pain

https://link.springer.com/article/10.1007/s10067-014-2517-2 Open access Abstract Low-dose naltrexone (LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn’s disease, multiple sclerosis, and complex regional pain syndrome. We review the evidence that...

Abstract Background The role of cytokines in the pathophysiology, diagnosis, and prognosis of small fiber neuropathy (SFN) is incompletely understood. We studied expression profiles of selected pro- and anti-inflammatory cytokines in RNA from white blood cells (WBC) of patients with a medical...

I really wonder how Drs in can give prescriptions for Oramoph and Tramadol but not medical marijuana.... Does anyone have any thoughts? https://www.independent.co.uk/life-style/health-and-families/multiple-sclerosis-symptoms-hereditary-cause-b2239253.html

Patel KV, Amtmann D, Jensen MP, Smith SM, Veasley C, Turk DC. Clinical outcome assessment in clinical trials of chronic pain treatments. Pain Rep. 2021 Jan 21;6(1):e784. doi: 10.1097/PR9.0000000000000784. PMID: 33521482; PMCID: PMC7837993. Abstract Clinical outcome assessments (COAs) measure...

Computational and neural mechanisms of statistical pain learning Flavia Mancini, Suyi Zhang, Ben Seymour Abstract Pain invariably changes over time. These fluctuations contain statistical regularities which, in theory, could be learned by the brain to generate expectations and control...

Cochrane PaPaS (Pain, Palliative and Supportive Care) : Trust, Integrity and the Future of Pain Evidence 7 Dec 2022 at 09:00 -- London & online Invitation "Pain in clinical practice and patient care is often poorly served by an evidence architecture containing multiple structural...

Men ages 39-65 needed for research study involving fibromyalgia and/or chronic fatigue syndrome The Neuroinflammation, Pain, and Fatigue Lab at UAB is currently recruiting men between the ages of 39-65 with Fibromyalgia and/or Chronic Fatigue Syndrome for a research study. This study combines...

Assessing sleep and pain among adults with myalgic encephalomyelitis/chronic fatigue syndrome: psychometric evaluation of the PROMIS® sleep and pain short forms Abstract Purpose To evaluate the psychometric properties of the patient-reported outcome measurement information system® (PROMIS)...

Trans-auricular vagus nerve stimulation to reduce perioperative pain and morbidity: protocol for a single-blind analyser-masked randomised controlled trial Amour B.U. Patel, Phillip P.W.M. Bibawy, Zehra Majeed, Weng Liang Gan, Gareth L. Ackland Background Established or acquired loss of...

'Looking Forward' to Another Year of ME.... This Chronic Elephant Blog is about how coping with the daunting prospect of another year of ME: https://thechronicelephant.blogspot.co.uk/2018/01/hippy-pants.html

https://www.firstwordhealthtech.com/story/5570485 Remedee Labs announced Thursday that the FDA granted a breakthrough therapy device designation to its endorphin stimulator for patients with fibromyalgia. CEO David Crouzier called the achievement a "major step, one that recognises [the...

https://www.science.org/doi/10.1126/scitranslmed.abj9954 Beneficial inflammation Chronic pain can develop from an acute pain state. The mechanisms mediating the transition from acute to chronic pain remain to be elucidated. Here, Parisien et al. focused on the immune system using samples from...

https://medicalxpress.com/news/2022-04-scientists-uncover-covid-pain.html

Moved post Apologies for this tangential post but I didn't want to start a new thread for this and it is relevant here. There is an article on pain management that is suggesting there will be non-opioid targeted pain relievers in the near future due to some research work in the US. Article...

An umbrella review of the literature on the effectiveness of psychological interventions for pain reduction https://bmcpsychology.biomedcentral.com/articles/10.1186/s40359-017-0200-5 Abstract Background Psychological interventions are widely implemented for pain management and treatment, but...

Abstract Patients recovering from COVID-19 may have persistent debilitating symptoms requiring long term support through individually tailored cardiopulmonary and psychological rehabilitation programs. Clinicians need to be aware about the likely long-term complications and their diagnostic...

Abstract Dysfunctional thalamocortical interactions have been suggested as putative mechanisms of ineffective pain modulation and also suggested as possible pathophysiology of fibromyalgia (FM). However, it remains unclear which specific thalamocortical networks are altered and whether it is...

Preventing progression from chronic to widespread pain and its impact on health-related quality of life: a historical cohort study of osteopathic medical care Abstract Context It is generally acknowledged that osteopathic physicians take a holistic approach to patient care. This style may help...

Abstract Objective To analyze opioid intake interference with psychological, well-being, and functional outcomes and medication tapering in patients with fibromyalgia admitted to the Mayo Clinic Pain Rehabilitation Program (MCPRP) in Florida. Patients and Methods A retrospective study on MCPRP...

Highlights • Stress may augment somatic symptoms in central sensitivity syndromes (CSS). • The COVID-19 pandemic offers a unique context to examine this hypothesis. • No convincing evidence indicated a COVID-19 stress-somatic symptoms link. • Also, no buffering effect of psychological...