Serological and metagenomic interrogation of cerebrospinal fluid implicates enteroviruses 2 in pediatric acute flaccid myelitis (2019) Schubert et al

I think this is now published as

Paywall, https://www.nature.com/articles/s41591-019-0613-1
Not currently available via Scihub

Article about this and another recent study, https://www.sciencemag.org/news/2019/10/evidence-links-poliolike-disease-children-common-type-virus

 

https://www.ucsf.edu/news/2019/10/4...HAsSPsa2ynYLfKVUTWfyXryLHq03HmMv-bPQ2ZVwkYsP4

 

Are there studies of searches for enteroviruses in the CSF of M.E. patients?

 

https://medicalxpress.com/news/2019...yzed-polio-like.amp?__twitter_impression=true

 

Do these findings make it more likely that an enterovirus may be involved in ME too?

 

I don't think so. If anything they emphasise how clinically different ME is from enteroviral infections.

 

Thanks, can you expand on that please?

 

Enteroviral infections like polio and this one produce permanent local nerve cell damage with corresponding clinical signs from a one off episode. ME does not produce local nerve cell damage as far as we know and the illness is chronic and fluctuating. There really is no similarity as far as I can see.

I think the whole discussion about ME and enteroviruses comes from the confusion raised by Acheson and others who muddled an acute epidemic that might or might not have been associated with focal neurological lesions and a chronic illness that followed in some case. Even if we think ME in recent times is in some cases precipitated by viral infections the acute illness and ME are completely different problems.