Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease with a complex clinical presentation and an unknown etiology. Various viral infections have been proposed as potential triggers of ME/CFS onset, but no specific pathogen has been identified in all cases of...
Stanford Medicine: Potential Role of Tetrahydrobiopterin Deficiency in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
You are invited to participate in a research study of chronic, unexplained fatigue, which is a kind of fatigue that does not improve with rest. Medically...
Dynamics of sleep stage transitions in healthy humans and patients with chronic fatigue syndrome
Akifumi Kishi, Zbigniew R. Struzik, Benjamin H. Natelson, Fumiharu Togo, Yoshiharu Yamamoto
Abstract
Physiological and/or pathological implications of the dynamics of sleep stage transitions have...
Sleep abnormalities in chronic fatigue syndrome/myalgic encephalomyelitis: a review
Melinda L Jackson, Dorothy Bruck
Abstract
Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a chronic, disabling illness that affects approximately 0.2% of the population. Non-restorative sleep...
Guardian angels off duty? ME/CFS is Sustained by an Impaired Stress Response in the Central Nervous System
Herbert Renz-Polster
Abstract
ME/CFS researchers agree that ME/CFS is a multisystem disease with a multitude of pathobiological features including endothelial dysfunction, immune...
https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2024.1460157/full
Cognitive assessment in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a cognitive substudy of the multi-site clinical assessment of ME/CFS (MCAM)
Introduction: Patients with Myalgic...
https://cep.health/clinical-products/fm-mecfs-pots/
Introduction
Fibromyalgia (FM), Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), and Postural Orthostatic Tachycardia Syndrome (POTS) are chronic health conditions. Accurate diagnosis and targeted management can improve the...
Effect of high dose vitamin C on Epstein-Barr viral infection
Nina A Mikirova, Ronald Hunninghake
Background
Many natural compounds were tested for the ability to suppress viral replication. The present manuscript details an analysis of high dose vitamin C therapy on patients with EBV...
Background
Chronic overlapping pain conditions (COPCs), pain-related conditions that frequently occur together, may occur in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and could impact illness severity. This study aimed to identify comorbid COPCs in patients with...
A narrative review on the similarities and dissimilarities between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and sickness behavior
Gerwyn Morris, George Anderson, Piotr Galecki, Michael Berk, Michael Maes
Abstract
It is of importance whether myalgic encephalomyelitis/chronic...
Autoantibodies, Polymorphisms in the Serotonin Pathway, and Human Leukocyte Antigen Class II Alleles in Chronic Fatigue Syndrome
Oscar-Danilo Ortega-Hernandez, Mariaclara Cuccia, Sara Bozzini, Nicola Bassi, Samuel Moscavitch, Lina-Marcela Diaz-Gallo, Miri Blank, Nancy Agmon-Levin, Yehuda...
Molecular study of receptor for advanced glycation endproduct gene promoter and identification of specific HLA haplotypes possibly involved in chronic fatigue syndrome
N Carlo-Stella, S Bozzini, A De Silvestri, I Sbarsi, C Pizzochero, L Lorusso, M Martinetti, M Cuccia
Abstract
The receptor...
Overlapping Conditions in Long COVID at a Multisite Academic Center
Background: Many patients experience persistent symptoms after COVID-19, a syndrome referred to as Long COVID (LC). The goal of this study was to identify novel new or worsening comorbidities self-reported in patients with LC...
RESTORE ME: A RCT of Oxaloacetate for Improving Fatigue in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Alan B. Cash, Suzanne D. Vernon, Candace Rond, Saeed Abbaszadeh, Jen Bell, Brayden Yellman, David Kaufman
*[Provisionally accepted, full text not yet available]*
Abstract
The...
The effect of a polynutrient supplement on fatigue and physical activity of patients with chronic fatigue syndrome: a double‐blind randomized controlled trial
FM Brouwers, S Van Der Werf, G Bleijenberg, L Van Der Zee, JWM Van Der Meer
Background: The efficacy of dietary supplements in chronic...
Supplementation with Guanidinoacetic Acid in Women with Chronic Fatigue Syndrome
Sergej M Ostojic, Marko Stojanovic, Patrik Drid, Jay R Hoffman, Damir Sekulic, Natasa Zenic
Abstract
A variety of dietary interventions has been used in the management of chronic fatigue syndrome (CFS), yet no...
Background
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is associated with long-term disability and poor quality of life (QoL). Cardinal ME/CFS symptoms (including post-exertional malaise, cognitive dysfunction and sleep disturbances) have been observed in Post COVID-19 Condition...
Objectives
Long COVID-19 (LC) patients experience a number of chronic idiopathic symptoms that are highly similar to those of post-viral Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). We have therefore performed a systematic review and meta-analysis to determine the proportion of...
Dissatisfaction with the Swedish National Board of Health and Welfare's new knowledge support for post-infectious diseases such as ME and postcovid is simmering. Both healthcare professionals working with these diagnoses, researchers, and the patients themselves are raising serious concerns...
Reduced Natural Killer (NK) cell cytotoxicity is the most consistent immune finding in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS). Meta-analysis of the published literature determined the effect size of the decrement in ME/CFS. Databases were screened for papers comparing NK...
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