neuroinflammation

This research article in the Journal of The Royal New Zealand College of General Practitioners has just been brought to my attention... http://www.publish.csiro.au/HC/fulltext/HC19041 A neuro-inflammatory model can explain the onset, symptoms and flare-ups of myalgic encephalomyelitis/chronic...

https://neurosciencenews.com/inflammation-drugs-dementia-15285/

If those numbers are reliable this is a borderline epidemic level crisis. Nearly 1/5 of the UK population reporting significant cognitive symptoms interfering with daily life but are typically brushed off by medicine. The worldwide numbers would place this at above 1B. That's staggering...

Bragée Clinic in Sweden is planning a study looking at 'Craniocervical dysfunction, neuroinflammation and infection in ME/CFS ws healthy controls' Jonas Bergquist from OMF's research center in Uppsala, among others. ETA: The study will include 80 patients from the Bragée clinic with an...

Review Neuroimmunology: What Role for Autoimmunity, Neuroinflammation, and Small Fiber Neuropathy in Fibromyalgia, Chronic Fatigue Syndrome, and Adverse Events after Human Papillomavirus Vaccination? https://www.mdpi.com/1422-0067/20/20/5164/htm

https://www.sciencedirect.com/science/article/abs/pii/S0026049519301489

Moderator note: This post has been copied from this thread: Brain inflammation

https://www.physiology.org/doi/abs/10.1152/ajpheart.00680.2018?journalCode=ajpheart This isn't ME/CFS research but it's not unrelated either, so I thought this should be in the ME/CFS research section.

Edited abstract : https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000307

Epstein-Barr Virus dUTPase Induces Neuroinflammatory Mediators: Implications for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. https://www.ncbi.nlm.nih.gov/pubmed/?term=Williams PhD MV[Author]&cauthor=true&cauthor_uid=31040055 Abstract PURPOSE: Neuroinflammation is a common feature in...

I took Valcyte for 2 1/2 years. I had suspected infectious onset based on initial fever and symptoms, as well as chronically very high EBV, CMV, HHV-6 antibody titers. Valcyte didn’t have any effect on my ME, though I was working full-time and push-crashing all the time. Valcyte also had this...

http://simmaronresearch.com/2019/01/gut-cure-neuroinflammation-m-s-mecfs-inquiry/ Gut Neuroinflammation Connection Revealed “There is something very critical about how the gut and brain are connected, and we’re starting to unravel the molecular threads behind that clinical observation. It’s a...

The aim of this thread is to collect a list of brain imaging studies of ME patients, with links to threads on each study. We have in our library a thread by @Woolie that explains the different types of neuroimaging and what to look out for in assessing the quality of a study: Brain Studies of...

Christina Mueller, Joanne C. Lin, Sulaiman Sheriff, Andrew A. Maudsley, Jarred W. Younger Behind a paywall https://link.springer.com/article/10.1007/s11682-018-0029-4

Study: Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10 https://doi.org/10.1016/j.cell.2018.11.035 Press Release: Gut Immune Cells Cut Inflammation in Multiple Sclerosis https://www.ucsf.edu/news/2018/12/412941/gut-immune-cells-cut-inflammation-multiple-sclerosis

A compromised paraventricular nucleus within a dysfunctional hypothalamus: A novel neuroinflammatory paradigm for ME/CFS Angus MackayWarren P Tate First Published December 6, 2018 https://doi.org/10.1177/2058738418812342 Bolding in the quoted text mine for clarity.

Neuroinflammation findings with Alzheimer's, strikes a familiar note for pwME regarding our own neurological symptoms. A CBC radio program aired on Quirks and Quarks on December 8, 2018, discusses the theory of amyloid-beta plaques in Alzheimer's, protecting the brain from infection...

Review article is provisionally accepted and full text will be published soon Neuroinflammation and cytokines in ME/CFS: A critical review of research methods We argue that the vast majority of ME/CFS neuroimaging has failed to use optimal techniques for studying brainstem, despite its...

Source: Solve ME/CFS Initiative Date: December 13, 2018 Time: 18:00-19:00 UTC URL: https://register.gotowebinar.com/register/1541028613190392835 ME/CFS Involves Brain Inflammation: Results from a Ramsay Pilot Study ---------------------------------------------------------- Presented by...

https://www.nature.com/articles/s41467-018-04376-5 Wonder if PWCFS/ME have a Nlrp3 inflammasome signature and IL-1β expression in brain and cerebrospinal fluid, similar to MS Microglia, the mononuclear phagocytes of the central nervous system (CNS), are important for the maintenance of CNS...