USA: The RECOVER Initiative - Long Covid research

1/23/25: 'East Alabama Health partners with Duke, NIH to study Long COVID Treatments'

As part of the NIH’s RECOVER initiative, Drs. Nathan Douthit and Haley Clay are conducting clinical trials to test the safety and effectiveness of two potential treatments for patients with Long COVID.

“We are involved in the RECOVER-Autonomic arm, which means we are looking at the autonomic symptoms of Long COVID such as fast heart rate, dizziness, and fatigue,” said Dr. Douthit, principal investigator and director of EAMC’s Internal Medicine Residency Program. “I am excited to see what therapies develop as a result of this study and expand our knowledge of treatment for this condition.”
 
“I am excited to see what therapies develop as a result of this study and expand our knowledge of treatment for this condition.”

There are some words in this game that I regard as warning signs. A researcher/clinician being 'excited' about their latest idea is definitely one of them.
 
shak8 said:
I wish Tonix would give up on that. They've been at the sublingual flexeril for FM treatment for YEARS showing nil to poor efficacy.
Click to expand...

Ar en't the results of the RESILIENT study quite significant though, or do you consider that poor efficiency [no offense, genuine question]?
https://www.healthrising.org/blog/2024/04/15/tonix-tomnya-fibromyalgia-sleep-pain/

Meanwhile, they are going ahead with FDA approval:
https://ir.tonixpharma.com/news-eve...ceuticals-announces-that-fda-will-not-require
 
Last edited by a moderator:
Kronos said:
Ar en't the results of the RESILIENT study quite significant though, or do you consider that poor efficiency [no offense, genuine question]?
https://www.healthrising.org/blog/2024/04/15/tonix-tomnya-fibromyalgia-sleep-pain/

Meanwhile, they are going ahead with FDA approval:
https://ir.tonixpharma.com/news-eve...ceuticals-announces-that-fda-will-not-require
Click to expand...

Thanks for bringing this up @Kronos. I didn't realize there had more trials with stronger doses.

Here's Tonix's report of the trial. From FM researchers that I've read, they consider a 50-60% mean pain reduction significant.

Until I see a published report in a medical journal, I won't know how meaningful the pain reduction might be.

https://ir.tonixpharma.com/news-eve...harmaceuticals-announces-highly-statistically



(edited)
 
Last edited:
https://recovercovid.org/r3-seminar-series

April 08, 2025
12:00PM Eastern Time

Effectiveness of Paxlovid in Protecting Against Long COVID: EHR Insights
Speakers will present findings from two studies examining whether Paxlovid treatment in the acute phase of COVID-19 helps to prevent Long COVID. The study teams used electronic health records from the National Covid Cohort Collaborative (N3C) and the National Patient-Centered Clinical Research Networks (PCORnet) RECOVER repository.

Register for the seminar
 
leokitten said:
Devastating if this is true. They are terminating the entire RECOVER initiative right in the middle of it

https://cen.acs.org/policy/research-funding/NIH-cancels-RECOVER-grants-long/103/web/2025/03
Click to expand...
It doesn't look like they're explicitly shutting the whole RECOVER program down, based on the article. At least not yet.
According to Megan Fitzgerald, a researcher and advocate who works closely with RECOVER-funded researchers and who has long COVID herself, all grants for pathobiology studies that RECOVER funded in 2022 and 2023 were canceled this week. That amounts to 45 different studies that were designed to uncover the biological mechanisms that may drive various manifestations of long COVID.
Click to expand...
One study was aimed at uncovering whether people with long COVID have any underlying genetic particularities that make them susceptible to the condition, which is a chronic, systemic illness that can involve persistent inflammation, circulatory issues, and extreme, debilitating fatigue that leaves people bedbound in the most severe cases. Warburton’s other study, which involved teens and young adults, was designed to look at the physiology of brain fog—a common phrase for cognitive difficulties that include memory and recall issues and tiredness—as well as learn what might cause the participants’ inability to regulate their blood circulation.
Click to expand...
“The COVID-19 pandemic is over, and HHS will no longer waste billions of taxpayer dollars responding to a non-existent pandemic that Americans moved on from years ago,” HHS spokesperson Emily Hilliard says in an email to C&EN, invoking the Make America Healthy Again, or MAHA, movement spearheaded by HHS secretary Robert F. Kennedy Jr. “HHS is prioritizing funding projects that will deliver on President Trump’s mandate to address our chronic disease epidemic and Make America Healthy Again.”
Click to expand...
Fitzgerald spent part of her day Wednesday on a call with pediatric researchers whose RECOVER grants were terminated. She says they are very worried about the future of the program.

“For a lot of the researchers on the call, they kind of felt like this was a death knell for RECOVER entirely,” Fitzgerald says.
Click to expand...
 
all grants for pathobiology studies that RECOVER funded in 2022 and 2023 were canceled this week.​

Patients, in the USA at least, are being handed straight back to the psycho-behavioural gang to do as they wish. Except it will be worse this time.

We finally start getting somewhere, and then they rip the whole project away from under us.

I wonder how much this decision was influenced behind the scenes by those psychs?
 
leokitten said:
Given everything the admin has said about reorg and priorities and their actions so far, people should expect more than not that RECOVER will end
Click to expand...
Yeah, unfortunately. The choice of Bhattacharya made this inevitable. He was one of the sell-out main signatories of the "Great Barrington" plan. He obviously wants to cover up all the consequences.

It's weird, I don't even feel anything about it, I expected it to happen. I got to the point where I expected nothing out of it anyway, even if this wasn't happening, once the first bumbling around made it clear there is no one in charge there.

The worst case, most appallingly wrong, scenario. Every. Single. Time. This is the only reason why I keep saying that only AI can solve this. It's not because it's the only way, it's that humans are awful at this stuff and can't put in the effort they need to. Not after everything that happened. It's either a revolutionary transformation of everything, or nothing. I expect even worse news soon. Life just sucks.
 
“The COVID-19 pandemic is over, and HHS will no longer waste billions of taxpayer dollars responding to a non-existent pandemic that Americans moved on from years ago,” HHS spokesperson Emily Hilliard says in an email to C&EN, invoking the Make America Healthy Again, or MAHA, movement spearheaded by HHS secretary Robert F. Kennedy Jr. “HHS is prioritizing funding projects that will deliver on President Trump’s mandate to address our chronic disease epidemic and Make America Healthy Again.”
Click to expand...
What's darkly funny about this is that it's not even different than the last few decades. They say stuff. They don't mean the stuff they say. No one cares. Nothing happens. Failure from ideologues, or failure from other ideologues. It's all the same in the end.
 
Sean said:
I wonder how much this decision was influenced behind the scenes by those psychs?
Click to expand...
I doubt they had much say, but they are likely very happy with this, even if they wouldn't admit it publicly. For sure people like Walitt are very happy.

They are no different than literal chaos agents working for oligarchs uninterested in any concept of public health, who literally want to destroy the institutions tasked with it, and are motivated by covering up a giant crime, but the medical profession has already accepted their ideology so it goes largely unnoticed.

All of this should make them question everything they stand for. But they won't. Internet trolls and conspiracy fantasy communities have long loved their psychosomatic trash, and they don't even notice it. It's really absurd seeing how clownish and immature humanity is, top to bottom.
 
Has this been shared yet?

The Sick Times: 'UPDATE: RECOVER Long COVID pathobiology grants restored'

'Long COVID research grants from the National Institutes of Health’s RECOVER program will be restored following news stories about their abrupt cancellations and advocacy to restore the funding, according to patient representatives in the initiative.'

'This returned funding is a rare win for Long COVID advocates and researchers amid a climate of fear and uncertainty.'

From Nature reporter Max Kozlov:

https://bsky.app/profile/maxkozlov.bsky.social/post/3llhld2yzm22n

Text: "Confirming this scoop by@thesicktimes.bsky.social - an HHS source says that Sen. Todd Young (R-IN), who secured a commitment from RFK Jr. during his confirmation hearing that he'd continue funding long COVID research, intervened."
 
You must log in or register to reply here.
Back
Top Bottom