pain

  1. Sly Saint

    Assessing sleep and pain among adults with ME/CFS: psychometric evaluation of the PROMIS®, 2022, Yang et al

    Assessing sleep and pain among adults with myalgic encephalomyelitis/chronic fatigue syndrome: psychometric evaluation of the PROMIS® sleep and pain short forms Abstract Purpose To evaluate the psychometric properties of the patient-reported outcome measurement information system® (PROMIS)...
  2. SNT Gatchaman

    [Protocol] Trans-auricular vagus nerve stimulation to reduce perioperative pain and morbidity

    Trans-auricular vagus nerve stimulation to reduce perioperative pain and morbidity: protocol for a single-blind analyser-masked randomised controlled trial Amour B.U. Patel, Phillip P.W.M. Bibawy, Zehra Majeed, Weng Liang Gan, Gareth L. Ackland Background Established or acquired loss of...
  3. hellytheelephant

    The Chronic Elephant blog by hellytheelephant

    'Looking Forward' to Another Year of ME.... This Chronic Elephant Blog is about how coping with the daunting prospect of another year of ME: https://thechronicelephant.blogspot.co.uk/2018/01/hippy-pants.html
  4. B

    Remedee's endorphin stimulator for fibromyalgia gains FDA breakthrough status

    https://www.firstwordhealthtech.com/story/5570485 Remedee Labs announced Thursday that the FDA granted a breakthrough therapy device designation to its endorphin stimulator for patients with fibromyalgia. CEO David Crouzier called the achievement a "major step, one that recognises [the...
  5. Trish

    Acute inflammatory response via neutrophil activation protects against the development of chronic pain, 2022, Parisien et al.

    https://www.science.org/doi/10.1126/scitranslmed.abj9954 Beneficial inflammation Chronic pain can develop from an acute pain state. The mechanisms mediating the transition from acute to chronic pain remain to be elucidated. Here, Parisien et al. focused on the immune system using samples from...
  6. Sly Saint

    Scientists uncover why long COVID can cause pain

    https://medicalxpress.com/news/2022-04-scientists-uncover-covid-pain.html
  7. Snowdrop

    Pain management - discussion thread

    Moved post Apologies for this tangential post but I didn't want to start a new thread for this and it is relevant here. There is an article on pain management that is suggesting there will be non-opioid targeted pain relievers in the near future due to some research work in the US. Article...
  8. Trish

    An umbrella review of the literature on the effectiveness of psychological interventions for pain reduction, 2017, Markozannes et al.

    An umbrella review of the literature on the effectiveness of psychological interventions for pain reduction https://bmcpsychology.biomedcentral.com/articles/10.1186/s40359-017-0200-5 Abstract Background Psychological interventions are widely implemented for pain management and treatment, but...
  9. O

    COVID-19 and Chronic Fatigue Syndrome: An Endocrine Perspective, 2021, Bansal et al

    Abstract Patients recovering from COVID-19 may have persistent debilitating symptoms requiring long term support through individually tailored cardiopulmonary and psychological rehabilitation programs. Clinicians need to be aware about the likely long-term complications and their diagnostic...
  10. O

    Structural and functional thalamocortical connectivity study in female fibromyalgia, 2021, Kim et al

    Abstract Dysfunctional thalamocortical interactions have been suggested as putative mechanisms of ineffective pain modulation and also suggested as possible pathophysiology of fibromyalgia (FM). However, it remains unclear which specific thalamocortical networks are altered and whether it is...
  11. O

    Preventing progression from chronic to widespread pain and its impact on health-related quality of life, 2021, Licciardone

    Preventing progression from chronic to widespread pain and its impact on health-related quality of life: a historical cohort study of osteopathic medical care Abstract Context It is generally acknowledged that osteopathic physicians take a holistic approach to patient care. This style may help...
  12. Andy

    Outcomes of a Comprehensive Pain Rehabilitation Program for Patients With Fibromyalgia, 2021, Engleberg-Cook et al

    Abstract Objective To analyze opioid intake interference with psychological, well-being, and functional outcomes and medication tapering in patients with fibromyalgia admitted to the Mayo Clinic Pain Rehabilitation Program (MCPRP) in Florida. Patients and Methods A retrospective study on MCPRP...
  13. Andy

    The impact of COVID-19 stress on pain and fatigue in people with and without a central sensitivity syndrome, 2021, Kopperta et al

    Highlights • Stress may augment somatic symptoms in central sensitivity syndromes (CSS). • The COVID-19 pandemic offers a unique context to examine this hypothesis. • No convincing evidence indicated a COVID-19 stress-somatic symptoms link. • Also, no buffering effect of psychological...
  14. Grigor

    Fibromyalgia and ME/CFS: an interoceptive predictive coding model of pain and fatigue expression, 2021, Sharp et al

    Harriet Sharp1,2, Kristy Themelis1,3, Marisa Amato1, Andrew Barritt1, Kevin Davies1, Neil Harrison1,4, Sarah Garfinkel1,5, Hugo Critchley1,2, Jessica Eccles1,2 Abstract: Introduction: The aetiology and pathophysiology of fibromyalgia and ME/CFS are poorly characterised but altered...
  15. Andy

    BBC Article Oct 2021: Gene silencing medicine transforms crippling pain

    Quote: An innovative type of medicine - called gene silencing - is set to be used on the NHS for people who live in crippling pain. The drug treats acute intermittent porphyria, which runs in families and can leave people unable to work or have a normal life. Clinical trials have shown severe...
  16. J

    Effect of Pain Reprocessing Therapy vs Placebo and Usual Care for Patients With Chronic Back Pain an RCT, 2021, Asher, Gordon et al

    https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2784694
  17. Hoopoe

    Trial methodology and patient characteristics did not influence the size of placebo effects on pain (2008) Kamper et al

    Objective To determine whether trial-design, patient-type, or placebo-type factors influence the size of the placebo analgesic effect in clinical trials. Study Design and Setting Trials that measured pain outcomes in Hróbjartsson and Gøtzsche's meta-analysis were retrieved and coded for eight...
  18. Wyva

    COVID-19 is getting on our nerves: sympathetic neural activity and hemodynamics in young adults recovering from SARS-CoV-2, 2021, Stute et al

    Abstract Key points The impact of SARS-CoV-2 infection on autonomic and cardiovascular function in otherwise healthy individuals is unknown. We show for the first time that young adults recovering from SARS-CoV-2 have elevated resting sympathetic activity, but similar heart rate and blood...
  19. Andy

    Conditioned pain modulation and pain sensitivity in functional somatic disorders: The DanFunD study, 2021, Petersen, Fink et al

    ABSTRACT Disrupted pain regulation has been proposed as a component in functional somatic disorders (FSD). The objective of this study was to examine a general population sample, encompassing three delimitations of FSD while assessing pain sensitivity and conditioning pain modulation (CPM)...
  20. Andy

    Brainstem damage is associated with poorer sleep quality and increased pain in gulf war illness veterans, 2021, Zhang et al

    Abstract Aims Gulf War Illness (GWI) is manifested as multiple chronic symptoms, including chronic pain, chronic fatigue, sleep problems, neuropsychiatric disorders, respiratory, gastrointestinal, and skin problems. No single target tissue or unifying pathogenic process has been identified that...
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