long covid

Neuroinflammatory imaging markers in white matter: insights into the cerebral consequences of post-acute sequelae of COVID-19 PASC Sean Clouston; Chuan Huang; Jia Ying; Zennur Sekendiz; Minos Kritikos; Ashley Fontana; Lev Bangiyev; Benjamin Luft Symptoms of coronavirus disease 2019 (COVID-19)...

Why So Quiet about Long COVID? A top US epidemiologist pierces the silence about the pandemic’s deeply destructive long tail.

A genetically modulated Toll-like-receptor-tolerant phenotype in peripheral blood cells of children with multisystem inflammatory syndrome. Rehan Khan; Weizhen Ji; Jeisac Guzman-Rivera; Abhilasha Madhvi; Tracy Andrews; Benjamin Richlin; Christian Suarez; Sunanda Gaur; William Cuddy; Aalok R...

Plasma proteomic evidence for increased Alzheimer's disease-related brain pathology after SARS-CoV-2 infection Eugene P Duff; Henrik Zetterberg; Amanda Heslegrave; Abbas Dehghan; Paul Elliott; Naomi Allen; Heiko Runz; Rhiannon Laban; Elena Veleva; Christopher D Whelan; Benjamin B Sun; Paul M...

Attentional impairment and altered brain activity in healthcare workers after mild COVID-19 Lin, Keyi; Gao, Yaotian; Ji, Wei; Li, Yan; Wang, Wei; Du, Mengcheng; Liu, Jia; Hong, Zhengyu; Jiang, Tao; Wang, Yuyang Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) is highly transmissible...

International Care programs for Pediatric Post-COVID Condition Long COVID and the way forward Brackel, Caroline L. H.; Noij, Lieke C. E.; Vijverberg, Susanne J. H.; Legghe, Camille L.; Maitland-van der Zee, Anke H.; van Goudoever, Johannes B.; Buonsenso, Danilo; Munblit, Daniel; Sigfrid, Louise...

Abstract Long coronavirus disease (COVID) is the development or persistence of symptoms after an acute SARS-CoV-2 (COVID-19) infection. Fewer patients are developing acute COVID-19 infections, but patients with long COVID continue to have alarming long-term sequelae. Many cardiac magnetic...

COVID-19-related retinal microvasculopathy and systemic implications in patients with severe disease: results from the Methuselah study Castellino, Niccolò; Longo, Antonio; Russo, Andrea; Bonfiglio, Vincenza; Fallico, Matteo; Toro, Mario Damiano; Cappellani, Francesco; Grillo, Marco; Gaudio...

Repeated Hand Grip Strength is an Objective Marker for Disability and Severity of Key Symptoms in Post-COVID ME/CFS Anna Paffrath; Laura Kim; Claudia Kedor; Elisa Stein; Rebekka Rust; Helma Freitag; Uta Hoppmann; Leif G Hanitsch; Judith Bellmann-Strobl; Kirsten Wittke; Carmen Scheibenbogen...

Frequency, Characteristics, and Correlates of Cognitive Complaints in a Cohort of Individuals with Post-Acute Sequelae of COVID-19 Muschel, Cayla; Lynch, Sean T.; Dornbush, Rhea; Klepacz, Lidia; Shahar, Sivan; Ferrando, Stephen J. Background Cognitive complaints are among the most frequent...

Abstract BACKGROUND Following COVID-19, some patients present with ongoing symptoms like breathlessness and exercise limitations, even after mild acute infection. Research Question What is the exercise capacity of patients diagnosed with long COVID and does it change from baseline to the 1-year...

Abstract The diagnosis of long COVID is troublesome, even when functional limitations are present. Dynapenia is the loss of muscle strength and power production that is not caused by neurologic or muscular diseases, being mostly associated with changes in neurologic function and/or the intrinsic...

AC-73 and Syrosingopine Inhibit SARS-CoV-2 Entry into Megakaryocytes by Targeting CD147 and MCT4 Spinello, Isabella; Saulle, Ernestina; Quaranta, Maria Teresa; Pelosi, Elvira; Castelli, Germana; Cerio, Annamaria; Pasquini, Luca; Morsilli, Ornella; Dupuis, Maria Luisa; Labbaye, Catherine...

Effect of Paxlovid Treatment on Long COVID Onset: An EHR-Based Target Trial Emulation from N3C Alexander Preiss; Abhishek Bhatia; Chengxi Zang; Leyna V Aragon; John M Baratta; Monika Baskaran; Frank Blancero; M Daniel Brannock; Robert F Chew; Ivan Diaz; Megan Fitzgerald; Elizabeth P Kelly...

Brain Frontal-Lobe Misery Perfusion in COVID-19 ICU Survivors: An MRI Pilot Study Song, Jie; Khanduja, Shivalika; Rando, Hannah; Shi, Wen; Hazel, Kaisha; Pottanat, George Paul; Jones, Ebony; Xu, Cuimei; Hu, Zhiyi; Lin, Doris; Yasar, Sevil; Lu, Hanzhang; Cho, Sung-Min; Jiang, Dengrong Post-acute...

Children and young people with long COVID: overlooked and neglected Sanjana Jaidka; Eden Byrne We are two young people aged 19 and 20 years in the UK who both developed long COVID more than 2 years ago. This resulted in us being housebound for over a year, essentially taking a year out of our...

Cardiovascular effects of the post-COVID-19 condition Goerlich, Erin; Chung, Tae H.; Hong, Gloria H.; Metkus, Thomas S.; Gilotra, Nisha A.; Post, Wendy S.; Hays, Allison G. Throughout the COVID-19 pandemic, the new clinical entity of the postCOVID-19 condition, defined as a multisystemic...

Persistent complement dysregulation with signs of thromboinflammation in active Long Covid Open access: https://www.science.org/doi/10.1126/science.adg7942 Editor’s summary Some individuals can endure persistent, debilitating symptoms for many months after an initial severe acute respiratory...

Post-acute COVID-19 neuropsychiatric symptoms are not associated with ongoing nervous system injury 536 authors A proportion of patients infected with severe acute respiratory syndrome coronavirus 2 experience a range of neuropsychiatric symptoms months after infection, including cognitive...

There doesn't appear to be a thread for the federally-funded program contracted to Cochrane Canada and the McMaster University GRADE Centre to develop guidelines for Long Covid, which they call Post-COVID19 condition. The total funding appears to be $9M CAD. So far a few surveys have been sent...