Myalgic encephalomyelitis/chronic fatigue syndrome from current evidence to new diagnostic perspectives through skeletal muscle and metabolic disturbances
Tiziana Pietrangelo; Stefano Cagnin; Danilo Bondi; Carmen Santangelo; Lorenzo Marramiero; Cristina Purcaro; Raphael Severino Bonadio; Ester...
Full title: Comparison of the muscle oxygenation during submaximal and maximal exercise tests in patients post-coronavirus disease 2019 syndrome with pulmonary involvement
ABSTRACT
Introduction
Pulmonary involvement is prevalent in patients with coronavirus disease 2019 (COVID-19). Arterial...
Physical Activity, Long-COVID, and Inactivity: A Detrimental Endless Loop
Giuseppe Lippi; Camilla Mattiuzzi; Fabian Sanchis-Gomar
The risk of developing medium- and long-term sequelae after recovery from COVID-19 is validated. Long-COVID burden represents a major health care issue, thus paving...
Developing effective strategies to optimize physical activity and cardiorespiratory fitness in the long Covid population- The need for caution and objective assessment
Faghy; Duncan; Hume; Gough; Roscoe; Laddu; Arena; Asthon; Dalton
The Post Covid-19 Condition (commonly known as Long Covid) has...
Systems analysis of innate and adaptive immunity in Long COVID
Peluso; Abdel-Mohsen; Henrich; Roan
Since the onset of the COVID-19 pandemic, significant progress has been made in developing effective preventive and therapeutic strategies against severe acute SARS-CoV-2 infection. However, the...
Accelerated brain age in young to early middle-aged adults after mild to moderate COVID-19 infection
Shelli R Kesler; Oscar Y Franco-Rocha; Alexa De La Torre Schutz; Kimberly A. Lewis; Rija Aziz; Michael Brode; Esther Melamed
Cognitive decline is a common adverse effect of the Coronavirus...
Sex differences in post-acute neurological sequelae of SARS-CoV-2 and symptom resolution in adults after coronavirus disease 2019 hospitalization: an international multi-centre prospective observational study
605 authors not listed
Although it is known that coronavirus disease 2019 can present...
Merged threads
Low ferritin levels for pwME has been a mystery. My levels were normal when I was tested by an Internist during the first year of illness, but rapidly started decreasing for no apparent reason for many years after. I took iron supplements regularly. No one could figure...
Sex differences in symptomatology and immune profiles of Long COVID
Julio Silva; Takehiro Takahashi; Jamie Wood; Peiwen Lu; Sasha Tabachnikova; Jeffrey Gehlhausen; Kerrie Greene; Bornali Bhattacharjee; Valter Silva Monteiro; Carolina Lucas; Rahul Dhodapkar; Laura Tabacof; Mario Pena-Hernandez...
april
cmv
complement
cortisol
dendritic cells
ebv
endocrine
endocrine regulation
hsv2
immune system
interferon
longcovid
monocytes
nk cells
oestrogen
sex differences
t cells
testosterone
Long Covid and Impaired Cognition — More Evidence and More Work to Do
https://www.nejm.org/doi/full/10.1056/NEJMe2400189
The cardinal features of long Covid include fatigue, dysautonomia (or postural orthostatic tachycardia syndrome), postexertional malaise, and cognitive difficulties that are...
Employment outcomes of people with Long Covid symptoms: community-based cohort study
Ayoubkhani, Daniel; Zaccardi, Francesco; Pouwels, Koen B; Walker, A Sarah; Houston, Donald; Alwan, Nisreen A; Martin, Josh; Khunti, Kamlesh; Nafilyan, Vahé
BACKGROUND
Evidence on the long-term employment...
Severe COVID-19 and long COVID are associated with high expression of STING, cGAS and IFN-α
Queiroz, Maria Alice Freitas; Brito, Wandrey Roberto dos Santos; Pereira, Keise Adrielle Santos; Pereira, Leonn Mendes Soares; Amoras, Ednelza da Silva Graça; Lima, Sandra Souza; Santos, Erika Ferreira...
This thread includes some moved posts
Newsnight today 28th Feb- approx 10.45-55pm, introduced by Victoria Derbyshire
Study on cognitive impairment/ brain fog and IQ after long covid. A scientist from the study ( sorry I didn't catch the name of the author or his institution) and a ?scientist...
Preprint
Blood-brain barrier disruption in Long COVID-associated cognitive impairment
Chris Greene, Ruairi Connolly, Declan Brennan, Aoife Laffan, Eoin O'Keeffe, Lilia Zaporojan, Emma Connolly, Cliona Ni Cheallaigh, Niall Conlon, Colin Doherty, Matthew Campbell
Vascular disruption has been...
Abstract
Background
In the Netherlands, the prevalence of post COVID-19 condition is estimated at 12.7% at 90–150 days after SARS-CoV-2 infection. This study aimed to determine the occurrence of fatigue and other symptoms, to assess how many patients meet the Myalgic Encephalomyelitis/Chronic...
SARS-CoV-2 Spike Protein Downregulates Cell Surface α7nAChR through a Helical Motif in the Spike Neck
Tommy S. Tillman; Qiang Chen; Vasyl Bondarenko; Jonathan A. Coleman; Yan Xu; Pei Tang
A deficiency of the functional α7 nicotinic acetylcholine receptor (α7nAChR) impairs neuronal and immune...
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