cerebrospinal fluid

  1. Snowdrop

    Variants in water channel gene tied to more restful sleep (The Scientist--article)

    Research on rodents. https://www.the-scientist.com/news-opinion/variants-in-water-channel-gene-tied-to-more-restful-sleep-67529 Paper here
  2. Hutan

    Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathione..., 2012, Shungu et al

    Abstract Chronic fatigue syndrome (CFS) is a complex illness, which is often misdiagnosed as a psychiatric illness. In two previous reports, using 1H MRSI, we found significantly higher levels of ventricular cerebrospinal fluid (CSF) lactate in patients with CFS relative to those with...
    • Hutan
    • Thread
    • cerebral hypoperfusion cerebrospinal fluid gsh lactate me/cfs mitochondrial dysfunction neuroimaging paper shungu
    • Replies: 2
    • Forum: ME/CFS research
  3. W

    Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease (Jan2020) Gate, M.Davis & Wyss-Coray, Stanford)

    This paper on Alzheimer’s is interesting because Mark Davis (one of the authors) and team are using similar techniques on ME patients to look for targets for T-Cell expansion. For Alzheimer's they found TCR's responding to two separate Epstein–Barr virus antigens in CSF...
  4. D

    Insights into the pathogenesis of ME/CFS through metabolomic profiling of cerebrospinal fluid, 2018, Fiehn - Preliminary results

    Link I thought I'd post this preliminary finding here so it gets some exposure. Credit to @wigglethemouse for digging in and finding this study. I believe it's part of Columbia's ME/CFS CFE and hopefully will be published soon.
    • dreampop
    • Thread
    • ccl11 cerebrospinal fluid columbia me/cfs metabolomics oliver fiehn pathogenesis
    • Replies: 3
    • Forum: ME/CFS research
  5. J

    Serological and metagenomic interrogation of cerebrospinal fluid implicates enteroviruses 2 in pediatric acute flaccid myelitis (2019) Schubert et al

    Preprint made available here. https://www.biorxiv.org/content/biorxiv/early/2019/06/10/666230.full.pdf
  6. Andy

    The putative glymphatic signature of chronic fatigue syndrome: A new view on the disease pathogenesis and therapy, 2018, Wostyn et al

    Paywalled at https://www.medical-hypotheses.com/article/S0306-9877(18)30548-6/fulltext
    • Andy
    • Thread
    • cerebrospinal fluid glymphatic system me/cfs pathogenesis
    • Replies: 31
    • Forum: ME/CFS research
  7. Andy

    Spinal fluid evacuation may provide temporary relief for patients with unexplained widespread pain and fibromyalgia, 2018, Hulens et al

    Paywalled at https://www.medical-hypotheses.com/article/S0306-9877(18)30428-6/fulltext
  8. M

    Systematic analysis of the cerebrospinal fluid proteome of fibromyalgia patients

    Abstract Fibromyalgia (FM) is a syndrome characterized by widespread muscular pain, fatigue and functional symptoms, which is known to be difficult to diagnose as the various symptoms overlap with many other conditions. Currently, there are no biomarkers for FM, and the diagnosis is made...
  9. Andy

    Elevations of ventricular lactate levels occur in both chronic fatigue syndrome and fibromyalgia, 2017, Natelson et al

    Paywalled at http://www.tandfonline.com/doi/abs/10.1080/21641846.2017.1280114?journalCode=rftg20 Study is from Feb 2017 but Solve have just posted a review of it: http://solvecfs.org/elevations-of-ventricular-lactate-levels-occur-in-both-chronic-fatigue-syndrome-and-fibromyalgia/
    • Andy
    • Thread
    • cerebrospinal fluid fibromyalgia lactate me/cfs natelson
    • Replies: 32
    • Forum: ME/CFS research
  10. Hoopoe

    Exercise-induced changes in cerebrospinal fluid miRNAs in Gulf War Illness, Chronic Fatigue Syndrome and sedentary control subjects, 2017, Baraniuk

    Exercise – induced changes in cerebrospinal fluid miRNAs in Gulf War Illness, Chronic Fatigue Syndrome and sedentary control subjects https://www.nature.com/articles/s41598-017-15383-9 By James Baraniuk and Narayan Shivapurkar.
    • Hoopoe
    • Thread
    • 2017 baraniuk cerebrospinal fluid exercise gulf war illness me/cfs paper
    • Replies: 63
    • Forum: ME/CFS research
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