gulf war illness

full paper here: https://bmjopen.bmj.com/content/9/8/e031114?rss=1

Full title Treatment for Gulf War Illness (GWI) with KPAX002 (methylphenidate hydrochloride + GWI nutrient formula) in subjects meeting the Kansas case definition: A prospective, open-label trial (revision 2) https://www.sciencedirect.com/science/article/abs/pii/S0022395619302651 (not...

Open access at https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219531

All Having skimmed over contents over the past week, I can't see substantive difference between gulf war syndrome sufferers and being a pwME. I asked this due to its public policy and liability implications. Can anyone explain how gulf war syndrome is distinct from ME/CFS? I accept that there...

Alterations in DNA Methylation Status Associated with Gulf War Illness https://www.liebertpub.com/doi/full/10.1089/dna.2018.4469 This is Dr Klimas’ group- paywalled. Abstract Gulf War Illness (GWI) affects about 25% of Persian Gulf veterans with a cluster of chronic symptoms, including...

https://www.sciencedaily.com/releases/2019/02/190221141506.htm

Sponsor: VA Office of Research and Development https://clinicaltrials.gov/ct2/show/NCT02782780

https://www.mirror.co.uk/news/uk-news/veterans-debilitating-gulf-war-syndrome-13911872

Gulf War Illness: Unifying Hypothesis for a Continuing Health Problem https://www.mdpi.com/1660-4601/16/1/111 Abstract: An estimated 25%–32% of veterans of the 1991 Gulf War continue to experience multiple unexplained health problems known as Gulf War Illness (GWI). GWI encompasses chronic...

Something in the serum again... Link: http://www.jneurology.com/articles/human-immunoglobulin-g-igg-neutralizes-adverse-effects-of-gulf-war-illness-gwi-serum-in-neural-cultures-paving-the-way-to-immunoth.html

Fatigue in Gulf War Illness is associated with tonically high activation in the executive control network Author links open overlay panelWylieG.R.abcGenovaH.bcDobryakovaE.bcDeLucaJ.bcdChiaravallotiN.bcFalvoM.aceCookD.fg https://www.sciencedirect.com/science/article/pii/S2213158218303899

full article here: https://www.cjr.org/analysis/lyme-disease-contested-illness-empathy.php

Open access at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220213/

Corticosterone and pyridostigmine/DEET exposure attenuate peripheral cytokine expression: supporting a dominant role for neuroinflammation in a mouse model of Gulf War Illness (2018) Michalovicz et al. (Drs Klimas, Fletcher are part of the authors) (I could not fit the whole title with the year...

This study has been ongoing a while - they want your 23andME etc. data - but it's a long-term one that needs tons of patients so it's worth mentioning again: http://www.nova.edu/nim/research/mecfs-genes.html Interesting short video explaining what's what...

This was in my news alert, some press coverage about Dr Klimas’ work with Gulf War Illness. https://www.winknews.com/2018/07/04/breakthrough-in-gulf-war-illnesses-from-exposure-to-chemical-toxins/

[I'm not impressed with the way the abstract for this study is written] https://www.tandfonline.com/doi/full/10.1080/21641846.2018.1477034 Original Articles Double-blinded placebo-controlled cross-over pilot trial of naltrexone to treat Gulf War Illness Kori L. Brewer...

Interesting. I see there's already some published info on this. Achieving Remission in Gulf War Illness: A Simulation-Based Approach to Treatment Design https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508058/ A randomized, double-blind, placebo-controlled, crossover trial of mifepristone in Gulf...

Exploring the Diagnostic Potential of Immune Biomarker Co-expression in Gulf War Illness Link to paper here * Patients with ME are control in this study Authors: Gordon Broderick, Mary Ann Fletcher, Michael Gallagher, Zachary Barnes, Suzanne D. Vernon, Nancy G. Klimas Abstract Complex...

Paywalled at https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch170262