autoimmunity

BACKGROUND. Autoimmune diseases often have strong genetic associations with specific HLA-DR alleles. The synovial lesion in chronic inflammatory forms of arthritis shows marked upregulation of HLA-DR molecules, including in postinfectious Lyme arthritis (LA). However, the identity of...

Long-Term Adverse Effects of Mild COVID-19 Disease on Arterial Stiffness, and Systemic and Central Hemodynamics: A Pre-Post Study Podrug, Mario; Koren, Pjero; Dražić Maras, Edita; Podrug, Josip; Čulić, Viktor; Perissiou, Maria; Bruno, Rosa Maria; Mudnić, Ivana; Boban, Mladen; Jerončić, Ana...

https://www.frontiersin.org/articles/10.3389/fneur.2023.1137958/full Open access Team from Kagoshima, Japan Objective: Autoimmune autonomic ganglionopathy (AAG) is a rare disorder characterized by autonomic failure associated with the presence of anti-ganglionic acetylcholine receptor (gAChR)...

I found this from this tweet: CORA stands for "Congresses on Controversies in Rheumatology and Autoimmunity" and will hold their next conference in late March next year in Italy. I looked up their agenda and the first item to be discussed is this one: from this link...

Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity Briquez PS, Rouhani SJ, Yu J, Pyzer AR, Trujillo J, Dugan HL, Stamper CT, Changrob S, Sperling AI, Wilson PC, Gajewski TF, Hubbell JA, Swartz MA Patients infected...

Abstract Background Autoimmunity has been reported in patients with severe COVID-19. We investigated whether antinuclear/extractable-nuclear antibodies (ANAs) were present up to a year after infection, and if they were associated with the development of clinically relevant Post-Acute Sequalae...

Abstract Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating condition that can lead to severe impairment of physical, psychological, cognitive, social, and occupational functions. The cause of ME/CFS remains incompletely understood. There is no clinical...

https://www.nature.com/articles/d41586-021-01836-9

Funding announcement by the Swedish Cancer Society: Infections and autoimmunity: risk factors for chronic fatigue syndrome and subsequent B cell lymphoma and chronic lymphocytic leukemia development Anders Rosén Linköping University, Sweden 2022 SEK 1 600 000 Diagnosis: lymphoma Research...

Abstract Background: Myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) is a disabling multi-system complex disorder with prevalence of 875 per 100,000 (up to 3.4 million people) in the United States. There are no known etiologic or risk factors and no approved treatments for ME/CFS...

Abstract Autoimmunity has emerged as a characteristic of the post-COVID syndrome (PCS), which may be related to sex. In order to further investigate the relationship between SARS-CoV-2 and autoimmunity in PCS, a clinical and serological assessment on 100 patients was done. Serum antibody...

Abstract Background The immunopathological pathways enabling post-COVID syndrome (PCS) development are not entirely known. We underwent a longitudinal analysis of patients with COVID-19 who developed PCS aiming to evaluate the autoimmune and immunological status associated with this condition...

vvv Source: Medical Immunology Vol 23, #4, pp 975-980 Date: July/August 2021 URL: https://www.mimmun.ru/mimmun/article/view/2439 https://www.mimmun.ru/mimmun/article/view/2439/1456 Early diagnostics of autoinflammatory disorders associated with post-viral chronic fatigue...

https://pubmed.ncbi.nlm.nih.gov/34484936/ Abstract Objective: Postural tachycardia syndrome (POTS), the most common form of dysautonomia, may be associated with autoimmunity in some cases. Autoantibodies against the ganglionic acetylcholine receptor (gAChR) have been reported in a minority of...

Full title: Fine mapping of the major histocompatibility complex (MHC) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggests involvement of both HLA class I and class II loci Abstract The etiology of myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is unknown, but...

Population based study: atopy and autoimmune diseases are associated with functional dyspepsia and irritable bowel syndrome, independent of psychological distress Summary Background The pathogenesis of functional GI disorders (FGIDs) is uncertain. However, underlying immune activation and...

Pandemic insight The COVID-19 pandemic has pushed the link between viruses and autoimmunity into the spotlight. Over the past year, research suggesting that people with COVID-19 carry numerous autoantibodies in their blood has been widely reported — although the mechanism at play is as yet...

Panorama's Long Covid: Will I Ever Get Better? will be on BBC One at 19:35 BST on Monday 12 July and on BBC iPlayer (UK only) https://www.bbc.co.uk/news/health-57776010

Abstract. Estrogen-related receptor gamma (Esrrg) is a murine lupus susceptibility gene associated with T cell activation. Here, we report that Esrrg controls regulatory T cells (Treg) through mitochondria homeostasis. Esrrg deficiency impaired the maintenance and function of Treg cells...

PhD thesis https://www.duo.uio.no/bitstream/handle/10852/86195/1/PhD-Lande-2021.pdf https://www.duo.uio.no/bitstream/handle/10852/86195/PhD-Lande-2021.pdf Summary Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious and complex disease characterized by medically...