gulf war illness

Highlights • Gulf War Veterans with GWI experience PEM. • GWI had significantly lower post-exercise ACTB, COMT, and TLR4 gene expression. • Gene expression did not mediate symptom post-exercise symptom exacerbation. • Post-exercise gene expression differs from responses reported in ME/CFS. •...

Objective The aim of the study is to investigate relationships between inflammatory analytes and symptoms of pain and fatigue in Gulf War illness (GWI). Methods In this preliminary study, 12 male veterans meeting GWI criteria provided daily blood samples and symptom ratings over 25 days...

Abstract Impaired bioenergetics have been reported in veterans with Gulf War illness (VGWIs), including prolonged post-exercise recovery of phosphocreatine (PCr-R) assessed with 31Phosphorus magnetic resonance spectroscopy. The citric acid cycle (CAC) is considered the most important metabolic...

https://bjgplife.com/delicate-diagnosis-avoiding-harms-in-difficult-disputed-and-desired-diagnoses/ BJGP LONG READ ‘Delicate diagnosis’: avoiding harms in difficult, disputed, and desired diagnoses 7 October 2022 Margaret McCartney is an Honorary Senior Lecturer at the School of Medicine...

Full title: At the Root of 3 “Long” Diseases: Persistent Antigens Inflicting Chronic Damage on the Brain and Other Organs in Gulf War Illness, Long-COVID-19, and Chronic Fatigue Syndrome ABSTRACT: Several foreign antigens such as those derived from viruses and bacteria have been linked to...

Abstract Service in the Persian Gulf in 1991 is associated with increased reporting of symptoms and distress in a proportion of those who served there. Yet despite clear evidence of an increase in symptom burden and a decrease in well being, exhaustive clinical and laboratory based scientific...

Abstract Gulf War Illness (GWI) affects 25–35% of the 1991 Gulf War Veteran (GWV) population. Patients with GWI experience pain, fatigue, cognitive impairments, gastrointestinal dysfunction, skin disorders, and respiratory issues. In longitudinal studies, many patients with GWI have shown little...

Yoga!—Jared Younger https://www.sciencedirect.com/science/article/abs/pii/S0022395620310839 Abstract Many Veterans of the 1990–1991 Gulf War report symptoms of Gulf War Illness, a condition involving numerous chronic symptoms including pain, fatigue, and mood/cognition symptoms. Little is known...

Full title: Evaluation of a Gene–Environment Interaction of PON1 and Low-Level Nerve Agent Exposure with Gulf War Illness: A Prevalence Case–Control Study Drawn from the U.S. Military Health Survey’s National Population Sample https://ehp.niehs.nih.gov/doi/10.1289/EHP9009 Abstract Background...

Review of the Midbrain Ascending Arousal Network Nuclei and Implications for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Gulf War Illness (GWI) and Postexertional Malaise (PEM) Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS and Gulf War Illness (GWI) share...

Abstract Objective Conditions defined by persistent “medically unexplained” physical symptoms and syndromes (MUS) are common and disabling. Veterans from the Gulf War (deployed 1990–1991) have notably high prevalence and disability from MUS conditions. Individuals with MUS report that providers...

Abstract Background Altered red blood cell (RBC) deformability has been reported in Veterans with Gulf War Illness (GWI) who endorse exercise-induced symptom exacerbation and fatigue. However, it is unknown whether altered RBC deformability is worsened secondary to exercise. Objective To...

Differential Effects of Exercise on fMRI of the Midbrain Ascending Arousal Network Nuclei in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) and Gulf War Illness (GWI) in a Model of Postexertional Malaise (PEM) preprint Abstract Background: Myalgic Encephalomyelitis / Chronic...

Abstract The Boston University-based Gulf War Illness Consortium (GWIC) is a multidisciplinary initiative developed to provide detailed understanding of brain and immune alterations that underlie Gulf War illness (GWI), the persistent multisymptom disorder associated with military service in...

Abstract Aims The Gulf War Illness programs (GWI) of the United States Department of Veteran Affairs and the Department of Defense Congressionally Directed Medical Research Program collaborated with experts to develop Common Data Elements (CDEs) to standardize and systematically collect...

Highlights • Many Gulf War veterans have developed chronic, difficult-to-treat illnesses. • Biopsychosocial models can improve chronic illness diagnosis and treatment. • Experiential avoidance (EA) is a psychosocial mental/medical illness risk factor. • EA was associated with PTSD, depression...

Full title: Symptom attribution to a medically unexplained syndrome is associated with greater perceived severity and bothersomeness of symptoms in US military veterans Abstract Objective Medically unexplained symptoms (MUS) are prevalent among veteran and non-veteran populations. Current...

Full title: “Because the country, it seems though, has turned their back on me”: Experiences of institutional betrayal among veterans living with Gulf War Illness Highlights • Institutional betrayal can occur when institutions fail to protect constituents from harm. • Veterans living with Gulf...

Full title: Moderate, Intermittent Voluntary Exercise in a Model of Gulf War Illness Improves Cognitive and Mood Function with Alleviation of Activated Microglia and Astrocytes, and Enhanced Neurogenesis in the Hippocampus Highlights • Moderate, intermittent voluntary exercise improved...

Abstract Aims There is controversy about brain volumes in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (CFS) and Gulf War Illness (GWI). Subcortical regions were assessed because of significant differences in blood oxygenation level dependent signals in the midbrain between these...