Advocating the role of trained immunity in the pathogenesis of ME/CFS; a mini review
Bart Humer, Willem A. Dik, Marjan A. Versnel
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Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex chronic disease of which the underlying (molecular)...
mtDNA deletion m.8753_16566 with < 10 % heteroplasmy in muscle and isolated complex-V dysfunction misinterpreted as chronic fatigue syndrome over 21-years
Josef Finsterer, Ana C. Fiorini, Fulvio A. Scorza, Carla A. Scorza
[No abstract]
Link | PDF (Clinics) [Open Access]
Abstract:
We proposed that cerebrospinal fluid would provide objective evidence for disrupted brain metabolism in myalgic encephalomyelitis/chronic fatigue syndroome (ME/CFS). The concept of postexertional malaise (PEM) with disabling symptom exacerbation after limited exertion that does not...
Unravelling the Connection Between Energy Metabolism and Immune Senescence/Exhaustion in Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Jente Van Campenhout, Yanthe Buntinx, Huan-Yu Xiong, Arne Wyns, Andrea Polli, Jo Nijs, Joeri L. Aerts, Thessa Laeremans, Jolien Hendrix...
I thought it could be worth setting up a separate thread on this.
These guidelines are separate to the NICE guidelines.
Here's some background information from the ME Advocates Ireland website:
https://meadvocatesireland.blogspot.com/2022/09/news-from-hse-re-clinical-guideline-for.html
The...
Full title: A comparison of genome-wide association analyses of persistent symptoms after Lyme disease, fibromyalgia, and myalgic encephalomyelitis – chronic fatigue syndrome
Annemarie G. Hirsch, Anne E. Justice, Amy Poissant, Cara M. Nordberg, Navya S. Josyula, John Aucott, Alison W. Rebman &...
Abstract
Systemic infection and inflammation impair mental function through a combination of altered attention and cognition. Here, we comprehensively review the relevant literature and report personal clinical observations to discuss the relationship between infection, peripheral inflammation...
HERV Dysregulation in a Case of Myalgic Encephalomyelitis and Multiple Sclerosis Responsive to Rituximab
Eva Martín-Martínez, Sara Gil-Perotin, Karen Giménez-Orenga, Lucas Barea-Moya, Elisa Oltra
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Abstract
This article summarizes the case of 30-year-old male diagnosed with...
Dysregulation of lipid metabolism, energy production, and oxidative stress in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Gulf War Syndrome and Fibromyalgia
Leah Davis, Maisy Higgs, Ailsa Snaith, Tiffany A Lodge, James Strong, Jose Oltra, Sławomir Kujawski, Pawel Zalewski, Etheresia...
SciShow has over 8 million subscribers. They just released a video on ME/CFS.
It’s surprisingly accurate, and they even cover the PACE trial. The video is 8:11 long.
The Physical and Mental Health of Post-9/11 Female and Male Veterans: Findings from the Comparative Health Assessment
Erin K. Dursa, Yasmin S. Cypel, William J. Culpepper, Paul A. Bernhard, and Aaron I. Schneiderman
Background
Females are the fastest-growing group in the veteran population...
Possible Racial Disparities in the Diagnosis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Chloe Lisette Jones, Jarred Younger
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Abstract
Myalgic encephalomyelitis (ME/CFS) a chronic, disabling illness with no established etiopathology. It has been indicated...
Background
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex, debilitating condition characterised by severe fatigue that is not relieved by rest and is often exacerbated by physical or mental activity. A key challenge for individuals with ME/CFS is energy management and...
Abstract
Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM) often co-occur as medically unexplained conditions linked to disrupted physiological regulation, including altered sleep. Building on the work of Kishi et al. [7], who identified differences in sleep-stage transitions in CFS and...
Abstract:
Background
Documenting Long COVID cases has been challenging partly due to the lack of population-level data and uncertain diagnostic criteria, hindering the ability to ascertain healthcare utilization patterns over time. The objective of this study is to examine the characteristics...
Analysis of Cytokine Data in a Case-Control Study of ME/CFS
Navya Amaratunga
Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, chronic, and debilitating multi-system disease characterized by profound fatigue, post-exertional malaise (PEM), unrefreshing sleep...
https://www.lidsen.com/journals/neurobiology/neurobiology-09-01-267
Abstract
Following mental or physical exertion, patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) experience Post-Exertional Malaise (PEM). Although self-report questions represent less expensive and...
Abstract
Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease of unknown aetiology characterised by symptoms of post-exertional malaise (PEM) and fatigue leading to substantial impairment in functioning. Other key symptoms include cognitive impairment and...
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