platelets

  1. LarsSG

    Prevalence of symptoms, comorbidities, fibrin amyloid microclots and platelet pathology in individuals with Long COVID..., 2022, Pretorius, Kell et al

    Abstract Background Fibrin(ogen) amyloid microclots and platelet hyperactivation previously reported as a novel finding in South African patients with the coronavirus 2019 disease (COVID-19) and Long COVID/Post-Acute Sequelae of COVID-19 (PASC), might form a suitable set of foci for the clinical...
    • LarsSG
    • Thread
    • amyloid fibrin long covid microclots platelets pretorius symptoms
    • Replies: 1
    • Forum: Long Covid research
  2. Andy

    Sustained VWF-ADAMTS13 axis imbalance and endotheliopathy in Long COVID syndrome is related to immune dysfunction, 2022, Fogarty et al

    Abstract Background Prolonged recovery is common after SARs-CoV-2 infection, however the pathophysiological mechanisms underpinning Long COVID syndrome remain unknown. VWF-ADAMTS13 imbalance, dysregulated angiogenesis and immuno-thrombosis are hallmarks of acute COVID-19. We hypothesized that...
    • Andy
    • Thread
    • adamts13 endothelial immune dysfunction pf4 platelets vwf
    • Replies: 2
    • Forum: Long Covid research
  3. SNT Gatchaman

    Premortem skin biopsy assessing microthrombi, IFN I antiviral & regulatory proteins and complement correlates with Covid19 clinical stage, 2022

    Premortem Skin Biopsy Assessing Microthrombi, Interferon I Antiviral and Regulatory Proteins, and Complement Deposition Correlates with Coronavirus Disease 2019 Clinical Stage Jeffrey Laurence, Gerard Nuovo, Sabrina E. Racine-Brzostek, Madhav Seshadri, Sonia Elhadad, A. Neil Crowson, J. Justin...
  4. Andy

    ...Relation Between [FM] Severity and Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and Mean Platelet Volume, 2022, Jayakrishnan et al

    Abstract Background: Fibromyalgia is characterized by chronic widespread pain, which has been linked to neuroinflammation. Hematological indices, i.e., neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) have been shown to be effective...
  5. Hutan

    Is chronic fatigue syndrome associated with platelet activation?, 2006, Kennedy et al

    Note - from 2006 https://pubmed.ncbi.nlm.nih.gov/16479189/ Abstract Chronic fatigue syndrome (CFS) is a debilitating condition that has no known aetiology or pathophysiology. Recent investigations by other workers have suggested that individuals with CFS may have a hypercoagulable state. This...
  6. LarsSG

    The Occurrence of Hyperactivated Platelets and Fibrinaloid Microclots in ME/CFS, 2022, Nunes, Pretorius et al

    Abstract We have previously demonstrated that platelet poor plasma (PPP) obtained from patients with LongCovid/Post-Acute Sequelae of COVID-19 (PASC) is characterized by a hypercoagulable state reflected in hyperactivated platelets and the presence of considerable numbers of fibrin(ogen) amyloid...
  7. SNT Gatchaman

    Platelets amplify endotheliopathy in COVID-19, 2021, Barrett et al.

    Platelets amplify endotheliopathy in COVID-19 Tessa J. Barrett, MacIntosh Cornwell, Khrystyna Myndzar, Christina C. Rolling, Yuhe Xia, Kamelia Drenkova1, Antoine Biebuyck, Alexander T. Fields, Michael Tawil, Elliot Luttrell-Williams, Eugene Yuriditsky, Grace Smith, Paolo Cotzia, Matthew D. Neal...
  8. SNT Gatchaman

    Massive image-based single-cell profiling reveals high levels of circulating platelet aggregates in patients with COVID-19, 2021, Nishikawa et al

    Massive image-based single-cell profiling reveals high levels of circulating platelet aggregates in patients with COVID-19 Nishikawa, M., Kanno, H., Zhou, Y. et al. Abstract A characteristic clinical feature of COVID-19 is the frequent incidence of microvascular thrombosis. In fact, COVID-19...
  9. SNT Gatchaman

    Serum amyloid A binds to fibrin(ogen), promoting fibrin amyloid formation, 2019, Page et al

    Serum amyloid A binds to fibrin(ogen), promoting fibrin amyloid formation Martin J. Page, Greig J. A. thomson, J. Massimo Nunes, Anna-Mart Engelbrecht, Theo A Nell, Willem J. S. de Villiers, Maria C. de Beer, Lize Engelbrecht, Douglas B. Kell, Etheresia Pretorius Abstract Complex associations...
  10. SNT Gatchaman

    Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets, Bye et al, 2021

    Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets Alexander P. Bye, Willianne Hoepel, Joanne L. Mitchell, Sophie Jegouic, Silvia Loureiro, Tanya Sage, Gestur Vidarsson, Jan Nouta, Manfred Wuhrer, Steven de Taeye, Marit van Gils, Neline Kriek, Nichola...
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