He had a slide showing that 11% develop ME/CFS from EBV, Ross River fever and Q fever; 50% develop it after SARS and MERS, but none developed after some other infections. He threw XMRV in there, which seemed a bit confusing, but helped to make his point of doing work in the field for a long time.
I did not listen to the presentations, so perhaps it's folded into those, but I could not find anything definitive in terms of cohorts' distribution through the US. My sense, based on the slides, is that a majority are from within the US, and of those, most come from the NorthEast/MidAtlantic Regions, and Western US. Also, I appreciate some are post-covid patients.
Lipkin's slide on infectious causes of ME/CFS intrigued me for a couple reasons.
First, he rules out some diseases as causes of ME/CFS, and I'd be curious to know by virtue of what tests he reached those conclusions. Did he test tissue, for instance?
Secondly, he highlights - literally - New York State, but on his list of infectious diseases to explore as contributory to ME/CFS, no where do we see any number of Borrelia species and strains, or babesia, or rickettsia, or bartonella....Which as a group, and in some areas it can be argued, individually, are ravaging the NorthEast US, and in particular, New York State. I know he's familiar with these, as his Tick Borne Disease Serochip (sp) kit suggests. For all you folks from the UK, this may seem like an unfair question, but I can assure you, in the US, and specifically in the MidAtlantic/NorthEast US, NOT looking at all the different tick-borne pathogens as possible causes for ME/CFS seems like a giant head-scratcher. Afterall, many are endemic here. Lyme, babesia and a certain type of rickettsia were first stumbled upon, according to some, off Long Island, NY back in the late '60's. Pretty much everybody in the NE US knows somebody who had at least one of those infections.
I know Lipkin was looking at this whole TBD thing, as was what's-his-name from southern California. But, sorry, if they ruled all of them out, I don't remember ever being informed
how those pathogens were ruled out, i.e, by what procedures.
I can assure you, in Lyme World, key Lyme investigators have been for close to 25 years claiming that patients thinking they had Lyme, didn't, but instead, after being infected with Lyme, were cured, and now had CFS. So, there is plenty of precedent for that sentiment. I'm left wondering why he didn't at least include one or two on his slide.