aetiology

  1. O

    Do Anxiety and Depression Predict Persistent Physical Symptoms After a Severe COVID-19 Episode? A Prospective Study, 2021, Bottemanne et al

    Background: Persistent physical symptoms are common after a coronavirus disease 2019 (COVID-19) episode, but their pathophysiological mechanisms remain poorly understood. In this study, we aimed to explore the association between anxiety and depression at 1-month after acute infection and the...
  2. SNT Gatchaman

    An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome, Wirth et al, 2021

    An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome Klaus J. Wirth, Carmen Scheibenbogen and Friedemann Paul Abstract There is accumulating evidence of endothelial dysfunction, muscle and cerebral hypoperfusion in Myalgic...
    • SNT Gatchaman
    • Thread
    • 2021 aetiology cerebral blood flow dysautonomia endothelial function hypothesis intracranial hypertension me/cfs paper scheibenbogen wirth
    • Replies: 5
    • Forum: ME/CFS research
  3. Manuel

    Epstein-Barr Virus and the Origin of Myalgic Encephalomyelitis or Chronic Fatigue Syndrome, 2021, Manuel Ruiz-Pablos et al.

    After a long time and a lot of work, our hypothesis on the development of ME/CFS following an Epstein Barr virus infection has finally been published...
    • Manuel
    • Thread
    • 2021 aetiology ebv me/cfs paper pathogenesis ruiz-pablos
    • Replies: 5
    • Forum: ME/CFS research
  4. SNT Gatchaman

    The micro-clot finding in Long Covid — implications for the possible aetiology of ME/CFS

    Moved from Six-month sequelae of post-vaccination SARS-CoV-2 infection: a retrospective cohort study of 10,024 breakthrough infections, 2021, Taquet et al @Hutan thank you, I believe it's all coming together and Long Covid will have been instrumental. The Pretorius micro-clot finding is...
  5. Wyva

    Patient perceptions of infectious illnesses preceding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2021, Jason et al

    Abstract Objectives Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is often reported to be caused by an infectious agent. However, it is unclear whether one infectious agent might be the cause or whether there might be many different infectious agents. The objective of this study...
    • Wyva
    • Thread
    • 2021 aetiology depaul university infectious mononucleosis infectious trigger leonard jason me/cfs onset paper study
    • Replies: 6
    • Forum: ME/CFS research
  6. A

    The IDO2 tryptophan trap hypothesis

    There are some issues and concerns around the IDO2 tryptophan trap hypothesis about ME. These are my current thought directions, and should not be considered scientific fact. Please comment, add links, agree or disagree, or move this post to somewhere better if you are a moderator. Concerns...
    • alex3619
    • Thread
    • aetiology discussion thread hypothesis ido ido2 me/cfs tryptophan tryptophan trap
    • Replies: 7
    • Forum: ME/CFS research news
  7. Suffolkres

    Gulf War Illness - causes

    =AT25vxMZOC9yc2g7Plhs8S0Nodsy-Nbl5GfAPCIfkD5f_4dp1UvDI1FrEMp0re0Q6-UOr-hZgSynCHGySnIJ1ZILhDkUBnu8tTnApZnMYyfKVA4Kreex68tDR1ntF4S1F2VrfYqXVzNX6jW9SSQrVz_bkds']https://www.dailymail.co.uk/.../Gulf-War-syndrome-not... Gulf War syndrome which left 250,000 veterans suffering long-term fatigue and...
    • Suffolkres
    • Thread
    • acetylcholine aetiology antibiotics cholinesterase ciprofloxacin discussion thread fluoroquinolones gulf war illness gwi iraq iraq war
    • Replies: 68
    • Forum: Gulf War Illness
  8. John Mac

    Risks for Developing ME/CFS in College Students Following Infectious Mononucleosis: A Prospective Cohort Study, 2020, Jason et al

    Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) involves severe fatigue, unrefreshing sleep, and cognitive impairment, leading to functional difficulties; prior studies have not evaluated risk factors with behavioral and immune data collected prior to developing...
    • John Mac
    • Thread
    • aetiology cytokines ebv infectious mononucleosis leonard jason me/cfs no link with pre-existing mental illness pathogenesis psychological young people
    • Replies: 52
    • Forum: ME/CFS research
  9. Sly Saint

    Gulf War Illness Symptom Severity and Onset: A Cross-Sectional Survey : Baraniuk et al Feb 2020

    Cayla M Fappiano, USAF, James N Baraniuk, MD https://academic.oup.com/milmed/advance-article/doi/10.1093/milmed/usz471/5721123?searchresult=1
  10. Andy

    Pathological Mechanisms Underlying Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2019, Fisher et al.

    Now published, see https://www.s4me.info/threads/preprint-pathological-mechanisms-underlying-myalgic-encephalomyelitis-chronic-fatigue-syndrome-2019-fisher-et-al-now-published.10412/#post-190278 Preprint. Open access at https://www.preprints.org/manuscript/201907.0196/v1
    • Andy
    • Thread
    • 2019 aetiology fisher me/cfs missailidis paper
    • Replies: 7
    • Forum: ME/CFS research
  11. Sly Saint

    Myalgic encephalomyelitis or chronic fatigue syndrome: how could the illness develop?(2019) - G.Morris,Maes,Berk,Puri

    https://link.springer.com/article/10.1007%2Fs11011-019-0388-6
    • Sly Saint
    • Thread
    • 2019 aetiology basant puri berk maes me/cfs morris paper
    • Replies: 22
    • Forum: ME/CFS research
  12. ME/CFS Skeptic

    Post-bacterial infection chronic fatigue syndrome is not a latent infection. Melenotte et al. (2019).

    Epub ahead of print. French study, university of Marseille.
  13. Andy

    Onset patterns and course of myalgic encephalomyelitis/ chronic fatigue syndrome, 2019, Chu et al

    Open access at https://www.frontiersin.org/articles/10.3389/fped.2019.00012/abstract ETA: Change "Paywall" to "Open access"
    • Andy
    • Thread
    • 2019 aetiology chu epidemiology me/cfs montoya paper prognosis usa
    • Replies: 52
    • Forum: ME/CFS research
  14. Sasha

    The two age peaks in onset of ME/CFS

    @Jonathan Edwards, I remember that in the other place several of us had a long discussion about what could explain the two peaks in onset-age for ME/CFS. I just saw the graph that we were discussing reproduced in Slide #25 of Karl Morten's recent talk in NZ...
  15. Andy

    Investigating the aetiology of adverse events following HPV vaccination with systems vaccinology, 2018, Campbell-Tofte et al

    Paywalled at https://link.springer.com/article/10.1007%2Fs00018-018-2925-6
    • Andy
    • Thread
    • 2018 aetiology campbell-tofte hpv immunology me/cfs paper vaccination
    • Replies: 1
    • Forum: ME/CFS research
  16. Andy

    How chronic administration of benzodiazepines leads to unexplained chronic illnesses: A hypothesis, 2018, LaCorte

    Paywalled at https://www.medical-hypotheses.com/article/S0306-9877(18)30364-5/fulltext
    • Andy
    • Thread
    • 2018 aetiology calcium channels fibromyalgia hypothesis lacorte me/cfs nitric oxide paper
    • Replies: 6
    • Forum: ME/CFS research
  17. H

    The "Biology-First" Hypothesis: Functional disorders may begin and end with biology-A scoping review (2018)

    https://www.ncbi.nlm.nih.gov/pubmed/29956418 http://sci-hub.tw/https://onlinelibrary.wiley.com/doi/abs/10.1111/nmo.13394
    • hixxy
    • Thread
    • 2018 aetiology enck epidemiology me/cfs mus paper review
    • Replies: 2
    • Forum: ME/CFS research
  18. Andy

    Transient Receptor Potential Ion Channels in the Etiology and Pathomechanism of CFS/ME, 2018, Marshall-Gradisnik et al

    Open access at http://www.scirp.org/journal/PaperInformation.aspx?PaperID=84678
    • Andy
    • Thread
    • 2018 aetiology australia marshall-gradisnik me/cfs ncned paper
    • Replies: 2
    • Forum: ME/CFS research
  19. Andy

    Review: Antibodies against GPCR, 2018, Meyer and Heidecke

    Open access at http://www.bioscience.org/2018/v23/af/4698/fulltext.php
    • Andy
    • Thread
    • 2018 aetiology antibodies me/cfs meyer paper review
    • Replies: 0
    • Forum: ME/CFS research
  20. W

    Bustle magazine mentions CFS

    In an article discussing whether to excercise while ill (generally not; it won’t help, will infect others, and sometimes make you worse, the article advises, but says Mayo Clinic says it’s ok to expose your gym to a head cold—let’s hope there’s no one there with leukemia or on anti rejection...
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