Abstract:
Background
Sphingomyelin phosphodiesterase acid-like 3B (SMPDL3B) is emerging as a potential biomarker and therapeutic target in myalgic encephalomyelitis (ME), a complex multisystem disorder characterized by immune dysfunction, metabolic disturbances, and persistent fatigue. This...
Received via email about a new book download with a link to an online 3 day event on 17-19, July 2025. Sharing only so people know what so called experts are presenting as fact.
Email Contents
ME/CFS affects 2.5 million Americans, yet 90% remain undiagnosed. For decades, patients have searched...
Abstract
While post-infectious (PI-ME/CFS) and gradual onset (GO-ME/CFS) myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) manifest similar symptoms, it has long been suspected that different disease processes underlie them.
However, the lack of biological evidence has left this...
Reaction time deficits in a 3D virtual reality test in patients with ME/CFS
Anja-Maria Ladek; Marianna Lucio; Christian Y Mardin; Bettina Hohberger
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Purpose
Chronic Fatigue Syndrome (ME/CFS) is a debilitating post-infectious disorder affecting approximately 140,000–310,000...
Abstract:
Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Post-Acute Sequelae of COVID-19 (PASC) often have neurocognitive complaints that involve memory and concentration problems and difficulties paying attention. Other neurocognitive domains such as...
https://www.preprints.org/manuscript/202507.0058/v1
Abstract
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating, multi-system disease characterized by profound fatigue, post-exertional malaise (PEM), and a constellation of immune, neurological, and autonomic symptoms...
https://www.sciencedirect.com/science/article/abs/pii/S1542012425000850
The Ocular Surface
Volume 38, October 2025, Pages 64-71
Heightened visual light sensitivity discomfort measured by the ocular photosensitivity analyzer is associated with chronic ocular pain
Ema V. Karakoleva a b c...
Full title:
Immune Signatures in Post-Acute Sequelae of COVID-19 (PASC) and Myalgia/Chronic Fatigue Syndrome (ME/CFS): Insights from the Fecal Microbiome and Serum Cytokine Profiles
Abstract
While there are many postulates for the etiology of post-viral chronic fatigue and other...
Now published. See post #35.
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There Is No Established Connection Between Long-COVID and Chronic Fatigue Syndrome
https://www.preprints.org/manuscript/202506.2016/v1
Abstract
Fatigue is the most common symptom of Long-COVID (LC), characterized by...
2011 study
Authors
Garcia L, Kerr J, Fletcher MA, Sol C, Klimas N.
Institution
University of Miami Miller School of Medicine and Miami VA Medical Center, Miami, Florida, USA, and St George’s University of London, London, UK
]Funding
The study was funded by a research grant ME Research UK...
Abstract:
Background/Objectives: The aetiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), a chronic and severe debilitating disease with a complex phenotype, remains elusive. Associations with infectious diseases and autoimmune and neuropsychiatric disorders have been...
Investigating liminality in the lived experiences of young adults with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
Toller, L
University of Exeter
PhD in Sociology
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Abstract
This study investigates the lived experiences of young adults (aged 18-25) with...
The pivotal role of central sensitization in long COVID, fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome
Don L. Goldenberg
Introduction
Long COVID is a condition characterized by persistent unexplained symptoms following COVID-19 infection. These symptoms are not related to...
Abstract
The underlying pathologies driving post-acute infectious syndromes (e.g. myalgic encephalomyelitis / chronic fatigue syndrome, long COVID, etc) remain poorly understood. Given the extreme burden these illnesses impose on suffers, and the dramatic increase in cases following the COVID-19...
The Implications and Predictability of Sleep Reversal for People with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Machine Learning Approach
Meghan P. Dietrich, Raam Pravin, Jacob Furst, Leonard A. Jason
Background/Objectives:
Impaired sleep is one of the core symptoms of myalgic...
Low Dose Rapamycin Alleviates Clinical Symptoms of Fatigue and PEM in ME/CFS Patients via Improvement of Autophagy
Brian T. Ruan, Sarojini Bulbule, Amy Reyes, Bela Chheda, Lucinda Bateman, Jennifer Bell, Braydon Yellman, Stephanie Grach, Jon Berner, Daniel L. Peterson, David Kaufman, Avik Roy...
Full title:
Evaluating Pacing Therapy (PT) versus Graded Exercise Therapy (GET) for improving fatigue, pain, and quality of life in adults with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Systematic Review...
Full title:
The Effect on Quality of Life of Therapeutic Plasmapheresis and Intravenous Immunoglobulins on a Population of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients with Elevated β-Adrenergic and M3-Muscarinic Receptor Antibodies—A Pilot Study...
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