K Drelich; Kempaiah Rayavara; Jason Hsu; Panatda Saenkham-Huntsinger...
    • SNT Gatchaman
    • Thread
    • annexin anxa2 coagulopathy covid 19 fibrinolysis long covid mice neutrophil extracellular traps neutrophils platelets
    • Replies: 3
    • Forum: Long Covid research
  13. SNT Gatchaman

    Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID, 2023, Wang et al

    Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID Kaiming Wang; Mobin Khoramjoo; Karthik Srinivasan; Paul M.K. Gordon; Rupasri Mandal; Dana Jackson; Wendy Sligl; Maria B. Grant; Josef M. Penninger; Christoph H. Borchers; David S. Wishart...
    • SNT Gatchaman
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    • arginine long covid metabolic methionine multi-omics platelets serotonin t cells taurine
    • Replies: 4
    • Forum: Long Covid research
  14. SNT Gatchaman

    Prolonged platelet hyperactivity after COVID-19 infection, 2023, Nara et al.

    Prolonged platelet hyperactivity after COVID-19 infection Noriko Nara; Mie Shimizu; Masahiro Yamamoto; Tomoki Nakamizo; Azusa Hayakawa; Ken Johkura Platelet hyperactivity often occurs in patients with coronavirus disease 2019 (COVID-19). However, it remains unclear how long platelet...
  15. SNT Gatchaman

    COVID-19 promotes endothelial dysfunction and thrombogenicity: Role of pro-inflammatory cytokines/SGLT2 pro-oxidant pathway, 2023, Mroueh et al.

    COVID-19 promotes endothelial dysfunction and thrombogenicity: Role of pro-inflammatory cytokines/SGLT2 pro-oxidant pathway Ali Mroueh; Walaa Fakih; Adrien Carmona; Antonin Trimaille; Kensuke Matsushita; Benjamin Marchandot; Abdul Wahid Qureshi; Dal-Seong Gong; Cyril Auger; Laurent Sattler...
    • SNT Gatchaman
    • Thread
    • coagulation covid-19 cytokines endothelial dysfunction enos il-1b il-6 nf-κb nitric oxide oxidative stress platelets redox tnf
    • Replies: 0
    • Forum: Long Covid research
  16. E

    Digital holo-tomographic 3D maps of COVID-19 microclots in blood to assess disease severity, 2023, Bergaglio

    Digital holo-tomographic 3D maps of COVID-19 microclots in blood to assess disease severity Abstract The coronavirus disease 2019 (COVID-19) has impacted health globally. Cumulative evidence points to long-term effects of COVID-19 such as cardiovascular and cognitive disorders diagnosed in...
    • EndME
    • Thread
    • dhtm holotomographic microscopy hyperactivated platelets microclots platelets raman spectroscopy
    • Replies: 7
    • Forum: Long Covid research
  17. SNT Gatchaman

    Hemostatic abnormalities in patients with Ehlers–Danlos syndrome, 2018, Artoni et al.

    Hemostatic abnormalities in patients with Ehlers–Danlos syndrome A. Artoni; A. Bassotti; M. Abbattista; B. Marinelli; A. Lecchi; F. Gianniello; M. Clerici; P. Bucciarelli; S. La Marca; F. Peyvandi; I. Martinelli Background: Ehlers–Danlos syndrome (EDS) includes a heterogeneous group of...
  18. SNT Gatchaman

    Characterization of bleeding symptoms in Ehlers–Danlos syndrome, 2023, Kumskova et al.

    Characterization of bleeding symptoms in Ehlers–Danlos syndrome Mariia Kumskova; Gagan D. Flora; Janice Staber; Steven R. Lentz; Anil K. Chauhan Background Easy bruising is included as a major or minor criterion for the classification of multiple types of Ehlers–Danlos syndrome (EDS). Despite a...
  19. SNT Gatchaman

    Review Blood Coagulation and Beyond: Position Paper from the Fourth Maastricht Consensus Conference on Thrombosis, 2023, Akbulut et al.

    Blood Coagulation and Beyond: Position Paper from the Fourth Maastricht Consensus Conference on Thrombosis Asim Cengiz Akbulut; Ryanne A. Arisz; Constance C. F. M. J. Baaten; Gaukhar Baidildinova; Aarazo Barakzie; Rupert Bauersachs; Jur ten Berg; Wout W. A. van den Broek; H. C. de Boer; Amandine...
  20. Andy

    Dysregulation of extracellular vesicle protein cargo in female ME/CFS cases & sedentary controls in response to maximal exercise, 2023 Giloteaux et al

    Preprint. Now published - see post #18 This is from Maureen Hanson's group. Abstract In healthy individuals, physical exercise improves cardiovascular health and muscle strength, alleviates fatigue, and reduces risk of chronic diseases. Although exercise is suggested as a lifestyle...
    • Andy
    • Thread
    • clusterin coagulation ephrin exercise challenge extracellular vesicles fibronectin germain giloteaux grp78 maureen hanson me/cfs platelets thrombospondin-1
    • Replies: 20
    • Forum: ME/CFS research
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