me/cfs

  1. forestglip

    Affective and chronic fatigue symptoms are associated with serum neuronal damage markers in Parkinson’s disease, 2025, Al-Hakeim et al

    Affective and chronic fatigue symptoms are associated with serum neuronal damage markers in Parkinson’s disease Hussein Kadhem Al-Hakeim, Hayder Naji Khudhair, Sayed-Omid Ranaei-Siadat, Fataneh Fatemi, Fateme Mirzajani , Mengqi Niu & Michael Maes [Line breaks added] Abstract Parkinson’s...
  2. Nightsong

    SMPDL3B a novel biomarker and therapeutic target in myalgic encephalomyelitis, 2025, Moreau, Fluge, Mella et al

    Abstract: Background Sphingomyelin phosphodiesterase acid-like 3B (SMPDL3B) is emerging as a potential biomarker and therapeutic target in myalgic encephalomyelitis (ME), a complex multisystem disorder characterized by immune dysfunction, metabolic disturbances, and persistent fatigue. This...
  3. W

    Webinar : Gordon Medical Forum Long COVID & ME/CFS, July17-19, 2025

    Received via email about a new book download with a link to an online 3 day event on 17-19, July 2025. Sharing only so people know what so called experts are presenting as fact. Email Contents ME/CFS affects 2.5 million Americans, yet 90% remain undiagnosed. For decades, patients have searched...
  4. John Mac

    Trial Report Distinct white matter alteration patterns in post-infectious and gradual onset chronic fatigue syndrome revealed by diffusion MRI, 2025, Yu et al

    Abstract While post-infectious (PI-ME/CFS) and gradual onset (GO-ME/CFS) myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) manifest similar symptoms, it has long been suspected that different disease processes underlie them. However, the lack of biological evidence has left this...
  5. forestglip

    Reaction time deficits in a 3D virtual reality test in patients with ME/CFS, 2025, Ladek et al

    Reaction time deficits in a 3D virtual reality test in patients with ME/CFS Anja-Maria Ladek; Marianna Lucio; Christian Y Mardin; Bettina Hohberger [Line breaks added] Purpose Chronic Fatigue Syndrome (ME/CFS) is a debilitating post-infectious disorder affecting approximately 140,000–310,000...
  6. Nightsong

    Two Neurocognitive Domains Identified for Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and [PASC], 2025, Jason et al

    Abstract: Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Post-Acute Sequelae of COVID-19 (PASC) often have neurocognitive complaints that involve memory and concentration problems and difficulties paying attention. Other neurocognitive domains such as...
  7. John Mac

    Review Redefining Mitochondrial Therapy for ME/CFS: The Case for MOTS-c, 2025, Klimas et al

    https://www.preprints.org/manuscript/202507.0058/v1 Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating, multi-system disease characterized by profound fatigue, post-exertional malaise (PEM), and a constellation of immune, neurological, and autonomic symptoms...
  8. Dolphin

    Heightened visual light sensitivity discomfort measured by the ocular photosensitivity analyzer is associated with chronic ocular pain, 2025, Karakole

    https://www.sciencedirect.com/science/article/abs/pii/S1542012425000850 The Ocular Surface Volume 38, October 2025, Pages 64-71 Heightened visual light sensitivity discomfort measured by the ocular photosensitivity analyzer is associated with chronic ocular pain Ema V. Karakoleva a b c...
  9. John Mac

    Immune Signatures in Post-Acute Sequelae of PASC and ME/CFS: Insights from the Fecal Microbiome and Serum Cytokine Profiles, 2025, Tobi et al

    Full title: Immune Signatures in Post-Acute Sequelae of COVID-19 (PASC) and Myalgia/Chronic Fatigue Syndrome (ME/CFS): Insights from the Fecal Microbiome and Serum Cytokine Profiles Abstract While there are many postulates for the etiology of post-viral chronic fatigue and other...
  10. John Mac

    Exploration of Intersections and Divergences of Long COVID and Chronic Fatigue Syndrome, 2025, Kouyoumdjian et al

    Now published. See post #35. --------------------------------------- There Is No Established Connection Between Long-COVID and Chronic Fatigue Syndrome https://www.preprints.org/manuscript/202506.2016/v1 Abstract Fatigue is the most common symptom of Long-COVID (LC), characterized by...
  11. forestglip

    Causal Relationship Between Diet, Lipids, Immune Cells, and Chronic Fatigue Syndrome: A Two-Mediation Mendelian Randomization Study, 2025, Li et al

    Causal Relationship Between Diet, Lipids, Immune Cells, and Chronic Fatigue Syndrome: A Two-Mediation Mendelian Randomization Study Jixu Li, Qi Qin, Yiran Zhu, Yulu Qian, Jialu Yin, Xin Gao, Huijuan Wen, Pei Wang [Line breaks added] Abstract Chronic fatigue syndrome (CFS) is a disorder...
  12. Hutan

    Comparing gene expression patterns in CFS and GWI using the Kerr ME/CFS Platform, 2011, Garcia, Kerr, Fletcher, Sol, Klimas

    2011 study Authors Garcia L, Kerr J, Fletcher MA, Sol C, Klimas N. Institution University of Miami Miller School of Medicine and Miami VA Medical Center, Miami, Florida, USA, and St George’s University of London, London, UK ]Funding The study was funded by a research grant ME Research UK...
  13. Nightsong

    Neurodevelopment Genes Encoding Olduvai Domains Link Myalgic Encephalomyelitis to Neuropsychiatric Disorders, 2025, Lidbury et al

    Abstract: Background/Objectives: The aetiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), a chronic and severe debilitating disease with a complex phenotype, remains elusive. Associations with infectious diseases and autoimmune and neuropsychiatric disorders have been...
  14. forestglip

    Thesis Investigating liminality in the lived experiences of young adults with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), 2025, Toller

    Investigating liminality in the lived experiences of young adults with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) Toller, L University of Exeter PhD in Sociology [Line breaks added] Abstract This study investigates the lived experiences of young adults (aged 18-25) with...
  15. forestglip

    The pivotal role of central sensitization in long COVID, fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome, 2025, Goldenberg

    The pivotal role of central sensitization in long COVID, fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome Don L. Goldenberg Introduction Long COVID is a condition characterized by persistent unexplained symptoms following COVID-19 infection. These symptoms are not related to...
  16. John Mac

    Preprint Hypothesis: A Mechanical Basis: Brainstem Dysfunction as a Potential Etiology of ME/CFS and Long COVID, 2025, Jeff Wood, Kaufman et al.

    Abstract The underlying pathologies driving post-acute infectious syndromes (e.g. myalgic encephalomyelitis / chronic fatigue syndrome, long COVID, etc) remain poorly understood. Given the extreme burden these illnesses impose on suffers, and the dramatic increase in cases following the COVID-19...
  17. forestglip

    The Implications and Predictability of Sleep Reversal for People with [ME/CFS]: A Machine Learning Approach, 2025, Dietrich, Jason et al

    The Implications and Predictability of Sleep Reversal for People with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Machine Learning Approach Meghan P. Dietrich, Raam Pravin, Jacob Furst, Leonard A. Jason Background/Objectives: Impaired sleep is one of the core symptoms of myalgic...
  18. forestglip

    Trial Report Low Dose Rapamycin Alleviates Clinical Symptoms of Fatigue and PEM in ME/CFS Patients via Improvement of Autophagy, 2025, Ruan et al

    Low Dose Rapamycin Alleviates Clinical Symptoms of Fatigue and PEM in ME/CFS Patients via Improvement of Autophagy Brian T. Ruan, Sarojini Bulbule, Amy Reyes, Bela Chheda, Lucinda Bateman, Jennifer Bell, Braydon Yellman, Stephanie Grach, Jon Berner, Daniel L. Peterson, David Kaufman, Avik Roy...
  19. John Mac

    Review Evaluating Pacing Therapy versus GET for improving fatigue, pain, and quality of life in adults with ME/CFS, 2025, Cooper

    Full title: Evaluating Pacing Therapy (PT) versus Graded Exercise Therapy (GET) for improving fatigue, pain, and quality of life in adults with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Systematic Review...
  20. John Mac

    Trial Report Effect on QoL of Therapeutic Plasmapheresis and Intravenous Immunoglobulins on a Population of ME/CFS Patients, 2025, Oesch-Regeni

    Full title: The Effect on Quality of Life of Therapeutic Plasmapheresis and Intravenous Immunoglobulins on a Population of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients with Elevated β-Adrenergic and M3-Muscarinic Receptor Antibodies—A Pilot Study...
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