autoimmune

Platelet Storage Pool Deficiency and Elevated Inflammatory Biomarkers Are Prevalent in Postural Orthostatic Tachycardia Syndrome by William T. Gunning, Paula M. Kramer, Jacob A. Cichock, Beverly L. Karabin, Sadik A. Khuder, Blair P. Grubb doi.org/10.3390/cells11050774...

Abstract Chronic pain is the leading cause of life years lived with disability worldwide. The aetiology of most chronic pain conditions has remained poorly understood and there is a dearth of effective therapies. The WHO ICD-11 has categorised unexplained chronic pain states as ‘chronic primary...

Abstract Post COVID-19 Syndrome (PCS) is a complex of various symptoms developing a month or more after the acute phase of the disease. The cases of PCS development among patients with asymptomatic/mild forms are frequently reported; however, the pathogenesis of PCS in this group of patients is...

Antibodies against human endogenous retrovirus K102 envelope activate neutrophils in systemic lupus erythematosus Maria Tokuyama, Bronwyn M. Gunn, Arvind Venkataraman, Yong Kong, Insoo Kang, Tasfia Rakib, Michael J. Townsend, Karen H. Costenbader, Galit Alter and Akiko Iwasaki Journal of...

Full title: The Reification of the Clinical Diagnosis of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) as an Immune and Oxidative Stress Disorder: Construction of a Data-Driven Nomothethic Network and Exposure of ME/CFS Subgroups https://www.preprints.org/manuscript/202101.0623/v1

Lately I've been having attacks of red itchy inflammation. It doesn't look too bad on the pictures but it's sore and sometimes itches tremendously. I have very severe ME and although I've had very little light sensitivity, my sound sensitivity is worse and my touch sensitivity even worse. Having...

https://www.theguardian.com/science/2020/oct/25/the-dementia-that-can-be-cured The dementia that can be cured Treatments mentioned include steroids, rituximab and plasma exchange.

Increasing Prevalence of Antinuclear Antibodies in the United States. Dinse GE1, Parks CG2, Weinberg CR3, Co CA1, Wilkerson J1, Zeldin DC4, Chan EKL5, Miller FW6. Author information 1. Clinical and Public Health Sciences, Social & Scientific Systems, Durham, NC, U.S.A. 2. Epidemiology Branch...

Preliminary but interesting. Autism has been researched far more than ME and somehow this had been missed entirely. I would really like to see research done on post-mortem ME brains and spinal cords. This is the reason the researchers named this disease and there doesn't seem to have been any...

There are a number of references to chronic fatigue syndrome in this paper, including in the abstract, so I thought I would post it here, particularly given that Systrom is a co-author. He is now doing some ME/CFS research in the US. Free full text...

The main idea of the theory proposed is that in pre-modern times women were pregnant a lot of the time and the placenta was signaling the immune system to be chill. Now that women get pregnant much less, there is no longer that feedback from placentas that kept the immune system in check and...

https://www.ndcn.ox.ac.uk/study-with-us/continuing-professional-development/oxford-autoimmune-neurology-meeting-2019 The programme linked to on the event webpage seems to be outdated, Karl Morten has kindly sent me the version attached to this post. He will be speaking about the, currently...

https://neurosciencenews.com/narcolepsy-autoimmune-disease-10902/

Research that I'm sure most of us didn't know was needed ;) It mentions CFS but I refuse to take it seriously enough to put in any other sub-forum. Paywalled at https://www.sciencedirect.com/science/article/pii/S1550830718301265

Video talk https://powerhealthtalk.com/pots-more-evidence-that-it-is-autoimmune.htm

Have yet to watch it, but given Dr Systrom's SFNP findings, this may be interesting...

https://www.inquisitr.com/4964404/people-with-autoimmune-disorders-more-likely-to-have-psychosis-research-shows/

https://www.ncbi.nlm.nih.gov/pubmed/29635081 Autoimmun Rev. 2018 Apr 7. pii: S1568-9972(18)30088-0. doi: 10.1016/j.autrev.2018.01.009. [Epub ahead of print] Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - Evidence for an autoimmune disease. Sotzny F1, Blanco J2, Capelli E3, Castro-Marrero...

Paywalled at http://stke.sciencemag.org/content/11/526/eaap9415

The researchers looked at genetic and protein information from both healthy people and those with autoimmune conditions, using a newly developed technique. https://www.nih.gov/news-events/news-releases/epstein-barr-virus-protein-can-switch-risk-genes-autoimmune-diseases The paper...