neuroinflammation

  1. Daisymay

    Gut Neuroinflammation Connection Revealed

    http://simmaronresearch.com/2019/01/gut-cure-neuroinflammation-m-s-mecfs-inquiry/ Gut Neuroinflammation Connection Revealed “There is something very critical about how the gut and brain are connected, and we’re starting to unravel the molecular threads behind that clinical observation. It’s a...
  2. Trish

    Collating Brain Research in ME

    The aim of this thread is to collect a list of brain imaging studies of ME patients, with links to threads on each study. We have in our library a thread by @Woolie that explains the different types of neuroimaging and what to look out for in assessing the quality of a study: Brain Studies of...
  3. Cheshire

    Evidence of widespread metabolite abnormalities in ME/CFS: assessment with whole-brain magnetic resonance spectroscopy (2019) Younger et al.

    Christina Mueller, Joanne C. Lin, Sulaiman Sheriff, Andrew A. Maudsley, Jarred W. Younger Behind a paywall https://link.springer.com/article/10.1007/s11682-018-0029-4
  4. Webdog

    Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10, 2019, Rojas et al

    Study: Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10 https://doi.org/10.1016/j.cell.2018.11.035 Press Release: Gut Immune Cells Cut Inflammation in Multiple Sclerosis https://www.ucsf.edu/news/2018/12/412941/gut-immune-cells-cut-inflammation-multiple-sclerosis
  5. adambeyoncelowe

    A compromised paraventricular nucleus within a dysfunctional hypothalamus: A novel neuroinflammatory paradigm for ME/CFS, 2018, Mackay, Tate.

    A compromised paraventricular nucleus within a dysfunctional hypothalamus: A novel neuroinflammatory paradigm for ME/CFS Angus MackayWarren P Tate First Published December 6, 2018 https://doi.org/10.1177/2058738418812342 Bolding in the quoted text mine for clarity.
  6. D

    Neuroinflammtion theory for Alzheimer's strikes a familiar note for pwME

    Neuroinflammation findings with Alzheimer's, strikes a familiar note for pwME regarding our own neurological symptoms. A CBC radio program aired on Quirks and Quarks on December 8, 2018, discusses the theory of amyloid-beta plaques in Alzheimer's, protecting the brain from infection...
  7. Kalliope

    frontiers in Neurology: Neuroinflammation and cytokines in ME/CFS: A critical review of research methods - Michael VanElzakker et al - 2018

    Review article is provisionally accepted and full text will be published soon Neuroinflammation and cytokines in ME/CFS: A critical review of research methods We argue that the vast majority of ME/CFS neuroimaging has failed to use optimal techniques for studying brainstem, despite its...
  8. MeSci

    Webinar - ME/CFS Involves Brain Inflammation: Results from a Ramsay Pilot Study - Jarred Younger

    Source: Solve ME/CFS Initiative Date: December 13, 2018 Time: 18:00-19:00 UTC URL: https://register.gotowebinar.com/register/1541028613190392835 ME/CFS Involves Brain Inflammation: Results from a Ramsay Pilot Study ---------------------------------------------------------- Presented by...
  9. J

    A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation

    https://www.nature.com/articles/s41467-018-04376-5 Wonder if PWCFS/ME have a Nlrp3 inflammasome signature and IL-1β expression in brain and cerebrospinal fluid, similar to MS Microglia, the mononuclear phagocytes of the central nervous system (CNS), are important for the maintenance of CNS...
  10. P

    Glial activation and expression of the serotonin transporter in chronic fatigue syndrome Noda et al(Japan) 2018

    Abstract: https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00589/abstract Provisionally accepted The full-text will be published soon.
  11. M

    Corticosterone and pyridostigmine/DEET exposure attenuate peripheral cytokine expression... neuroinflammation, mouse model, 2018, Michalovicz, Klimas

    Corticosterone and pyridostigmine/DEET exposure attenuate peripheral cytokine expression: supporting a dominant role for neuroinflammation in a mouse model of Gulf War Illness (2018) Michalovicz et al. (Drs Klimas, Fletcher are part of the authors) (I could not fit the whole title with the year...
  12. M

    Herpesvirus trigger accelerates neuroinflammation in a nonhuman primate model of multiple sclerosis

    Significance Inflammatory processes drive the autoimmune disease multiple sclerosis (MS). However, what triggers this inflammation re- mains unknown. Several herpesviruses (HHVs), such as HHV-6 typically acquired during childhood, are associated with MS. The temporal separation between...
  13. Sasha

    Jarred Younger confirms neuroinflammation in brains of ME patients

    Kidnapping Alex's post from another thread: Discuss! :)
  14. Jonathan Edwards

    Discussion - Does ME involve brain inflammation?

    Moderator note: The subject of brain inflammation in ME arose in this thread about a Netflix series. The discussion started with the following quote in post #32 from a doctor visiting a patient with ME shown in the film when explaining the word 'encephalomyelitis' in name ME may not be...
  15. Andy

    Nutritional modulation of the intestinal microbiota: future opportunities for the prevention and treatment of neuroimmune.., 2018, Palotas et al

    Put this in the biomed ME sub-forum as ME is one of the articles tags and one of the authors is De Meirleir. Paywalled at https://www.sciencedirect.com/science/article/pii/S0955286318301761?via%3Dihub
  16. Indigophoton

    Tracking peripheral immune cell infiltration of the brain in ME

    Very interesting sounding project from Jarred Younger, http://www.meresearch.org.uk/our-research/ongoing-studies/immune-cell-infiltration/
  17. Marco

    Long term depression associated with 'neuroinflammation'

    http://www.dailymail.co.uk/health/article-5438153/Years-depression-linked-brain-inflammation.html Not a new observation by any means but this is the first time I've seen measures of neuroinflammation quantified and correlated with duration.
  18. Andy

    Nature: "Neuroimmune communication"

    https://www.nature.com/articles/nn.4496
  19. Diwi9

    Neuroinflammation/PET research out of Japan

    Just wondering if anyone has seen these papers and has access to them. Stork delivered this to my inbox today and they look interesting. I keep waiting for a thread to pop up! ETA: I've deleted the links in this original post as moderation received notice that they are broken. Abstracts of...
  20. Sasha

    US: Jarred Younger wants ME/CFS & fibro patients who can get to Birmingham, Alabama for study

    Details here of this ongoing study: And in case people can't see that without a FB account:
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